Kuopion yliopistollinen sairaala
Kuopio University Hospital

Julkaisut 2013
Publications 2013

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1 Synnynnäisten ja perinnöllisten sydänsairauksien seuranta lapsilla ja aikuisilla. Finnish guidelines for following patients with hereditary heart diseases.
2 Aalto TJ. Preoperative predictors and postoperative outpatient rehabilitation of lumbar spinal stenosis.
3 Aartolahti E et al. Relationship between functional vision and balance and mobility performace in community dwelling older adults.
4 Aguilar C et al. Different multivariate techniques for automated classification of MRI data in Alzheimer´s disease and mild cognitive impairment.
5 Ahlqvist E et al. Link between GIP and osteopontin in adipose tissue and insulin resistance.
6 Ahonen J et al. Kliininen farmasia potilaan lääkehoidon tukena.
7 Ahonen J et al. Pitkäaikaispotilaiden lääkehoidon järkeistäminen palvelukeskuksessa.
8 Ahonen J et al. Lääkkeenoton järkevä ajoitus tehostaa vaikutusta.
9 Aira M et al. Hyvät kokemukset terveyskeskustyöstä ohjaavat erikoistumaan yleislääketieteeseen.
10 Airaksinen KE et al. Thromboembolic complications after cardioversion of acute atrial fibrillation - The FinCV (Finnish CardioVersion) study .
11 Airenne KJ et al. Baculovirus: an insect-derived vector for diverse gene transfer applications.
12 Albrechtsen A et al. Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.
13 Alekseeva LA et al. Can normal age-related changes in cartilage be distinguished from early osteoarthritic changes?
14 Antila K et al. The PredictAD project: development of novel biomarkers and analysis software for early diagnosis of the Alzheimer's disease.
15 Antonoglou G et al. Serum 1,25(OH)D level increases after elimination of periodontal inflammation in T1DM subjects.
16 Arokoski J, ... Tehostetusta itsehoidon ohjauksesta ei lisähyötyä käsinivelrikkopotilaille.
17 Arraut AM et al. Fetal pulmonary arterial vascular impedance reflects changes in fetal oxygenation at near-term gestation in a nonhuman primate model.
18 Auvinen P et al. Increased hyaluronan content and stromal cell CD44 associate with HER2 positivity and poor prognosis in human breast cancer.
19 Bach N et al. The effect of surgically assisted rapid maxillary expansion on sleep architecture: an exploratory risk study in healthy young adults.
20 Bell JS et al. Potentially inappropriate drug use among older persons in Finland: application of a new national categorization.
21 Berg LT, Jaakkola P. Kuopio treatment strategy after deep sternal wound infection.
22 Berndt SI et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
23 Blasiak J et al. Mitochondrial and nuclear DNA damage and repair in age-related macular degeneration.
24 Blasiak J et al. Potential of epigenetic mechanisms in AMD pathology.
25 Bojesen SE et al. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
26 Bonnycastle LL et al. Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation.
27 Borgnakke WS et al. Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence.
28 Brander P, Erkinjuntti-Pekkanen R. Toimintakyvyn arviointi keuhkosairauksissa.
29 Brummer TH et al. Antibiotic prophylaxis for hysterectomy, a prospective cohort study: cefuroxime, metronidazole, or both?
30 Carlberg C et al. Primary vitamin D target genes allow a categorization of possible benefits of vitamin D3 supplementation.
31 Carpén O, Kosma VM. Tutkimus tulevien potilaiden parhaaksi: patologia perustutkimuksen ja kliinisen tutkimuksen rajapinnassa.
32 Cederberg H et al. Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish men.
33 Chapple ILC et al. Diabetes and periodontal diseases: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases.
34 Chow BJ et al. Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project i-C).
35 Civelek M et al. Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits.
36 Clerx L et al. Measurements of medial temporal lobe atrophy for prediction of Alzheimer´s disease in subjects with mild cognitive impairment.
37 Coco K et al. Finnish nurses' views of support provided to families about traumatic brain injury patients' daily activities and care.
38 Coco K et al. The provision of emotional support to the families of traumatic brain injury patients: perspectives of finnish nurses.
39 Cornforth DJ et al. Using renyi entropy to detect early cardiac autonomic neuropathy.
40 Cowling D et al. Successful ageing and the capacity to thrive in old age: a review of the key elements.
41 Damian M et al. Single-domain amnestic mild cognitive impairment idenfied by cluster analysis predicts Alzheimer´s Disease in the European Prospective DESCRIPA Study.
