Neurologian yksikkö
Department of Neurology

Julkaisut 2020
Publications 2020

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1 Akenine U, Barbera M, Beishuizen CRl, Fallah Pour M, Guillemont J, Rosenberg A, Coley N, Mangialasche F, Salo L, Savy S, Pols AJ, Andrieu S, Richard E, Soininen H, Moll van Charante E, Kivipelto M. Attitudes of at-risk older adults about prevention of cardiovascular disease and dementia using eHealth: a qualitative study in a European context. BMJ Open 2020:10(8):e037050.
2 Arzimanoglou A, Brandl U, Cross JH, Gil-Nagel A, Lagae L, Johannessen Landmark C, Specchio N, Nabbout R, Thiele EA, Gubbay O, ..., Kälviäinen R, et al. Epilepsy and cannabidiol: a guide to treatment. Epileptic Disord 2020:22(1):1-14.
3 Barbera M, Kulmala J, Lisko I, Pietilä E, Rosenberg A, Hallikainen I, Hallikainen M, Laatikainen T, Lehtisalo J, Neuvonen E, Rusanen M, Soininen H, Tuomilehto J, Ngandu T, Solomon A, Kivipelto M. Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol. BMC Geriatr 2020:20(1):238.
4 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, ..., Soininen H, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry 2020:25(8):1859-1875.
5 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, et al, Soininen. Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry 2020:25(8):1901-1903.
6 Coley N, Hoevenaar-Blom MP, van Dalen J, Moll van Charante EP, Kivipelto M, Soininen H, Andrieu S, Richard E. Dementia risk scores as surrogate outcomes for lifestyle-based multidomain prevention trials-rationale, preliminary evidence and challenges. Alzheimers Dement 2020:16(12):1674-1685.
7 Deckers K, Barbera M, Köhler S, Ngandu T, van Boxtel M, Rusanen M, Laatikainen T, Verhey F, Soininen H, Kivipelto M, Solomon A. Long-term dementia risk prediction by the LIBRA score: A 30-year follow-up of the CAIDE study. Int J Geriatr Psychiatry 2020:35(2):195-203.
8 Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG, Cervenka S, Conzelmann A, ..., Soininen Hilkka, et al. The genetic architecture of human brainstem structures and their involvement in common brain disorders. Nat Commun 2020:11(1):4016.
9 George A, Kuzniecky R, Rusinek H, Pardoe HR, ..., Kälviäinen R, et al. Standardized Brain MRI Acquisition Protocols Improve Statistical Power in Multicenter Quantitative Morphometry Studies. J Neuroimaging 2020:30 (1):127-133.
10 Haapanen M, Katisko K, Hänninen T, Krüger J, Hartikainen P, Haapasalo A, Remes AM, Solje E. C9orf72 Repeat Expansion Does Not Affect the Phenotype in Primary Progressive Aphasia. J Alzheimer Dis 2020:78(3):919-925.
11 Hoffmann D, Huber N, Leskelä S, Rostalski H, Solje E, Remes AM, Haapasalo A. Frontotemporal dementia: a conference report from the 2nd FinFTD Symposium. Neurodegenerat Dis Manage 2020:10(3):119-123.
12 Hänninen K, Jääskeläinen O, Herukka S, Soilu-Hänninen M. Vitamin D supplementation and serum neurofilament light chain in interferon-beta-1b-treated MS patients. Brain Behav 2020:10(9):e01772.
13 Jääskeläinen O, Hall A, Tiainen M, van Gils M, Lötjönen J, Kangas AJ, Helisalmi S, Pikkarainen M, Hallikainen M, Koivisto A, Hartikainen P, Hiltunen M, Ala-Korpela M, Soininen P, Soininen H, Herukka S. Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease. J Alzheimer Dis 2020:74(1):277-286.
14 Kaarniranta K, Uusitalo H, Blasiak J, Felszeghy S, Kannan R, Kauppinen A, Salminen A, Sinha D, Ferrington D. Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration. Prog Retin Eye Res 2020:79:100858.
