Kliininen kemia
Clinical Chemistry

Julkaisut 2018 (alustava)
Publications 2018 (preliminary)

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1 Akbaraly T et al. Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies.
2 Ampuja M, Kallioniemi A. Transcription factors-Intricate players of the bone morphogenetic protein signaling pathway.
3 Andre K et al. BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression.
4 Angeli A et al. Activation studies with amines and amino acids of the ß-carbonic anhydrase from the pathogenic protozoan Leishmania donovani chagasi.
5 Angeli A et al. Activation studies with amines and amino acids of the a-carbonic anhydrase from the pathogenic protozoan Trypanosoma cruzi.
6 Antenucci L et al. Phosphorylated immunoreceptor tyrosine-based activation motifs and integrin cytoplasmic domains activate spleen tyrosine kinase via distinct mechanisms.
7 Aspatwar A et al. Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes.
8 Aspatwar A et al. Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial ß-Carbonic Anhydrases: An Update on In Vitro and In Vivo Studies. Molecules.
9 Aspatwar A et al. An Update on the Metabolic Roles of Carbonic Anhydrases in the Model Alga Chlamydomonas reinhardtii.
10 Barrios C et al. Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations.
11 Bhosale S et al. Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis.
12 Bihlmeyer NA et al. ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals.
13 Boer DE S et al. The European Collaborative Project on Inflammation and Vascular Wall Remodeling in Atherosclerosis - Intravascular Ultrasound (ATHEROREMO-IVUS) study.
14 Brainstorm Consortium et al. Analysis of shared heritability in common disorders of the brain.
15 Bua S et al. Sulfonamide Inhibition Studies of a New ß-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica.
16 Buscot M et al. BMI Trajectories Associated With Resolution of Elevated Youth BMI and Incident Adult Obesity.
17 Buscot M et al. Distinct child-to-adult body mass index trajectories are associated with different levels of adult cardiometabolic risk.
18 Campbell M et al. Impact of Ideal Cardiovascular Health in Childhood on the Retinal Microvasculature in Midadulthood: Cardiovascular Risk in Young Finns Study.
19 Davies G et al. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
20 Delcourt C et al. The decreasing prevalence of nonrefractive visual impairment in older Europeans: a meta-analysis of published and unpublished data. .
21 Demenais F et al. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
22 Dobewall H et al. Oxytocin receptor gene (OXTR) variant rs1042778 moderates the influence of family environment on changes in perceived social support over time.
23 Dobewall H et al. The role of oxytocin receptor gene (OXTR) and mother's emotional warmth in predicting adulthood sociability.
24 Emameh Reza Z et al. Surveillance and diagnosis of zoonotic foodborne parasites .
25 Erhart G et al. Genetic Factors Explain a Major Fraction of the 50% Lower Lipoprotein(a) Concentrations in Finns.
26 Evangelou E et al. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
27 Feitosa M et al. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
28 Franceschini N et al. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
29 Gormley P et al. Common variant burden contributes to the familial aggregation of migraine in 1,589 families.
30 Gormley P et al. Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families.
31 Haapanen S et al. Cloning, Characterization and Anion Inhibition Studies of a ß-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica.
32 Haapasalo J et al. NRF2, DJ1 and SNRX1 and their prognostic impact in astrocytic gliomas.
33 Haining A et al. Mechanotransduction in talin through the interaction of the R8 domain with DLC1.
34 Haworth S et al. Consortium-based genome-wide meta-analysis for childhood dental caries traits.
35 Hernesniemi J et al. Aortic sinus diameter in middle age is associated with body size in young adulthood.
36 Huang T et al. Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies.
37 Högnäs G et al. Feasibility of Prostate PAXgene Fixation for Molecular Research and Diagnostic Surgical Pathology: Comparison of Matched Fresh Frozen, FFPE, and PFPE Tissues.
38 Immonen H et al. Increased Liver Fatty Acid Uptake Is Partly Reversed and Liver Fat Content Normalized After Bariatric Surgery.