42 Danner N et al. Alterations of motor cortical excitability and anatomy in Unverricht-Lundborg disease.
43 Deloukas P et al. Large-scale association analysis identifies new risk loci for coronary artery disease.
44 Dhungana H et al. Aging aggravates ischemic stroke-induced brain damage in mice with chronic peripheral infection.
45 Dhungana H et al. Western-type diet modulates inflammatory responses and impairs functional outcome following permanent middle cerebral artery occlusion in aged mice expressing the human apolipoprotein E4 allele.
46 Dietz A et al. Paediatric cochlear implantation surgery: surgical aspects and preliminary results on hearing preservation, electrode placement and performace with the cochlear nucleus CI422 implant.
47 Do R et al. Common variants associated with plasma triglycerides and risk for coronary artery disease.
48 Dragneva G et al. Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success.
49 Drzymala-Czyz S et al. Prevalence of Helicobacter pylori infection in patients with cystic fibrosis.
50 Elias-Sonnenschein LS et al. Genetic loci associated with Alzheimer´s Disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.
51 Elomaa AP et al. Self-reported sleep disturbance is associated with elevated levels of PAI-1 in individuals with a recorded history of depressive symptoms.
52 Erkinjuntti-Pekkanen R. Allerginen alveoliitti ja orgaanisten pölyjen aiheuttama toksinen oireyhtymä.
53 Erkinnaro T et al. Fetal cardiac function after labetalol or pindolol for maternal hypertension in a sheep model of increased placental vascular resistance.
54 Evans DM et al. Mining the human phenome using allelic scores that index biological intermediates.
55 Ezzat S et al. The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.
56 Fall T et al. The role of adiposity in cardiometabolic traits: A mendelian randomization analysis.
57 Fatemifar G et al. Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
58 French JD et al. Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.
59 Gagnon DD et al. Cold exposure enhances fat utilization but not non-esterified fatty acids, glycerol or catecholamines availability during submaximal walking and running.
60 Galanopoulou AS et al. Epilepsy therapy development: Technical and methodologic issues in studies with animal models.
61 Garcia-Closas M et al. Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
62 Gauffin J et al. Do fibromyalgia patients use active pain management strategies? A cohort study.
63 Gauffin J et al. Neuropathic pain and use of painDETECT in patients with fibromyalgia: a cohort study.
64 Giacco R et al. Effects of rye and whole wheat versus refined cereal foods on metabolic risk factors: A randomised controlled two-centre intervention study.
65 Glauser T et al. Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes.
66 Grönberg T et al. Arrhythmic complications after electrical cardioversion of acute atrial fibrillation: The FinCV study.
67 Guerreiro R et al. TREM2 variants in Alzheimer's disease.
68 Gurevicius K et al. Increased cortical and thalamic excitability in freely moving APPswe/PS1dE9 mice modeling epileptic activity associated with Alzheimer's disease.
69 Gursoy UK et al. Salivary type I collagen degradation end-products and related matrix metalloproteinases in periodontitis.
70 Haapasalo T et al. Peroxiredoxins and their expression in ependymomas.
71 Haikola B et al. Radiological signs indicating infection of dental origin in elderly Finns.
72 Halkoaho A et al. Education of research ethics for clinical investigators with Moodle tool.
73 Hallikainen I et al. Progression of Alzheimer's disease during a three-year follow-up using the CERAD-NB total score: Kuopio ALSOVA study.
74 Hallikainen M et al. Cholesterol metabolism and weight reduction in subjects with mild obstructive sleep apnoea: a randomised, controlled study.
75 Halonen J et al. Prevention of artrial fibrillation after cardiac surgery. Intravenous Metoprolol, Amiodarone and Hydrocortisone reduces the incidence of postoperative atrial fibrillation.
76 Halonen J et al. Prevention of atrial fibrillation after cardiac surgery. Intravenous metoprolol, amiodarone and hydrocortisone reduces the incidence of postoperative atrial fibrillation.
77 Halonen KS et al. Importance of depth-wise distribution of collagen and proteoglycans in articular cartilage--a 3D finite element study of stresses and strains in human knee joint.
78 Hammarstedt A et al. WISP2 regulates preadipocyte commitment and PPARy activation by BMP4.
79 Happo MS et al. Pulmonary inflammation and tissue damage in the mouse lung after exposure to PM samples from biomass heating appliances of old and modern technologies.
80 Harju J et al. Ten-year outcome after minilaparotomy versus laparoscopic cholecystectomy: a prospective randomised trial.
81 Harju J et al. Minilaparotomy cholecystectomy with ultrasonic dissection versus conventional laparoscopic cholecystectomy: a randomized multicenter study.
82 Harju M et al. Maternal fecundity and asthma among offspring - is the risk programmed preconceptionally? Retrospective observational study.