15 Kaipainen A, Jääskeläinen O, Liu Y, Haapalinna F, Nykänen N, Vanninen R, Koivisto AM, Julkunen V, Remes AM, Herukka S. Cerebrospinal Fluid and MRI Biomarkers in Neurodegenerative Diseases: A Retrospective Memory Clinic-Based Study. J Alzheimer Dis 2020:75(3):751-765.
16 Katisko K, Cajanus A, Jääskeläinen O, Kontkanen A, Hartikainen P, Korhonen VE, Helisalmi S, Haapasalo A, Koivumaa-Honkanen H, Herukka S, Remes AM, Solje E. Serum neurofilament light chain is a discriminative biomarker between frontotemporal lobar degeneration and primary psychiatric disorders. J Neurol 2020:267(1):162-167.
17 Katisko K, Solje E, Korhonen P, Jääskeläinen O, Loppi S, Hartikainen P, Koivisto AM, Kontkanen A, Korhonen VE, Helisalmi S, Malm T, Herukka S, Remes AM, Haapasalo A. Peripheral inflammatory markers and clinical correlations in patients with frontotemporal lobar degeneration with and without the C9orf72 repeat expansion. J Neurol 2020:267(1):76-86.
18 Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, ..., Soininen H, et al. Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nat Neurosci 2020:23(2):295.
19 Kurbatova N, Garg M, Whiley L, Chekmeneva E, Jiménez B, Gómez-Romero M, Pearce J, Kimhofer T, D'Hondt E, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Aarsland D, Nevado-Holgado A, Liu B, Snowden S, Proitsi P, Ashton NJ, et al. Urinary metabolic phenotyping for Alzheimer's disease. Sci Rep 2020:10(1):21745.
20 Kälviäinen R. Etävastaanottoihin vauhtia koronakeväänä. Epilepsia-lehti 2020:51(4):6-7.
21 Kälviäinen R. Epilepsian digihoitopolku auttaa saamaan yhteyden hoitopaikkaan silloin kun on tarve. Epilepsia-lehti 2020:51(4):4-5.
22 Kälviäinen R, et al, Vaikean epilepsian kansallinen koordinaatiotyöryhmä. Harvinaisepilepsiat - mistä on kyse? Epilepsia-lehti 2020:51(5):8-11.
23 Lamberink HJ, Otte WM, Blümcke I, Braun KPJ, ..., Kälviäinen R, et al. Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study. Lancet Neurol 2020:19(9):748-757.
24 Larivière S, Rodríguez-Cruces R, Royer J, Caligiuri ME, Gambardella A, Concha L, Keller SS, Cendes F, Yasuda C, Bonilha L, Gleichgerrcht E, Focke NK, Domin M, von Podewills F, Langner S, Rummel C, Wiest R, Martin P, ..., Kälviäinen R, et al. Network-based atrophy modeling in the common epilepsies: A worldwide ENIGMA study. Sci Adv 2020:6(47):eabc6457.
25 Lehesjoki A-E, Kälviäinen R. Progressive Myoclonic Epilepsy Type 1. In: Adam MP, Ardinger HH, Pagon RA, et al, eds. GeneReviews [Internet]. https://www.ncbi.nlm.nih.gov/books/. Seattle (WA), USA: University of Washington, 2020.
26 Leino A, Westeren-Punnonen S, Töyräs J, Myllymaa S, Leppänen T, Ylä-Herttuala S, Muraja-Murro A, Kantanen A, Autere J, Jäkälä P, Mervaala E, Myllymaa K. Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea. Sleep Breath 2020:24(4):1495-1505.
27 Liang Y, Ngandu T, Laatikainen T, Soininen H, Tuomilehto J, Kivipelto M, Qiu C. Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland. PLoS Medicine 2020:17(12):e1003474.
28 Mars N, Widén E, Kerminen S, Meretoja T, Pirinen M, della Briotta Parolo P, Palta P, ..., Pulkki K, Mannermaa A, Kosma VM, Remes A, Soininen H, Harvima I, Pihlajamäki J, Kaarniranta K, Laakso M, Kälviäinen R, et al. The role of polygenic risk and susceptibility genes in breast cancer over the course of life. Nat Commun 2020:11(1):6383.
