Neurologian yksikkö
Department of Neurology

Julkaisut 2016
Publications 2016

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1 Adams HH, Hibar DP, Chouraki V, ..., Soininen H, ..., Thompson PM. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci 2016:19(12):1569-1582.
2 Beishuizen CR, Stephan BC, van Gool Wa, Brayne C, Peters RJ, Andrieu S, Kivipelto M, Soininen H, Busschers WB, Moll van Charante EP, Richard E. Web-Based Interventions Targeting Cardiovascular Risk Factors in Middle-Aged and Older People: A Systematic Review and Meta- Analysis. J Med Internet Res 2016:18(3):e55.
3 Bruun E, Kälviäinen R, Keränen T. Outcome of initial antiepileptic drug treatment in elderly patients with newly diagnosed epilepsy. Epilepsy Res 2016:127:60-65.
4 Crespel A, Ferlazzo E, Franceschetti S, Genton P, Gouider R, Kälviäinen R, Korja M, Lehtinen MK, Mervaala E, Simonato M, Vaarmann A. Unverricht-Lundborg disease. Epileptic Dis 2016:18(S2):S28-S37.
5 Falahati F, Ferreira D, Soininen H, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Lovestone S, Eriksdotter M, Wahlund LO, Simmons A, Westman E. The Effect of Age Correction on Multivariate Classification in Alzheimer's Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects. Brain Topogr 2016:29(2):296-307.
6 Ferreira D, Cavallin L, Granberg T, ..., Soininen H, ..., for the AddNeuroMed consortium, and for the Alzheimer’s Disease Neuroimaging Initiative. Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition. Eur Radiol 2016:26(8):2597-610.
7 Franke B, Stein JL, Ripke S, ..., Soininen H, ..., Franke B, Thompson PM, Medland SE. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat Neurosci 2016:19(3):420-31.
8 Haapalinna F, Paajanen T, Penttinen J, Kokki H, Kokki M, Koivisto AM, Hartikainen P, Solje E, Hänninen T, Remes AM, Herukka SK. Low Cerebrospinal Fluid Amyloid-Beta Concentration Is Associated with Poorer Delayed Memory Recall in Women. Dement Geriatr Cogn Disord Extra 2016:6(2):303-312.
9 Halbgebauer S, Nagl M, Klafki H, Haußmann U, Steinacker P, Oeckl P, Kassubek J, Pinkhardt E, Ludolph AC, Soininen H, Herukka S, Wiltfang J, Otto M. Modified serpinA1 as risk marker for Parkinson's disease dementia: Analysis of baseline data. Sci Rep 2016:6:26145.
10 Huovinen J, Kastinen S, Komulainen S, Oinas M, Avellan C, Frantzen J, Rinne J, Ronkainen A, Kauppinen M, Lönnrot K, Perola M, Pyykkö OT, Koivisto AM, Remes AM, Soininen H, Hiltunen M, Helisalmi S, Kurki M, Jääskeläinen JE, Leinonen V. Familial idiopathic normal pressure hydrocephalus. J Neurol Sci 2016:368:11-18.
11 Huttunen J, Lindgren A, Kurki MI, Huttunen T, Frösen J, von und zu Fraunberg M, Koivisto T, Kälviäinen R, Räikkönen K, Viinamäki H, Jääskeläinen JE, Immonen A. Antidepressant Use After Aneurysmal Subarachnoid Hemorrhage: A Population-Based Case-Control Study. Stroke 2016:47(9):2242-8.
12 Julkunen P, Määttä S, Säisänen L, Kallioniemi E, Könönen M, Jäkälä P, Vanninen R, Vaalto S. Functional and structural cortical characteristics after restricted focal motor cortical infarction evaluated at chronic stage - Indications from a preliminary study. Clin Neurophysiol 2016:127(8):2775-84.
13 Junttila A, Kuvaja M, Hartikainen P, Siloaho M, Helisalmi S, Moilanen V, Kiviharju A, Jansson L, Tienari PJ, Remes AM, Herukka S. Cerebrospinal Fluid TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Patients with and without the C9ORF72 Hexanucleotide Expansion. Dement Geriatr Cogn Disord Extra 2016:6(1):142-9.