83 Hartikainen J. Sydäninfarktin hoidon tulokset ja kustannukset Suomessa.
84 Heikkilä HM et al. Combined low-saturated fat intake and high fitness may counterbalance diabetogenic effects of obesity: the DR's EXTRA Study.
85 Hein R et al. A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication.
86 Heiskanen TH et al. Depression and major weight gain: A 6-year prospective follow-up of outpatients.
87 Helin-Tanninen M. Compounding of paediatric oral formulations. Extemporaneous nifedipine capsules, powders and suspensions in the hospital pharmacy.
88 Helin-Tanninen M et al. Stability of an epidural analgesic admixture of levobupivacaine, fentanyl and epinephrine.
89 Heliö T, Kuusisto J. Kardiomyopatiat ja myokardiitti.
90 Heliövaara-Peippo S et al. Quality of life and costs of levonorgestrel-releasing intrauterine system or hysterectomy in the treatment of menorrhagia: a 10-year randomized controlled trial.
91 Hella P et al. Disordered semantic activation in disorganized discourse in schizophrenia: a new pragma-linguistic tool for structure and meaning reconstruction.
92 Helminen EE et al. Effectiveness of a cognitive-behavioral group intervention for knee osteoarthritis pain: protocol of a randomized controlled trial.
93 Helve O et al. Tutkijakoulut murroksessa - esimerkkinä Valtakunnallisen kliinisen tutkijakoulun tohtoriohjelma.
94 Hietamäki M. Elämänvaihelähtöinen henkilöstövoimavarojen johtaminen. Tutkimus lääkäreiden ja sairaanhoitajien työ- ja organisaatiositoutumisesta.
95 Hiltunen M et al. B-type natriuretic peptide and severity of cognitive disorder.
96 Hiltunen M et al. Alzheimerin taudin uudet riskigeenit - tautia ennakoivat biomarkkerit?
97 Hiltunen M et al. The prognostic capacity of B-type natriuretic peptide on cognitive disorder varies by age.
98 Hintsala HR et al. Claudins 1, 2, 3, 4, 5 and 7 in solar keratosis and squamocellular carcinoma of the skin.
99 Hirvasniemi J et al. In vivo comparison of delayed gadolinium-enhanced MRI of cartilage and delayed quantitative CT arthrography in imaging of articular cartilage.
100 Hong-Gu H, Vehviläinen-Julkunen K. Allying with Chinese parents for enhanced control of pediatric postoperative pain.
101 Horwich A et al. Prostate cancer: ESMO consensus conference guidelines 2012.
102 Horwich A et al. Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
103 Hovland A et al. Subjective sleep quality in relation to inhibition and heart rate variability in patients with panic disorder.
104 Hu YJ et al. Meta-analysis of gene-level associations for rare variants based on single-variant statistics.
105 Huhta H et al. Ventricular functional responses to altered loading conditions in the fetal heart: a sheep study with acute ascending aorta occlusion.
106 Huhta H et al. Acute ascending aorta occlusion leads to decreased cerebral perfusion pressure in a fetal sheep.
107 Huopio H et al. Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes.
108 Huotari A et al. Effect of surface chemistry of porous silicon microparticles on glucagon-like peptide-1 (GLP-1) loading, release and biological activity.
109 Huyghe JR et al. Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.
110 Hyttinen JMT et al. Maturation of autophagosomes and endosomes: A key role for Rab7.
111 Hyvärinen A et al. Recombination of replicon and helper RNAs and the emergence of propagation-competent vectors upon Sindbis virus vector production.
112 Härkänen M et al. Information received from medication errors - using a web-based error reproting system.
113 Härkänen M et al. Medication errors: what hospital reports reveal about staff views.
114 Härkänen M et al. Terveydenhuollon henkilöstön näkemykset lääkityspoikkeamien estämisestä erikoissairaanhoidossa.
115 Ihaksi E et al. Erikoissairaanhoidon osastonhoitajan perehdyttäminen tasapainotetun tuloskortin osaamisalueisiin.
116 Ihlberg L et al. Early clinical outcome of aortic transcatheter valve-in-valve implantation in the Nordic countries.
117 Iivarinen JT et al. Experimental and computational analysis of soft tissue mechanical response under negative pressure in forearm.
118 Ilves I et al. Outpatient antibiotic use and the incidence of acute appendicitis in Finland: A nationwide study from 1990-2008.
119 Ilves T, Harvima IT. OX40 ligand and OX40 are increased in atopic dermatitis lesions but do not correlate with clinical severity.