29 Marttinen M, Ferreira CB, Paldanius KM, Takalo M, Natunen T, Mäkinen P, Leppänen L, Leinonen V, Tanigaki K, Kang G, Hiroi N, Soininen H, Rilla K, Haapasalo A, Hiltunen M. Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of A[beeta]. Cells 2020:9(11):2482.
30 Muurling M, Rhodius-Meester HF, Pärkkä J, van Gils M, Frederiksen KS, Bruun M, Hasselbalch SG, Soininen H, Herukka S, Hallikainen M, Teunissen CE, Jelle Visser P, Scheltens P, van der Flier WM, Mattila J, Lötjönen J, de Boer C. Gait Disturbances are Associated with Increased Cognitive Impairment and Cerebrospinal Fluid Tau Levels in a Memory Clinic Cohort. J Alzheimer Dis 2020:76(3):1061-1070.
31 Mårtensson G, Ferreira D, Granberg T, Cavallin L, Oppedal K, Padovani A, Rektorova I, Bonanni L, Pardini M, Kramberger MG, Taylor J, Hort J, Snædal J, Kulisevsky J, Blanc F, Antonini A, Mecocci P, Vellas B, ..., Soininen Hilkka, et al. The reliability of a deep learning model in clinical out-of-distribution MRI data: A multicohort study. Med Image Anal 2020:66:101714.
32 Niestroj L-M, Perez-Palma E, Howrigan DP, Zhou Y, Cheng F, Saarentaus E, Nürnberg P, Stevelink R, Daly MJ, Palotie A, Lal D, ..., Kälviäinen R, et al. Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17458 subjects. Brain 2020:143(7):2106-2118.
33 Nikolaev A, Higby E, Hyun J, Lehtonen M, Ashaie S, Hallikainen M, Hänninen T, Soininen H. Production of Inflected Novel Words in Older Adults With and Without Dementia. Cogn Sci 2020:44(8):e12879.
34 Onatsu J, Vanninen R, Jäkälä P, Mustonen P, Pulkki K, Korhonen M, Hedman M, Höglund K, Blennow K, Zetterberg H, Herukka S, Taina M. Tau, S100B and NSE as Blood Biomarkers in Acute Cerebrovascular Events. In Vivo 2020:34(5):2577-2586.
35 Pappinen J, Miettinen T, Laukkanen-Nevala P, Jäkälä P, Kantanen A, Mäntyselkä P, Kurola J. The selection of an optimal transportation strategy in urgent stroke missions: a simulation study. Scand J Trauma Resusc Emerg Med 2020:28(1):48.
36 Parviainen L, Kälviäinen R, Jutila L. Impact of diagnostic delay on seizure outcome in newly diagnosed focal epilepsy. Epilepsia Open 2020:5(4):605-610.
37 Pekkala T, Hall A, Mangialasche F, Kemppainen N, Mecocci P, Ngandu T, Rinne JO, Soininen H, Tuomilehto J, Kivipelto M, Solomon A. Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus with Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia. J Alzheimer Dis 2020:76(4):1243-1248.
38 Pekkala T, Hall A, Ngandu T, van Gils M, Helisalmi S, Hänninen T, Kemppainen N, Liu Y, Lötjönen J, Paajanen T, Rinne JO, Soininen H, Kivipelto M, Solomon A. Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline. Front Aging Neurosci 2020:12:228.
39 Pellinen J, Tafuro E, Yang A, Price D, Friedman D, Holmes M, Barnard S, Detyniecki K, Hedge M, Hixson J, Haut S, Kälviäinen R, French J. Focal nonmotor versus motor seizures: The impact on diagnostic delay in focal epilepsy. Epilepsia (NY) 2020:61(12):2643-2652.
40 Raatikainen M, Kälviäinen R, Jutila L, Äikiä M. Cognitive functioning in new-onset juvenile myoclonic epilepsy. Epilepsy Behav 2020:106:107015.
41 Rhodius-Meester HF, Paajanen T, Koikkalainen J, Mahdiani S, Bruun M, Baroni M, Lemstra AW, Scheltens P, Herukka S, Pikkarainen M, Hall A, Hänninen T, Ngandu T, Kivipelto M, van Gils M, Hasselbalch SG, Mecocci P, Remes A, Soininen H, et al. cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders. Alzheimers Dement (Amst) 2020:12(1):e12083.
