Kliinisen fysiologian ja isotooppilääketieteen yksikkö
Department of Clinical Physiology and Nuclear Medicine

Julkaisut 2019 (alustava)
Publications 2019 (preliminary)

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1 Ahola-Olli A et al. Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts.
2 Birth-Gene (BIG) Study Working Group et al. Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.
3 Bradfield J et al. A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.
4 Choudhary M et al. LDL cholesterol is associated with systemic vascular resistance and wave reflection in subjects naive to cardiovascular drugs.
5 Choudhary MK et al. Atherogenic index of plasma is related to arterial stiffness but not to blood pressure in normotensive and never-treated hypertensive subjects.
6 Davies G et al. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
7 Deelen J et al. A meta-analysis of genome-wide association studies identifies multiple longevity genes.
8 Dörr M et al. Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation.
9 Evangelou E et al. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.
10 Halonen J et al. Exposure to heavy physical work from early to later adulthood and primary healthcare visits due to musculoskeletal diseases in midlife: a register linked study.
11 Hautaniemi E et al. Liquorice ingestion attenuates vasodilatation via exogenous nitric oxide donor but not via ß2-adrenoceptor stimulation.
12 Heiskanen JS et al. Determinants of left ventricular diastolic function-The Cardiovascular Risk in Young Finns Study.
13 Juonala M et al. Childhood Exposure to Passive Smoking and Bone Health in Adulthood: The Cardiovascular Risk in Young Finns Study.
14 Kangas P et al. Changes in hemodynamics associated with metabolic syndrome are more pronounced in women than in men.
15 Kangas P et al. Metabolic syndrome is associated with decreased heart rate variability in a sex-dependent manner: a comparison between 252 men and 249 women.
16 Karjalainen J et al. New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults.
17 Karjalainen J et al. The effect of apolipoprotein E polymorphism on serum metabolome - a population-based 10-year follow-up study.
18 Karlsson Linnér R et al. Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
19 Kettunen J et al. Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.
20 Komulainen K et al. Socioeconomic position and intergenerational associations of ideal health behaviors.
21 Komulainen K et al. Childhood Psychosocial Environment and Adult Cardiac Health: A Causal Mediation Approach.
22 Koskela H et al. Epäsuorat altistuskokeet astman diagnosoinnissa.
23 Laaksonen J et al. Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study.
24 Lamina C et al. Estimation of the Required Lipoprotein(a)-Lowering Therapeutic Effect Size for Reduction in Coronary Heart Disease Outcomes: A Mendelian Randomization Analysis.
25 Lea A et al. Genetic and environmental perturbations lead to regulatory decoherence.
26 Mendelian Randomization of Dairy Consumption Working Group Charge Consortium et al. Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies.
27 Merino J et al. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
28 Middeldorp C et al. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.
29 Mononen N et al. Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.
30 Murphy A et al. Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta-Analysis of 19 005 Individuals.
31 Nath A et al. Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.
32 Noordam R et al. Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals.
33 Nynäs P et al. Observational cross-sectional study on Symptoms Associated to Moisture DAmage at Workplace: the SAMDAW study protocol.
34 Patel R et al. Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.
35 Patel R et al. Subsequent Event Risk in Individuals With Established Coronary Heart Disease.
36 Porcu E et al. Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits.
37 Pussinen P et al. Association of Childhood Oral Infections With Cardiovascular Risk Factors and Subclinical Atherosclerosis in Adulthood.
38 Rimpelä JM et al. Genome-wide association study of white-coat effect in hypertensive patients.
39 Sakornsakolpat P et al. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
40 Salokari E et al. The Duke treadmill score with bicycle ergometer: Exercise capacity is the most important predictor of cardiovascular mortality.
41 Shrine N et al. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
42 Sipilä K et al. Combination of low blood pressure response, low exercise capacity and slow heart rate recovery during an exercise test significantly increases mortality risk.
43 Spracklen CN et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
44 Stahl EA et al. Genome-wide Association Study Identifies 30 Loci Associated With Bipolar Disorder.
45 Tabassum R et al. Genetic architecture of human plasma lipidome and its link to cardiovascular disease.
46 Teumer A et al. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
47 Tikkakoski AP et al. Association of air humidity with incidence of exercise-induced bronchoconstriction in children.
48 Timmers PR et al. Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances.
49 Tin A et al. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
50 Tuominen H et al. 18F-FDG-PET in Finnish patients with clinical suspicion of cardiac sarcoidosis: Female sex and history of atrioventricular block increase the prevalence of positive PET findings.
51 Viitasalo A et al. Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis.
52 Viitasalo A et al. Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents.
53 Vähämurto L et al. Coronary heart disease risk factor levels in eastern and western Finland from 1980 to 2011 in the cardiovascular risk in Young Finns study.
54 Warrington NM et al. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.
55 Wu F et al. Youth and Long-Term Dietary Calcium Intake With Risk of Impaired Glucose Metabolism and Type 2 Diabetes in Adulthood.
56 Wuttke M et al. A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Kliinisen fysiologian ja isotooppilääketieteen yksikkö Department of Clinical Physiology and Nuclear Medicine
Julkaisutietokanta 31.12.2020 Publications Data Base 31.12.2020