120 Immonen R et al. MRI biomarkers for post-traumatic epileptogenesis.
121 Iqbal K et al. Clinical symptoms and symptom signatures of Alzheimer's disease subgroups.
122 Isola J et al. Geeniprofilointitestien merkitys rintasyövän hoidon valinnassa.
123 Jahnukainen K et al. Bone marrow remission status predicts leukemia contamination in ovarian biopsies collected for fertility preservation.
124 Jahnukainen T et al. Prednisone in the treatment of tubulointerstitial nephritis in children.
125 Jalkanen J et al. Tantaalimetallin käyttö acetabulum-revisioissa - 7 vuoden seurannan tulokset.
126 Jalkanen J et al. The impact of posterior urethral valves on adult quality of life.
127 Jantunen E et al. Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT.
128 Janícková H et al. Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid ß(1-42).
129 Jaronen M et al. Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production.
130 Johnson MP et al. Genetic dissection of the pre-eclampsia susceptibility locus on chromosome 2q22 reveals shared novel risk factors for cardiovascular disease.
131 Jokelainen M et al. Mentorship provision for student nurses: Conceptions of Finnish and British mentors in healthcare placements.
132 Jokelainen M et al. Finnish and British mentors' conceptions of facilitating nursing students' placement learning and professional development.
133 Jokelainen M et al. Seamless and committed collaboration as an essential factor in effective mentorship for nursing students: Conceptions of Finnish and British mentors.
134 Jonsdottir SE et al. Adherence to the Nordic Nutrition Recommendations in a Nordic population with metabolic syndrome: high salt consumption and low dietary fibre intake (The SYSDIET study).
135 Joukainen A et al. Lonkkakivun yleiset syyt. Nivelrikko, ahdas lonkka -oireyhtymä ja ison sarvennoisen kipuoireyhtymä.
136 Joukamo L et al. Rasvainen kala muokkaa HDL-hiukkaskokoa ja lipidipitoisuuksia.
137 Juhakoski R et al. Determinants of pain and functioning in hip osteoarthritis - a two-year prospective study.
138 Julkunen P et al. Feasibility of automated analysis and inter-examiner variability of cortical silent period induced by transcranial magnetic stimulation.
139 Julkunen P et al. TMS-EEG reveals impaired intracortical interactions and coherence in Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1).
140 Julkunen P et al. A review of the combination of experimental measurements and fibril-reinforced modeling for investigation of articular cartilage and chondrocyte response to loading.
141 Junno J et al. Fetal sheep left ventricle is more sensitive than right ventricle to progressively worsening hypoxemia and acidemia.
142 Junttila E et al. Neurogenic pulmonary edema in patients with nontraumatic intracerebral hemorrhage: predictors and association with outcome.
143 Juonala M et al. Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring.
144 Justenhoven C et al. The UGT1A6_19_GG genotype is a breast cancer risk factor.
145 Jutila L. Surgical treatment of refractory temporal lobe epilepsy. Predictors of long-term outcome.
146 Juusela P et al. Xerostomia in hereditary gelsolin amyloidosis.
147 Järvelin-Pasanen S et al. Effects of implementing an ergonomic work schedule on heart rate variability in shift-working nurses.
148 Järvelin-Pasanen S et al. Differences in heart rate variability of female nurses between and within normal and extended work shifts.
149 Jääskeläinen A et al. Meal frequencies modify the effect of common genetic variants on body mass index in adolescents of the Northern Finland birth cohort 1986.
150 Jääskeläinen A et al. Associations of meal frequency and breakfast with obesity and metabolic syndrome traits in adolescents of Northern Finland Birth Cohort 1986.
151 Jääskeläinen JE. Role of intraoperative neurophysiological monitoring during fluorescence-guided resection surgery. Aiming at seemingly complete resection of diffuse gliomas under 5-ALA guidance-Is it safe?
152 Jääskeläinen P et al. Two founder mutations in the alpha-tropomyosin and the cardiac myosin-binding protein C genes are common causes of hypertrophic cardiomyopathy in the Finnish population.
153 Jääskeläinen T et al. Genetic predisposition to obesity and lifestyle factors -- the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study.