42 Rosenberg A, Coley N, Soulier A, Kulmala J, Soininen H, Andrieu S, Kivipelto M, Barbera M, et al. Experiences of dementia and attitude towards prevention: a qualitative study among older adults participating in a prevention trial. BMC Geriatr 2020:20(1):99.
43 Rosenow F, Brandt C, Bozorg A, Dimova S, Steiniger-Brach B, Zhang Y, Ferrò B, Holmes GL, Kälviäinen R. Lacosamide in patients with epilepsy of cerebrovascular etiology. Acta Neurol Scand 2020:141(6):473-482.
44 Roubroeks JA, Smith AR, Smith RG, Pishva E, Ibrahim Z, Sattlecker M, Hannon EJ, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Wahlund L, Aarsland D, Proitsi P, Hodges A, Lovestone S, Newhouse SJ, Dobson RJ, et al. An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene. Neurobiol Aging 2020:95:26-45.
45 Saari TT, Hallikainen I, Hintsa T, Koivisto AM. Network structures and temporal stability of self- and informant-rated affective symptoms in Alzheimer's disease. J Affect Disord 2020:276:1084-1092.
46 Sairanen JJ, Kantanen A, Hyppölä HT, Kälviäinen RK. Outcome of status epilepticus and the predictive value of the EMSE and STESS scores: A prospective study. Seizure 2020:75:115-120.
47 Salminen A, Kaarniranta K, Kauppinen A. Exosomal vesicles enhance immunosuppression in chronic inflammation: Impact in cellular senescence and the aging process. Cell Signal 2020:75:109771.
48 Sipilä JOT, Hyppönen J, Kytö V, Kälviäinen R. Unverricht-Lundborg disease (EPM1) in Finland: A nationwide population-based study. Neurology 2020:95(23):e3117-e3123.
49 Sisodiya SM, Whelan CD, Hatton SN, Huynh K, Altmann A, Ryten M, Vezzani A, Caligiuri ME, Labate A, Gambardella A, ..., Kälviäinen R, et al. The Enigma-Epilepsy working group: Mapping diase from large data sets. Human Brain Mapping 2020:43(1):113-128.
50 Stephen R, Solomon A, Ngandu T, Levälahti E, Rinne JO, Kemppainen N, Parkkola R, Antikainen R, Strandberg T, Kivipelto M, Soininen H, Liu Y. White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial. J Alzheimer Dis 2020:78(1):75-86.
51 Takalo M, Wittrahm R, Wefers B, Parhizkar S, Jokivarsi K, Kuulasmaa T, Mäkinen P, Martiskainen H, Wurst W, Xiang X, Marttinen M, Poutiainen P, Haapasalo A, Hiltunen M, Haass C. The Alzheimer's disease-associated protective Plc?2-P522R variant promotes immune functions. Mol Neurodegener 2020:15(1):52.
52 van Wanrooij LL, Hoevenaar-Blom MP, Coley N, Ngandu T, Meiller Y, Guillemont J, Rosenberg A, Beishuizen CR, Moll van Charante EP, Soininen H, Brayne C, Andrieu S, Kivipelto M, Richard E. Pooling individual participant data from randomized controlled trials: Exploring potential loss of information. PLoS ONE 2020:15(5):e0232970.
53 Välimäki T, Gilmartin-Thomas JF, Bell JS, Selander T, Koivisto AM. Longitudinal study of medication use in caregivers of people with Alzheimer's disease - Kuopio ALSOVA study. Dementia (London) 2020:19(5):1573-1585.
54 Väätäinen S, Soini E, Peltola J, Charokopou M, Taiha M, Kälviäinen R. Economic Value of Adjunctive Brivaracetam Treatment Strategy for Focal Onset Seizures in Finland. Adv Ther 2020:37(1):477-500.

Neurologian yksikkö Department of Neurology
Julkaisutietokanta 19.8.2022 Publications Data Base 19.8.2022