39 Jackson V et al. Meta-analysis of exome array data identifies six novel genetic loci for lung function.
40 Jiang X et al. Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.
41 Kaikkonen E et al. ANO7 is associated with aggressive prostate cancer.
42 Kallio H et al. Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases.
43 Karjalainen S et al. Carbonic anhydrase related protein expression in astrocytomas and oligodendroglial tumors.
44 Kartasalo K et al. Comparative analysis of tissue reconstruction algorithms for 3D histology.
45 Kettunen J et al. Biomarker Glycoprotein Acetyls Is Associated With the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients.
46 Khan N et al. Extended Serum Lipid Profile Predicting Long-Term Survival in Patients Treated for Abdominal Aortic Aneurysms.
47 Koivistoinen T et al. Pulse Wave Velocity Predicts the Progression of Blood Pressure and Development of Hypertension in Young Adults.
48 Koivusalo L et al. Digital image analysis of the tissue surface areas of site-designated and bilaterally pooled prostate biopsies.
49 Komulainen K et al. Education as a moderator of genetic risk for higher body mass index: prospective cohort study from childhood to adulthood.
50 Kukkurainen S. Molecular dynamics of talin-integrin interaction.
51 Kunnas T et al. Association of a Chromosome Locus 9p21.3 CDKN2B-AS1 Variant rs4977574 with Hypertension: The TAMRISK Study.
52 Kunnas T et al. Gene polymorphisms of fibronectin rs2289202 and fibrillin 2 rs331069 associate with vascular disease, the TAMRISK study.
53 Kunnas T et al. Association of low-density lipoprotein receptor-related protein 1 rs11613352 and angiopoietin-like 3 rs2131925 with hypertension in men-the Tampere adult population cardiovascular risk study.
54 Laitinen OH et al. New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.
55 Latonen L et al. Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression.
56 Latonen L et al. Proteomics of prostate cancer - revealing how cancer cells master their messy genomes.
57 Lee J et al. Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
58 Leppänen J et al. Toll-like receptors 2, 4 and 9 and hypoxia markers HIF-1alpha and CAIX in pancreatic intraepithelial neoplasia. .
59 Leppänen J et al. Weak HIF-1alpha expression indicates poor prognosis in resectable pancreatic ductal adenocarcinoma.
60 Ligthart S et al. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
61 Lin H et al. Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval.
62 Luhtala S et al. Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4-1 and NRDP1, in primary breast cancer.
63 Luukinen H et al. Priming of innate antimycobacterial immunity by heat-killed Listeria monocytogenes induces sterilizing response in the adult zebrafish tuberculosis model.
64 Mauschitz MM et al. Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population.
65 Mckeown NM et al. Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis.
66 McNair C et al. Differential impact of RB status on E2F1 reprogramming in human cancer.
67 Mykuliak V et al. Mechanical unfolding reveals stable 3-helix intermediates in talin and a-catenin.
68 Ncd RISK Factor Collaboration et al. Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.
69 Nissinen M et al. Genetic polymorphism of sterol transporters in children with future gallstones.
70 Nordfors K et al. Whole-exome sequencing identifies germline mutation in TP53 and ATRX in a child with genomically aberrant AT/RT and her mother with anaplastic astrocytoma.
71 Nortunen M et al. Carbonic anhydrases II, IX, and XII in Barrett's esophagus and adenocarcinoma.
72 Nurminen A, Hytönen V. StructureMapper: a high-throughput algorithm for analyzing protein sequence locations in structural data.
73 Oksman E et al. A Longitudinal Multilevel Study of the "Social" Genotype and Diversity of the Phenotype.
74 Ozsait-Selcuk B et al. The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study.
75 Parkkila S et al. Aineenvaihduntasairaudet.
76 Parmar P et al. Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults.
77 Parveen N et al. Membrane Deformation Induces Clustering of Norovirus Bound to Glycosphingolipids in a Supported Cell-Membrane Mimic.
78 Piesanen J et al. Association of Desmin Gene Variant rs1058261 with Cardiovascular Disease, the TAMRISK Study.
79 Prins B et al. Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.
80 Pyysalo M et al. The dental infections in patients undergoing preoperative dental examination before surgical treatment of saccular intracranial aneurysm.