154 Kaarniranta K. Silmänpohjan kostean ikärappeuman hoito.
155 Kaarniranta K et al. Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration.
156 Kaarteenaho R. Idiopaattisen keuhkofibroosin lääkehoito kehittyy.
157 Kaarteenaho R. The current position of surgical lung biopsy in the diagnosis of idiopathic pulmonary fibrosis.
158 Kaarteenaho R et al., toim. Keuhkosairaudet. Diagnostiikka ja hoito.
159 Kaarteenaho R et al. Keuhkoputkien taudit, bronkiektasiat ja kystinen fibroosi.
160 Kaarteenaho R, Kinnula V. Interstitiaaliset keuhkosairaudet ja niiden erotusdiagnostiikka.
161 Kaarteenaho R, Kinnula V. Idiopaattiset interstitiaaliset pneumoniat.
162 Kaarteenaho R, Kinnula V. Sidekudostauteihin liittyvät keuhkomuutokset.
163 Kahlos K et al. Keuhkovaltimoiden verenpainetauti ja krooninen tromboembolinen keuhkoverenpainetauti. Harvinaiset, mutta tärkeät kohonneen keuhkoverenpaineen aiheuttajat.
164 Kaitainen S et al. TiO2 coating promotes human mesenchymal stem cell proliferation without the loss of their capacity for chondrogenic differentiation.
165 Kaivorinne AL et al. Clinical characteristics of C9ORF72-linked frontotemporal lobar degeneration.
166 Kanerva N et al. Adherence to the Baltic Sea diet consumed in the Nordic countries is associated with lower abdominal obesity.
167 Kangasniemi M et al. Ethical issues in patient safety: Implications for nursing management.
168 Kankkunen P, Vehviläinen-Julkunen K. Tutkimus hoitotieteessä.
169 Karavirta L et al. Heart rate dynamics after combined strength and endurance training in middle-aged women: Heterogeneity of responses.
170 Karesvuo P et al. Alveolar bone loss associated with age-related macular degeneration in males.
171 Karihtala P et al. Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype.
172 Karppinen J et al. Alaselkäpotilaan anamneesi.
173 Karppinen J et al. Alaselkäpotilaan kliininen tutkimus.
174 Karppinen J et al. Alaselkäpotilaan tutkiminen: videot.
175 Karvonen HM et al. Myofibroblast expression in airways and alveoli is affected by smoking and COPD.
176 Karvonen M et al. Elevated head circumference-to-height ratio is an early and frequent feature in children with neurofibromatosis type 1.
177 Kasperaviciute D et al. Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A.
178 Kaukonen KM et al. Heparin-binding protein (HBP) in critically ill patients with influenza A(H1N1) infection.
179 Kaukonen KM et al. Age of red blood cells and outcome in acute kidney injury.
180 Kaunisto J et al. Idiopathic pulmonary fibrosis--a systematic review on methodology for the collection of epidemiological data.
181 Kauppi T et al. Constructing benchmark databases and protocols for medical image analysis: diabetic retinopathy.
182 Kauppinen A et al. Inflammation as a target of minocycline: special interest in the regulation of inflammasome signaling.
183 Kauppinen A et al. Antagonistic crosstalk between NF-kB and SIRT1 in the regulation of inflammation and metabolic disorders.
184 Keikkala E et al. First trimester hyperglycosylated human chorionic gonadotrophin in serum - A marker of early-onset preeclampsia.
185 Kemppainen V et al. Nurses' roles in health promotion practice: an integrative review.
186 Kero M et al. Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population.
187 Kerola AM et al. Cardiovascular comorbidities antedating the diagnosis of rheumatoid arthritis.
188 Kervinen K et al. Clinical outcome after crush versus culotte stenting of coronary artery bifurcation lesions . The Nordic stent technique study 36-month follow-up results.
189 Keränen P et al. Parkinson´s disease patients in institutionalized care.
190 Keränen T et al. Uusimmat epilepsialääkkeet.
191 Keränen T, Liikkanen S. Medication reminder service for mobile phones: an open feasibility study in patients with Parkinson´s disease.
192 Keski-Nisula L et al. Maternal intrapartum antibiotics and decreased vertical transmission of Lactobacillus to neonates during birth.
193 Keskinen E et al. Interaction between parental psychosis and risk factors during pregnancy and birth for schizophrenia - The Northern Finland 1966 Birth Cohort study.
194 Kiiski H et al. Healthy human CSF promotes glial differentiation of hESC-derived neural cells while retaining spontaneous activity in existing neuronal networks.
195 Kinnunen K et al. LDLR-/-ApoB100/100 mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina.
196 Kiviniemi M et al. Antipsychotics and mortality in first-onset schizophrenia: prospective Finnish register study with 5-year follow-up.
197 Kivipelto M et al. The Finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): study design and progress.
198 Klettner A et al. Cellular and molecular mechanisms of age-related macular degeneration: From impaired autophagy to neovascularization.
199 Kobrina Y et al. Cluster analysis of infrared spectra can differentiate intact and repaired articular cartilage.
200 Kohen Avramoglu R et al. The genetic and metabolic determinants of cardiovascular complications in type 2 diabetes: recent insights from animal models and clinical investigations.
