Kliinisen farmakologian yks.

Julkaisut 2004
Publications 2004

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1 Anichtchik OV et al. Neurochemical and behavioural changes in zebrafish Danio rerio after systemic administration of 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
2 Antila S et al. Pharmacokinetics of levosimendan and its active metabolite OR-1896 in rapid and slow acetylators.
3 Bergström M et al. Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant.
4 Cayla C et al. Cloning, characterisation and identification of several polymorphisms in the promoter region of the human alpha2B-adrenergic receptor gene.
5 Fagerholm V et al. Altered glucose homeostasis in alpha2A-adrenoceptor knockout mice.
6 Fagerholm V et al. [Ethyl-3H]-79948-197 alpha2-adrenoceptor autoradiography validation in alpha2-adrenoceptor knockout mice.
7 Flordellis C et al. Clinical and pharmacological significance of alpha2-adrenoceptor polymorphisms in cardiovascular diseases.
8 Ge H. Regulation of Intracellular Calcium by alpha2-Adrenoceptors.
9 Hagelberg N et al. Alfentanil increases cortical dopamine D2/D3 receptor binding in healthy subjects.
10 Holopainen IE et al. Mechanisms of kainate-induced region-specific neuronal death in immature organotypic hippocampal slice cultures.
11 Huupponen R et al. Pharmacokinetics of deramciclane and N-desmethylderamciclane after single and repeated oral doses in healthy volunteers.
12 Ingman K et al. Comparison of deramciclane to benzodiazepine agonists in behavioural activity of mice and in alcohol drinking of alcohol-preferring rats.
13 Kailajärvi MEH et al. Serum bone markers in breast cancer patients during 5-fluorouracil, epirubicin and cyclophosphamide (FEC) therapy.
14 Laine K. Lääkepitoisuudet - mitä tutkin ja milloin.
15 Laine K. Kliinisesti tärkeät lääkkeiden yhteisvaikutukset.
16 Laine K et al. Effect of the novel anxiolytic drug deramciclane on cytochrome P450 2D6 activity as measured by desipramine pharmacokinetics.
17 Laine K et al. Severe adverse effects in an newborn with two defective CYP2D6 alleles after exposure to paroxetine during late pregnancy.
18 Lopez-Picon F et al. Resistance of neurofilaments to degradation, and lack of neuronal death and mossy fiber sprouting after kainic acid-induced status epilepticus in the developing rat hippocampus.
19 Lähdesmäki J. Disturbed Brain Noradrenergic Balance and Increased Neurobehavioural Sensitivity of alpha2A-Adrenoceptor Knockout Mice.
20 Lähdesmäki J et al. Alpha2A-adrenoceptors are important modulators of the effects of D-amphetamine on startle reactivity and brain monoamines.
21 Långsjö JW et al. Effects of subanesthetic ketamine on regional cerebral glucose metabolism in humans.
22 Mansikka H et al. Alpha2A Adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia.
23 Martikainen IK et al. Kainate down-regulates a subset of GABAA receptor subunits expressed in cultured mouse cerebellar granule cells.
24 Mäntyranta R et al. Lääkehoidon kehittämiskeskus - ROHTO lääkärin tukena.
25 Olli-Lähdesmäki T et al. Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation.
26 Penttilä J et al. Cardiovascular and parasympathetic effects of dexmedetomidine in healthy subjects.
27 Penttilä J et al. Effects of atipamezole - a selective alfa2-adrenoceptor antagonist - on cardiac parasympathetic regulation in human subjects.
28 Ruuskanen JO et al. Identification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafish.
29 Savontaus E et al. Metabolic effects of transgenic melanocyte-stimulating hormone overexpression in lean and obese mice.
30 Tirkkonen T, Laine K. Drug interactions with the potential to prevent prodrug activation as a common source of irrational prescribing in hospital inpatients.
31 Özdogan Ü et al. The involvement of alpha2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice.
32 Özdogan ÜK et al. Loss of amitriptyline analgesia in alpha2A-adrenoceptor deficient mice.
Julkaisutietokanta 26.10.2005 Publications Data Base 26.10.2005