81 Qi T et al. Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood.
82 Ranta N et al. Proprotein convertase enzyme FURIN is upregulated in primary Sjögren's syndrome.
83 Rimpelä J et al. Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients.
84 Rinne P et al. Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation.
85 Rinne P et al. Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis - Tampere Vascular Study.
86 Rosselli C et al. Multi-ethnic genome-wide association study for atrial fibrillation.
87 Saarinen A et al. The co-occurrence between depressive symptoms and paranoid ideation: A population-based longitudinal study.
88 Saarinen A et al. Longitudinal Associations of Explosive and Adventurous Temperament Profiles With Character Development: The Modifying Effects of Social Support and Attachment.
89 Saarinen A et al. Longitudinal associations of temperament and character with paranoid ideation: A population-based study.
90 Saarinen N et al. A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.
91 Salmela M et al. Molecular tools for selective recovery and detection of lignin-derived molecules.
92 Saviauk T et al. Electronic Nose in the Detection of Wound Infection Bacteria from Bacterial Cultures: A Proof-of-Principle Study.
93 Schnurr TM et al. Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children.
94 Shao D et al. Surface Characteristics Control the Attachment and Functionality of (Chimeric) Avidin.
95 Sioofy-Khojine A et al. Molecular epidemiology of enteroviruses in young children at increased risk of type 1 diabetes.
96 Sliz E et al. NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects.
97 Smith C et al. Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent.
98 Solismaa A et al. Genetic Polymorphisms Associated With Constipation and Anticholinergic Symptoms in Patients Receiving Clozapine.
99 Stone V et al. A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.
100 Sun C et al. Childhood adiposity, adult adiposity, and the ACE gene insertion/deletion polymorphism: evidence of gene-environment interaction effects on adult blood pressure and hypertension status in adulthood.
101 Sung Y et al. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
102 Taipale T et al. Fatty liver is associated with blood pathways of inflammatory response, immune system activation and prothrombotic state in Young Finns Study.
103 Takeuchi F et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
104 Tapio K et al. A DNA-nanoparticle actuator enabling optical monitoring of nanoscale movements induced by an electric field.
105 Tapp R et al. Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study.
106 Tedja M et al. Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.
107 Tolonen S et al. Higher step count is associated with greater bone mass and strength in women but not in men.
108 Toompuu M et al. Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells.
109 Trajanoska K et al. Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.
110 Turcot V et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
111 Tynkkynen J et al. Association of branched-chain amino acids and other circulating.
112 Vakhitov D et al. Bacterial signatures in thrombus aspirates of patients with lower limb arterial and venous thrombosis.
113 Van Setten J et al. PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.
114 Venäläinen MK et al. Altered Polyamine Profiles in Colorectal Cancer.
115 Veskimäe K et al. Expression Analysis of Platinum Sensitive and Resistant Epithelial Ovarian Cancer Patient Samples Reveals New Candidates for Targeted Therapies.
116 Viinikainen J et al. Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization.
117 Vistbakka J et al. Evaluation of serum miR-191-5p, miR-24-3p, miR-128-3p, and miR-376c-3 in multiple sclerosis patients.
118 Vullo D et al. Anion inhibition studies of a beta carbonic anhydrase from the malaria mosquito Anopheles gambiae.
119 Vuorinen EM et al. Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells.
120 Wedge D et al. Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
121 Wu F et al. Both youth and long-term vitamin D status is associated with risk of type 2 diabetes mellitus in adulthood: a cohort study.
122 Xue A et al. Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
123 Yang Y et al. Molecular genetic overlap between migraine and major depressive disorder.
124 Zhou A et al. Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.
125 Zolfaghari Emameh R et al. Involvement of ß-Carbonic Anhydrase Genes in Bacterial Genomic Islands and Their Horizontal Transfer to Protists.
Kliininen kemia Clinical Chemistry
Julkaisutietokanta 31.12.2019 Publications Data Base 31.12.2019