Kliininen kemia
Clinical Chemistry

Julkaisut 2019 (alustava)
Publications 2019 (preliminary)

Lisätietoja julkaisusta saa klikkaamalla sen numeroa.
For full details, please click the number in front of the publication.

1 Adlam D et al. Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.
2 Agrawal N et al. Molecular features of steroid-binding antidins and their use for assaying serum progesterone.
3 Ahola-Olli A et al. Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts.
4 Al-Tamimi AS et al. Discovery of new organoselenium compounds as antileishmanial agents.
5 Aspatwar A et al. Carbonic anhydrases from pathogens: protozoan CAs and related inhibitors as potential antiprotozoal agents.
6 Aspatwar A et al. Rapid Evaluation of Toxicity of Chemical Compounds Using Zebrafish Embryos.
7 Aspatwar A et al. Mycobacterium tuberculosis ß-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs.
8 Aspatwar A et al. Catalytically inactive carbonic anhydrase-related proteins enhance transport of lactate by MCT1.
9 Assel M et al. A Four-kallikrein Panel and ß-Microseminoprotein in Predicting High-grade Prostate Cancer on Biopsy: An Independent Replication from the Finnish Section of the European Randomized Study of Screening for Prostate Cancer.
10 Bachmann M et al. Cell Adhesion by Integrins.
11 Basnyat P et al. Gene expression profiles of TNF-like cytokine 1A (TL1A) and its receptors death receptor 3 (DR3) and decoy receptor 3 (DcR3) in multiple sclerosis.
12 Bentley AR et al. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
13 Birth-Gene (BIG) Study Working Group et al. Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.
14 Bradfield J et al. A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.
15 Bua S et al. Activation Studies of the -Carbonic Anhydrase from the Pathogenic Protozoan .
16 Böckerman P et al. The effect of weight on labor market outcomes: An application of genetic instrumental variables.
17 Chauhan G et al. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
18 Colijn JM et al. Increased High-Density Lipoprotein Levels Associated With Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia .
19 Davies G et al. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
20 de Vries PS et al. Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
21 Deelen J et al. A meta-analysis of genome-wide association studies identifies multiple longevity genes.
22 Dobewall H et al. Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study.
23 Dörr M et al. Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation.
24 Eerola S et al. Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion.
25 Evangelou E et al. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.
26 Fan Y et al. High prevalence of selected viruses and parasites and their predictors in Malawian children.
27 Fiorito G et al. Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.
28 Gadina M et al. Janus kinases to jakinibs: from basic insights to clinical practice.
29 Gattoussi S et al. The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies.
30 Gering C et al. Design of modular gellan gum hydrogel functionalized with avidin and biotinylated adhesive ligands for cell culture applications.
31 Gluschkoff K et al. Is It Good To Be Good? Dispositional Compassion and Health Behaviors.
32 Halonen J et al. Exposure to heavy physical work from early to later adulthood and primary healthcare visits due to musculoskeletal diseases in midlife: a register linked study.
33 Hammarén H et al. Janus kinase 2 activation mechanisms revealed by analysis of suppressing mutations.
34 Hammarén H et al. The regulation of JAKs in cytokine signaling and its breakdown in disease.
35 Hankaniemi M et al. A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine.
36 Hankaniemi MM et al. Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine.
37 Heinimäki S et al. Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus.
38 Heiskanen JS et al. Determinants of left ventricular diastolic function-The Cardiovascular Risk in Young Finns Study.
39 Hernesniemi J et al. Extensive phenotype data and machine learning in prediction of mortality in acute coronary syndrome - the MADDEC study.
40 Holvoet P et al. RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease.
41 Iverson GL et al. Mild Chronic Traumatic Encephalopathy Neuropathology in People With No Known Participation in Contact Sports or History of Repetitive Neurotrauma.
42 Jia Q et al. Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease.
43 Juonala M et al. Childhood Exposure to Passive Smoking and Bone Health in Adulthood: The Cardiovascular Risk in Young Finns Study.