14 Kinnunen UM, Kivekäs E, Paananen P, Kälviäinen R, Saranto K. Testing of triggers by data mining of epilepsy patients' structured nursing records. In: Sermeus W, Procter PM, Weber P, eds. Nursing Informatics 2016 ; eHealth for All: Every Level Collaboration - From Project to Realization, p. 461-465. IMIA and IOS Press, 2016. Studies in Health Technology and Informatics. Vol. 225.
15 Kivekäs E, Kinnunen UM, Paananen P, Kälviäinen R, Haatainen K, Saranto K. Functionality of Triggers for Epilepsy Patients Assessed by Text and Data Mining of Medical and Nursing Records. In: Semeus W, Procter PM, Weber P, eds. Nursing Informatics 2016 ; eHealth for All : Every Level Collaboration - From Project to Realization, p. 128-132. IMIA and IOS Press, 2016. Studies in Health Technology and Informatics. Vol. 225.
16 Kobulashvili T, Höfler J, Dobesberger J, ..., Kälviäinen R, ..., Trinka E. Current practices in long-term video-EEG monitoring services: A survey among partners of the E-PILEPSY pilot network of reference for refractory epilepsy and epilepsy surgery. Seizure 2016:38:38-45.
17 Koikkalainen J, Rhodius-Meester H, Tolonen A, Barkhof F, Tijms B, Lemstra AW, Tong T, Guerrero R, Schuh A, Ledig C, Rueckert D, Soininen H, Remes AM, Waldemar G, Hasselbalch S, Mecocci P, van der Flier W, Lötjönen J. Differential diagnosis of neurodegenerative diseases using structural MRI data. Neuroimage Clin 2016:11:435-49.
18 Koivisto A. Alzheimerin taudin kokonaisvaltainen hoito. Best Practice Psykiatria/Neurologia 2016:4(13):16-19.
19 Koivisto AM, Hallikainen I, Välimäki T, Hongisto K, Hiltunen A, Karppi P, Sivenius J, Soininen H, Martikainen J. Early psychosocial intervention does not delay institutionalization in persons with mild Alzheimer disease and has impact on neither disease progression nor caregivers' well-being: ALSOVA 3-year follow-up. Int J Geriatr Psychiatry 2016:31(3):273-83.
20 Koivisto AM, Kurki MI, Alafuzoff I, Sutela A, Rummukainen J, Savolainen S, Vanninen R, Jääskeläinen JE, Soininen H, Leinonen V. High Risk of Dementia in Ventricular Enlargement with Normal Pressure Hydrocephalus Related Symptoms1. J Alzheimer Dis 2016:52(2):497-507.
21 Kulmala J, Ngandu T, Pajala S, Lehtisalo J, Levälahti E, Antikainen R, Laatikainen T, Oksa H, Peltonen M, Rauramaa R, Soininen H, Strandberg T, Tuomilehto J, Kivipelto M. Leisure-Time and Occupational Physical Activity in Early and Late Adulthood in Relation to Later Life Physical Functioning. J Phys Act Health 2016:13(10):1079-1087.
22 Kurkinen KMA, Marttinen M, Turner L, Natunen T, Mäkinen P, Haapalinna F, Sarajärvi T, Gabbouj S, Kurki M, Paananen J, Koivisto AM, Rauramaa T, Leinonen V, Tanila H, Soininen H, Lucas FR, Haapasalo A, Hiltunen M. SEPT8 modulates ß-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1. J Cell Sci 2016:129(11):2224-38.
23 Kälviäinen R. Unverricht-Lundborgin tauti. Epilepsia-lehti 2016(3):7-9.
24 Kälviäinen R, Bendel S, Jonsson H, Keränen T, Kurola J, Salmi T, Tuunainen A. Epileptinen kohtaus (pitkittynyt; status epilepticus). Käypä hoito -suositus (päivitystiivistelmä). Duodecim 2016:132(15):1385-1386.