201 Koivisto AM et al. Poor cognitive outcome in shunt-responsive idiopathic normal pressure hydrocephalus.
202 Koivu A. Clinical supervision and well-being at work. A four-year follow-up study on female hospital nurses.
203 Kokki M et al. The influence of timing on the effectiveness of epidural blood patches in parturients.
204 Kokko S. Terveyskeskukset.
205 Kokko S. Terveyspalveluiden järjestämisen perusratkaisut.
206 Kokkonen J et al. Fallot´n tetralogia.
207 Korhonen RK et al. Computational models of articular cartilage.
208 Korhonen U et al. Assessment of bony pelvis and vaginally assisted deliveries.
209 Korkeila J et al. Motivations for entering psychiatry: a survey of Finnish psychiatrists and residents.
210 Korkiamäki P et al. Prevalence of the primary LHON mutations in Northern Finland associated with bilateral optic atrophy and tobacco-alcohol amblyopia.
211 Koskela HO, Purokivi MK. Capability of hypertonic saline cough provocation test to predict the response to inhaled corticosteroids in chronic cough: a prospective, open-label study.
212 Koskela HO, Purokivi MK. Airway oxidative stress in chronic cough.
213 Koskela HO et al. Hyperglycaemia during exacerbations of asthma and chronic obstructive pulmonary disease.
214 Koski AM et al. The effectiveness of teriparatide in the clinical practice--attenuation of the bone mineral density outcome by increasing age and bisphosphonate pretreatment.
215 Koskinen SK et al. CT arthrography of the wrist using a novel, mobile, dedicated extremity cone-beam CT (CBCT.
216 Kovalainen M et al. Development of porous silicon nanocarriers for parenteral Peptide delivery.
217 Kozakova M et al. Insulin sensitivity and carotid intima-media thickness: relationship between insulin sensitivity and cardiovascular risk study.
218 Kröger H. FRAX-murtumariskilaskuri osteoporoosin diagnostiikassa ja hoidossa.
219 Kröger L et al. Osteochondral lesions in children with juvenile idiopathic arthritis.
220 Krüger AJ et al. Pre-hospital critical care by anaesthesiologist-staffed pre-hospital services in Scandinavia: a prospective population-based study.
221 Krüger L et al. Health-related quality of life and socioeconomic situation among diastrophic dysplasia patients in Finland.
222 Kuhlman I. Accountability in couple therapy for depression. A mixed methods study in a naturalistic setting in Finland.
223 Kuhlman I et al. The therapeutic alliance in couple therapy for depression: predicting therapy progress and outcome from assessments of the alliance by the patient, the spouse, and the therapists.
224 Kuhlman I et al. Couple therapy for depression within a naturalistic setting in Finland: Factors related to change of the patient and the spouse.
225 Kuiri-Hänninen T et al. Transient postnatal secretion of androgen hormones is associated with acne and sebaceous gland hypertrophy in early infancy.
226 Kuiri-Hänninen T et al. Postnatal ovarian activation has effects in estrogen target tissues in infant girls.
227 Kujala UM et al. Long-term leisure-time physical activity and serum metabolome.
228 Kukkonen J et al. Operatively treated traumatic versus non-traumatic rotator cuff ruptures: a registry study.
229 Kukkonen J et al. The effect of glenohumeral osteoarthritis on the outcome of isolated operatively treated supraspinatus tears.
230 Kukkonen J et al. The effect of waiting time on operatively treated non-traumatic rotator cuff tears.
231 Kukkonen J et al. Investigating minimal clinically important difference for Constant score in patients undergoing rotator cuff surgery.
232 Kulkas A et al. Novel parameters reflect changes in morphology of respiratory events during weight loss.
233 Kulkas A et al. Novel parameters for evaluating severity of sleep disordered breathing and for supporting diagnosis of sleep apnea-hypopnea syndrome.
234 Kulkas A et al. Novel parameters indicate significant differences in severity of obstructive sleep apnea with patients having similar apnea-hypopnea index.
235 Kulmala KAM et al. Diffusion of ionic and non-ionic contrast agents in articular cartilage with increased cross-linking--Contribution of steric and electrostatic effects.
236 Kuoppa P et al. Dynamic modeling of respiratory sinus arrhythmia component from HRV with multivariate Kalman smoother.
237 Kuosmanen A et al. Patient safety culture in two Finnish state-run forensic psychiatric hospitals.
238 Kuusisto J, Laakso M. Update on type 2 diabetes as a cardiovascular disease risk equivalent.
239 Kvist T et al. How magnetic are Finnish hospitals measured by transformational leadership and empirical quality outcomes?