44 Justice AE et al. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
45 Karjalainen J et al. New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults.
46 Karjalainen J et al. The effect of apolipoprotein E polymorphism on serum metabolome - a population-based 10-year follow-up study.
47 Karlsson Linnér R et al. Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
48 Kazokaite J et al. Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors.
49 Keeble A et al. Approaching infinite affinity through engineering of peptide-protein interaction.
50 Ketomäki T et al. R-Ras regulates vascular permeability, but not overall healing in skin wounds.
51 Kettunen J et al. Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.
52 Kilpeläinen TO et al. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
53 Kortekangas E et al. A Prospective Study on Child Morbidity and Gut Microbiota in Rural Malawi.
54 Laajala M et al. Host Cell Calpains Can Cleave Structural Proteins from the Enterovirus Polyprotein.
55 Laaksonen J et al. Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study.
56 Lamina C et al. Estimation of the Required Lipoprotein(a)-Lowering Therapeutic Effect Size for Reduction in Coronary Heart Disease Outcomes: A Mendelian Randomization Analysis.
57 Latva-Rasku A et al. The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients.
58 Lea A et al. Genetic and environmental perturbations lead to regulatory decoherence.
59 Lehtomäki K et al. Clonal Evolution of MEK/MAPK Pathway Activating Mutations in a Metastatic Colorectal Cancer Case.
60 Lemma T et al. Identifying yeasts using surface enhanced Raman spectroscopy.
61 Lempiäinen J et al. Haptoglobin Hp1 Variant Does Not Associate with Small Vessel Disease.
62 Levy A et al. National MEDigi project: systematic implementation of digitalization to undergraduate medical and dental education in Finland.
63 Liu X et al. Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.
64 Luoma S et al. RVD induction and autologous stem cell transplantation followed by lenalidomide maintenance in newly diagnosed multiple myeloma: a phase 2 study of the Finnish Myeloma Group.
65 Lähdeaho ML et al. Safety and efficacy of AMG 714 in adults with coeliac disease exposed to gluten challenge: a phase 2a, randomised, double-blind, placebo-controlled study.
66 Mandaviya PR et al. Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals.
67 Mendelian Randomization of Dairy Consumption Working Group Charge Consortium et al. Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies.
68 Merino J et al. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
69 Middeldorp C et al. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.
70 Minkkinen M et al. Prospective Validation of the Scandinavian Guidelines for Initial Management of Minimal, Mild, and Moderate Head Injuries in Adults.
71 Mononen N et al. Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.
72 Murphy A et al. Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta-Analysis of 19 005 Individuals.
73 Nath A et al. Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.
74 NCD Risk Factor Collaboration (NCD-RisC) et al. Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative surveys.
75 Ncd RISK Factor Collaboration Ncd-risc et al. Rising rural body-mass index is the main driver of the global obesity epidemic in adults.
76 Nissinen SI et al. Detection of Pancreatic Cancer by Urine Volatile Organic Compound Analysis.
77 Noordam R et al. Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.
78 Noordam R et al. Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals.
79 Nurmi A et al. Recurrent moderate-risk mutations in Finnish breast and ovarian cancer patients.
80 Parveen N et al. Competition for Membrane Receptors: Norovirus Detachment via Lectin Attachment.
81 Patel R et al. Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.
82 Patel R et al. Subsequent Event Risk in Individuals With Established Coronary Heart Disease.
83 Patrakka O et al. Oral Bacterial Signatures in Cerebral Thrombi of Patients With Acute Ischemic Stroke Treated With Thrombectomy.
84 Patrikainen M. Carbonic Anhydrase VI : Functional characterization in mouse and zebrafish model organisms.
85 Pehkonen J et al. Health endowment and later-life outcomes in the labour market: Evidence using genetic risk scores and reduced-form models.