25 Kälviäinen R, Genton P, Andermann E, Andermann F, Magaudda A, Frucht SJ, Schlit AF, Gerard D, de la Loge C, von Rosenstiel P. Brivaracetam in Unverricht-Lundborg disease (EPM1): Results from two randomized, double-blind, placebo-controlled studies. Epilepsia (NY) 2016:57(2):210-221.
26 Kälviäinen R, Järviseutu-Hulkkonen M, Keränen T, Rantala H. Epilepsia. Helsinki: Duodecim, 2016. Hyvä hoito -sarja. 224 s.
27 Lehtisalo J, Lindström J, Ngandu T, Kivipelto M, Ahtiluoto S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Eriksson JG, Uusitupa M, Tuomilehto J, Luchsinger JA. Diabetes, glycaemia, and cognition-a secondary analysis of the Finnish Diabetes Prevention Study. Diabetes Metab Res Rev 2016:32(1):102-10.
28 Lelental N, Brandner S, Kofanova O, ..., Herukka SK, ..., Lewczuk P. Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics. J Alzheimer Dis 2016:52(1):51-64.
29 Leuzy A, Chiotis K, Hasselbalch SG, ..., Herukka SK, ..., Nordberg A. Pittsburgh compound B imaging and cerebrospinal fluid amyloid-? in a multicentre European memory clinic study. Brain 2016:139(Pt 9):2540-53.
30 Lindner P, Savic I, Sitnikov R, Budhiraja M, Liu Y, Jokinen J, Tiihonen J, Hodgins S. Conduct disorder in females is associated with reduced corpus callosum structural integrity independent of comorbid disorders and exposure to maltreatment. Transl Psychiatry 2016:6:e714.
31 Luikku AJ, Hall A, Nerg O, Koivisto AM, Hiltunen M, Helisalmi S, Herukka SK, Sutela A, Kojoukhova M, Mattila J, Lötjönen J, Rummukainen J, Alafuzoff I, Jääskeläinen JE, Remes AM, Soininen H, Leinonen V. Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus. Acta Neurochir (Wien) 2016:158(12):2311-2319.
32 Lupton MK, Strike L, Hansell NK, ..., Soininen H, ..., Wright MJ. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume. Neurobiol Aging 2016:40:68-77.
33 Michelucci R, Pasini E, Riguzzi P, Andermann E, Kälviäinen R, Genton P. Myoclonus and seizures in progressive myoclonus epilepsies: pharmacology and therapeutic trials. Epileptic Dis 2016:18(S2):145-153.
34 Miller A-M, Rutkowska A, Bahl JM, Herukka S-K, Koel-Simmelink MJA, Kruse N, Mollenhauer B, Siloaho M, Skinningsrud A, Zetterberg H, Teunissen CE, Lawlor BA. Multicenter immunoassay validation of cerebrospinal fluid neurofilament light: a biomarker for neurodegeneration. Bioanalysis 2016:8(21):2243-2254.
35 Mouthaan BE, Rados M, Barsi P, ..., Kalviainen R, ..., Braun KPJ, on behalf of the E-PILEPSY consortium. Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe. Epilepsia (NY) 2016:57(5):770-6.
36 Muñoz-Ruiz MÁ, Hall A, Mattila J, Koikkalainen J, Herukka S-K, Husso M, Hänninen T, Vanninen R, Liu Y, Hallikainen M, Lötjönen J, Remes AM, Alafuzoff I, Soininen H, Hartikainen P. Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease. Dement Geriatr Cogn Disord Extra 2016:6(2):313-329.
37 Oeckl P, Jardel C, Salachas F, ..., Herukka S-K, ..., Otto M. Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS. Amyotroph Lateral Scler Frontotemp Degenerat 2016:17(5-6):404-413.
38 Orellana C, Ferreira D, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E, for the AddNeuronMed consortium , and for the Alzheimer's Disease Neuroimaging Initiative. Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations. Neurodegenerative Dis 2016:16(1-2):77-86.
39 Pereira JB, Mijalkov M, Kakaei E, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Spenger C, Lovestone S, Simmons A, Wahlund LO, Volpe G, Westman E. Disrupted network topology in patients with stable and progressive mild cognitive impairment and Alzheimer's disease. Cereb Cortex 2016:26(8):3476-3493.