240 Kvist T et al. Does Finnish hospital staff job satisfaction vary across occupational groups?
241 Kytövuori L et al. WFS1 variants in Finnish patients with diabetes mellitus, sensorineural hearing impairment or optic atrophy, and in suicide victims.
242 Käkelä P et al. Mahalaukun ohitus lihavuusleikkauksena: yhden keskuksen kymmenen vuoden kokemukset ja seurannan haasteet.
243 Kämäläinen A et al. GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer´s disease patients.
244 Kärkkäinen H. The ambulatory arterial stiffness index and carotid stiffness in pregnancy.
245 Kärkkäinen H et al. Need for insulin to control gestational diabetes is reflected in the ambulatory arterial stiffness index.
246 Kärkkäinen O et al. AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study.
247 Kärkkäinen OK et al. Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics.
248 Kääriäinen T et al. Lumbar paraspinal and biceps brachii muscle function and movement perception in lumbar spinal stenosis.
249 Laine CM et al. WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta.
250 Lambert J-C et al. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer´s disease.
251 Lambert JC et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
252 Lamminpää R et al. Smoking among older childbearing women - a marker of risky health behaviour a registry-based study in Finland .
253 Laplante MA et al. Distinct metabolic and vascular effects of dietary triglycerides and cholesterol in atherosclerotic and diabetic mouse models.
254 Lappi-Blanco E et al. Divergence of tight and adherens junction factors in alveolar epithelium in pulmonary fibrosis.
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380 Rantalaiho VM et al. Decline in work disability caused by early rheumatoid arthritis: results from a nationwide Finnish register, 2000-8.
381 Rantamäki T et al. The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease.
382 Rauma PH et al. The relationship between self-reported and registry-based data on use of psychoactive medications in postmenopausal women.
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385 Rautio N et al. Financial satisfaction and its relationship to depressive symptoms in middle-aged and older adults: Results from the FIN-D2D survey.
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405 Ryynänen O-P et al. Bayesian predictors of very poor health related quality of life and mortality in patients with COPD.
406 Ryynänen OP et al. Efficacy of a multicomponent support programme for the caregivers of disabled persons . A randomised controlled study.
407 Räisänen S et al. The burden of OASIS increases along with socioeconomic position - register-based analysis of 980,733 births in Finland.
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409 Räisänen S et al. True umbilical cord knot and obstetric outcome.
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414 Räisänen S et al. Fear of childbirth predicts postpartum depression: a population-based analysis of 511 422 singleton births in Finland.
415 Räisänen S et al. Socioeconomic status affects the prevalence, but not the perinatal outcomes, of in vitro fertilization pregnancies.
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504 Tuomainen PO et al. Five-year clinical outcome of titanium-nitride-oxide-coated bioactive stents versus paclitaxel-eluting stents in patients with acute myocardial infarction: long-term follow-up from the TITAX AMI trial.
505 Tuomilehto H et al. Obesity and obstructive sleep apnea - clinical significance of weight loss.
506 Tuomilehto H et al. Weight reduction and increased physical activity to prevent the progression of obstructive sleep apnea: a 4-year observational postintervention follow-up of a randomized clinical trial .
507 Tuppurainen L et al. Functional MRI measurements to predict early adenoviral gene therapy response in ovarian cancer mouse model.
508 Tuppurainen L et al. Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer.
509 Turkki P et al. Cell susceptibility to baculovirus transduction and echovirus infection is modified by protein kinase C phosphorylation and vimentin organization.
510 Turpeinen A, Saraste A. Äkilliset sydänläppien toimintahäiriöt ja sydämen rakennevauriot.
511 Turpeinen AM et al. Antihypertensive effects of bioactive tripeptides - a random effects meta-analysis.
512 Turunen AW et al. Fish consumption, omega-3 fatty acids, and environmental contaminants in relation to low-grade inflammation and early atherosclerosis.
513 Turunen H et al. Patient safety culture in acute care: A web-based survey of nurse managers' and registered nurses' views in four Finnish hospitals.
514 Turunen MJ et al. Composition and microarchitecture of human trabecular bone change with age and differ between anatomical locations.
515 Turunen MP et al. Epigenetic regulation in vascular cells.
516 Tähtinen OI et al. Stent-assisted embolization of recurrent or residual intracranial aneurysms.
517 Uosukainen H et al. Kyselytutkimus opioidikorvaushoidon totettamisesta suomalaisissa avoapteekeissa.
518 Uosukainen H et al. First insights into community pharmacy based buprenorphine-naloxone dispensing in Finland.
519 Uosukainen H et al. The effect of an electronic medicine dispenser on diversion of buprenorphine-naloxone-experience from a medium-sized Finnish city.