86 Porcu E et al. Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits.
87 Poukka M et al. Acute Lymphoblastic Leukemia With INPP5D-ABL1 Fusion Responds to Imatinib Treatment.
88 Puura K et al. Maternal and infant characteristics connected to shared pleasure in dyadic interaction.
89 Pyysalo MJ et al. Increased tooth brushing frequency is associated with reduced gingival pocket bacterial diversity in patients with intracranial aneurysms.
90 Rahikainen R et al. Talin-mediated force transmission and talin rod domain unfolding independently regulate adhesion signaling.
91 Raivola J et al. Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling.
92 Rimpelä JM et al. Genome-wide association study of white-coat effect in hypertensive patients.
93 Saari S et al. Alternative oxidase confers nutritional limitation on Drosophila development.
94 Saarinen A et al. The relationship of dispositional compassion for others with depressive symptoms over a 15-year prospective follow-up.
95 Saghafi T et al. Phytochemicals as Modulators of Long Non-Coding RNAs and Inhibitors of Cancer-Related Carbonic Anhydrases.
96 Sakornsakolpat P et al. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
97 Salokari E et al. The Duke treadmill score with bicycle ergometer: Exercise capacity is the most important predictor of cardiovascular mortality.
98 Satomaa A et al. The intraoperative laryngeal adductor reflex (LAR) in brainstem tumor removal: A case of unilateral loss of LAR signal.
99 Satomaa AL et al. Reply to "Unforeseen clinical outcome for laryngeal adductor reflex loss during intraaxial brainstem surgery".
100 Savelieva K et al. The role of oxytocinergic genes in the intergenerational transmission of parent-child relationship qualities.
101 Savolainen A et al. Physical Activity Associates with Muscle Insulin Sensitivity Postbariatric Surgery.
102 Shrine N et al. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
103 Sipilä K et al. Combination of low blood pressure response, low exercise capacity and slow heart rate recovery during an exercise test significantly increases mortality risk.
104 Sivertsen EAndreas et al. No Association Between Risk of Anterior Cruciate Ligament Rupture and Selected Candidate Collagen Gene Variants in Female Elite Athletes From High-Risk Team Sports.
105 Sliz E et al. Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns.
106 Soto-Ribeiro M et al. ß1D integrin splice variant stabilizes integrin dynamics and reduces integrin signaling by limiting paxillin recruitment.
107 Spracklen CN et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
108 Stahl EA et al. Genome-wide Association Study Identifies 30 Loci Associated With Bipolar Disorder.
109 Sung YJ et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
110 Syyli N et al. Left ventricular ejection fraction adds value over the GRACE score in prediction of 6-month mortality after ACS: the MADDEC study.
111 T Virtanen A et al. Selective JAKinibs: Prospects in Inflammatory and Autoimmune Diseases.
112 Talvitie E et al. Adverse childhood environment and self-reported sleep in adulthood: The Young Finns Study.
113 Teumer A et al. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
114 Timmers PR et al. Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances.
115 Tin A et al. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
116 Tuomisto S et al. Age-dependent association of gut bacteria with coronary atherosclerosis: Tampere Sudden Death Study.
117 Törnroos M et al. Personality traits and perceptions of organisational justice.
118 Valli A et al. Increased expression of the proprotein convertase enzyme FURIN in rheumatoid arthritis.
119 van Setten J et al. Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
120 Viitasalo A et al. Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis.
121 Viitasalo A et al. Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents.
122 Vuorinen EM et al. Correction to: Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells.
123 Vähämurto L et al. Coronary heart disease risk factor levels in eastern and western Finland from 1980 to 2011 in the cardiovascular risk in Young Finns study.
124 Warrington NM et al. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.
125 Wu F et al. Youth and Long-Term Dietary Calcium Intake With Risk of Impaired Glucose Metabolism and Type 2 Diabetes in Adulthood.
126 Wuttke M et al. A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Kliininen kemia Clinical Chemistry
Julkaisutietokanta 31.12.2020 Publications Data Base 31.12.2020