40 Reuber M, Helmstaedter C, Liao W, Loddenkemper T, Thomas R, Kälviäinen R, Mann M. The future of medicine will be dark without international collaboration. Editorial. Seizure 2016:41:42.
41 Richard E, Jongstra S, Soininen H, Brayne C, Moll van Charante EP, Meiller Y, van der Groep B, Beishuizen CR, Mangialasche F, Barbera M, Ngandu T, Coley N, Guillemont J, Savy S, Dijkgraaf MG, Peters RJ, van Gool WA, Kivipelto M, Andrieu S. Healthy Ageing Through Internet Counselling in the Elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment. BMJ Open 2016:6(6):e010806.
42 Salminen A, Jouhten P, Sarajärvi T, Haapasalo A, Hiltunen M. Hypoxia and GABA shunt activation in the pathogenesis of Alzheimer's disease. Neurochem Int 2016:92:13-24.
43 Sattlecker M, Khondoker M, Proitsi P, Williams S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Dobson RJB. Longitudinal Protein Changes in Blood Plasma Associated with the Rate of Cognitive Decline in Alzheimer's Disease. J Alzheimer Dis 2016:49(4):1105-14.
44 Simonsen AH, Kuiperij B, El-Agnaf OM, Engelborghs S, Herukka S-K, Parnetti L, Rektorova I, Vanmechelen E, Kapaki E, Verbeek M, Mollenhauer B. The utility of a-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature. Biomark Med 2016:10(1):19-34.
45 Taina M, Vanninen R, Sipola P, Muuronen A, Jäkälä P, Hedman M. Cardiac CT Differentiates Left Atrial Appendage Thrombi from Circulatory Stasis in Acute Stroke Patients. In Vivo 2016:30(5):671-6.
46 Törmälehto S, Bell SJ, Väätäinen S, Hallikainen I, Koivisto A, Martikainen J. Alzheimerin taudin lääkehoito, sen muutokset ja kustannukset pitkäaikaisseurannassa: yhteys kognitiiviseen suoriutumiseen, toimintakykyyn ja käytösoireisiin - ALSOVA seurantatutkimus. Kirjassa: Mäklin S, toim. Terveystaloustiede 2016, työpaperi 1/2016, s. 16-19. Tampere: Terveyden ja hyvinvoinnin laitos, 2016.
47 Voyle N, Keohane A, Newhouse S, Lunnon K, Johnston C, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A, Kiddle S, Dobson RJB. A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis. J Alzheimer Dis 2016:49(3):659-69.
48 Välimäki TH, Martikainen JA, Hongisto K, Väätäinen S, Sintonen H, Koivisto AM. Impact of Alzheimer's disease on the family caregiver's long-term quality of life: results from an ALSOVA follow-up study. Qual Life Res 2016:25(3):687-97.
49 Väätäinen S, Hongisto K, Välimäki T, Hallikainen I, Koivisto A, Martikainen J. Alzheimerin tautia sairastavan potilaan ja tämän omaishoitajan elämänlaatu suhteessa sairauden vaikeusasteeseen - ALSOVA seurantatutkimus. Kirjassa: Mäklin S, toim. Terveystaloustiede 2016, työpaperi 1/2016, s. 13-15. Tampere: Terveyden ja hyvinvoinnin laitos, 2016.
50 Yan X, Nykänen N, Brunello CA, Haapasalo A, Hiltunen M, Uronen RL, Huttunen HJ. FRMD4A-cytohesin signaling modulates the cellular release of tau. J Cell Sci 2016:129(10):2003-15.
51 Zwan MD, Rinne JO, Hasselbach SG, Nordberg A, Lleó A, Herukka S-K, Soininen H, Law I, Bahl JMC, Carter SF, Fortea J, Blesa R, Teunissen CE, Bouwman FH, van Berckel BNM, Visser PJ. Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study. Neurology 2016:86(1):50-8.

Neurologian yksikkö Department of Neurology
Julkaisutietokanta 5.12.2019 Publications Data Base 5.12.2019