520 Utriainen P et al. Blood erythrocyte and hemoglobin concentrations in premature adrenarche.
521 Uusitupa M et al. Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome - a randomized study (SYSDIET).
522 Uusitupa M et al. Kohti terveellistä pohjoismaista ruokavaliota.
523 Uusitupa M, Schwab U. Diet, inflammation and prediabetes - impact of quality of diet.
524 Vaahersalo J et al. Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units. the FINNRESUSCI study.
525 Vaajoki A et al. Music intervention study in abdominal surgery patients: Challenges of an intervention study in clinical practice.
526 Vaalto S et al. Long-term plasticity may be manifested as reduction or expansion of cortical representations of actively used muscles in motor skill specialists.
527 Vainiomäki P et al. Ohjauksessa osaamista, oivallusta ja onnistumisen iloa. Opas yleislääketieteen erikoistumiseen.
528 Vaismoradi M et al. A qualitative study on Iranian nurses' experiences and perspectives on how to provide safe care in clinical practice.
529 Vaismoradi M et al. Content analysis and thematic analysis: Implications for conducting a qualitative descriptive study.
530 Vaittinen M et al. Downregualtion of CPPED1 expression improves glucose metabolism in vitro in adipocytes.
531 Van Poppel H et al. Penile cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
532 Vanamo K. Sikiökirurgia.
533 Varmavuo V. Plerixafor in autologous stem cell transplantation.
534 Varmavuo V et al. CD34+ cell subclasses and lymphocyte subsets in blood grafts collected after various mobilization methods in myeloma patients.
535 Vehviläinen-Julkunen K. Sairaalat tarvitsevat oman CV:n.
536 Veijalainen A et al. Metabolic risk factors are associated with stiffness index, reflection index and finger skin temperature in children - Physical activity and nutrition in children (PANIC) study.
537 Velayudhan L et al. Entorhinal cortex thickness predicts cognitive decline in Alzheimer´s disease.
538 Venesmaa S et al. Imaging and treatment features of idiopathic pancreatitis and pancreas divisum in a young man: A case report.
539 Vepsäläinen S et al. Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer´s disease.
540 Vermeiren APA et al. The association between APOE e4 and Alzheimer-type dementia among memory clinic patients is confined to those with a higher education. The DESCRIPA Study.
541 Viiri J et al. Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells.
542 Vimaleswaran KS et al. Causal relationship between obesity and vitamin D status: Bi-directional Mendelian randomization analysis of multiple cohorts.
543 Viswanathan J et al. Ubiquilin-1 modulates y-secretase-mediated e-site cleavage in neuronal cells.
544 Vos SJB et al. Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI.
545 Vottonen P et al. Changes in neurophysiologic markers of visual processing following beneficial anti-VEGF treatment in macular degeneration.
546 Voutilainen A et al. Itsejärjestyvä piirrekartta SOM: joustava tilastomenetelmä Likert-asteikollisten kyselylomakeaineistojen ryhmittelyyn.
547 Vuorinen M et al. Changes in vascular factors 28 years from midlife and late-life cortical thickness.
548 Väänänen SP et al. Repeatability of digital image correlation for measurement of surface strains in composite long bones.
549 Wahlin KJ et al. Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death.
550 Westphal M et al. Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial.
551 Willer CJ et al. Discovery and refinement of loci associated with lipid levels.
552 Wirth T et al. History of gene therapy.
553 Wu Y et al. Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.
554 Xie W et al. Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.
555 Yaghootkar H et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes .
556 Yli-Kyyny T et al. Perioperative complications after cemented or uncemented hemiarthroplasty in hip fracture patients.
557 Yli-Ollila H et al. Axial and radial waveforms in common carotid artery: an advanced method for studying arterial elastic properties in ultrasound imaging.
558 Ylitörmänen T et al. Sairaanhoitajien yhteistyö sairaalassa - kyselytutkimus.
559 Ylä-Herttuala S. Cardiovascular gene therapy with vascular endothelial growth factors.
560 Ylönen S et al. Variations of mitochondrial DNA polymerase gamma in patients with Parkinson's disease.
561 Zaproudina N et al. Are the infrared thermography findings skin temperature-dependent? a study on neck pain patients.
562 Zaproudina N et al. Nitroglycerin-induced changes in facial skin temperature: 'cold nose' as a predictor of headache?
563 Zilberter M et al. Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer´s disease.
Kuopion yliopistollinen sairaala Kuopio University Hospital
Julkaisutietokanta 12.1.2018 Publications Data Base 12.1.2018