Kliininen kemia
Clinical Chemistry

Julkaisut 2013
Publications 2013

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1 Aatola H et al. Simplified definitions of elevated pediatric blood pressure and high adult arterial stiffness.
2 Aho AJ et al. Can electromyographic arousal be detected visually on the Datex-Ohmeda S/5™ anesthesia monitor?
3 Ahtiainen K et al. Autologous adipose stem cells and polylactide discs in the replacement of the rabbit temporomandibular joint disc.
4 Aidar M et al. Effect of genetic polymorphisms in CA6 gene on the expression and catalytic activity of human salivary carbonic anhydrase VI.
5 Alarmo EL et al. Bone morphogenetic protein 4 expression in multiple normal and tumor tissues reveals its importance beyond development.
6 Ampuja M et al. BMP4 inhibits the proliferation of breast cancer cells and induces an MMP-dependent migratory phenotype in MDA-MB-231 cells in 3D environment.
7 Andre K et al. TPH1 A218C polymorphism and temperament in major depression.
8 Anttila V et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine.
9 Armin AL Olama a et al. A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.
10 Aspatwar A et al. Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish.
11 Aspatwar A et al. An update on carbonic anhydrase-related proteins VIII, X and XI.
12 Augello MA et al. Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes.
13 Barbieri CE et al. The mutational landscape of prostate cancer.
14 Berndt SI et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
15 Bruchmann A et al. Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis.
16 Bugiardini R et al. Coronary revascularisation in stable patients after an acute coronary syndrome: a propensity analysis of early invasive versus conservative management in a register-based cohort study.
17 Cheng CY et al. Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error.
18 Cousminer DL et al. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
19 Deloukas P et al. Large-scale association analysis identifies new risk loci for coronary artery disease.
20 Den HOED M et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
21 Do R et al. Common variants associated with plasma triglycerides and risk for coronary artery disease.
22 Eeles R et al. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
23 Elias-Sonnenschein LS et al. Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.
24 Güzel-Akdemir O et al. A class of sulfonamides with strong inhibitory action against the a-carbonic anhydrase from trypanosoma cruzi .
25 Haapasalo T et al. Peroxiredoxins and their expression in ependymomas.
26 Haddad BR et al. STAT5A/B gene locus undergoes amplification during human prostate cancer progression.
27 Hakulinen C et al. Serotonin receptor 1B genotype and hostility, anger and aggressive behavior through the lifespan: the Young Finns study.
28 Haldrup C et al. DNA Methylation Signatures for Prediction of Biochemical Recurrence After Radical Prostatectomy of Clinically Localized Prostate Cancer .
29 Harju AK et al. Carbonic anhydrase III: a neglected isozyme is stepping into the limelight.
30 Heinonen I et al. Sedentary behaviours and obesity in adults: the Cardiovascular Risk in Young Finns Study.
31 Horikoshi M et al. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
32 Hruby A et al. Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies.
33 Häkkinen M et al. Analysis of free, mono- and diacetylated polyamines from human urine by LC-MS/MS.
34 Hällfors J et al. Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study.
35 Illi A et al. No support for a role for BDNF gene polymorphisms rs11030101 and rs61888800 in major depressive disorder or antidepressant response in patients of Finnish origin.
36 Juonala M et al. Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring.
37 Jänis MT et al. Beyond LDL-C lowering: distinct molecular sphingolipids are good indicators of proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency.
38 Kaikkonen JE et al. Childhood serum fatty acid quality is associated with adult carotid artery intima media thickness in women but not in men.
39 Khanna A et al. Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells.
40 Kivelä AJ et al. Carbonic anhydrase IX in malignant pleural mesotheliomas: a potential target for anti-cancer therapy.
41 Kleber ME et al. Genome-Wide Association Study Identifies 3 Genomic Loci Significantly Associated With Serum Levels of Homoarginine: The AtheroRemo Consortium.
42 Korhonen T et al. The impact of lobular and ductal breast cancer histology on the metastatic behavior and long term survival of breast cancer patients.
43 Koskela J et al. Association of resting heart rate with cardiovascular function: a cross-sectional study in 522 Finnish subjects.
44 Kote-Jarai Z et al. Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.
45 Kresanov P et al. The associations of oxidized high-density lipoprotein lipids with risk factors for atherosclerosis: The Cardiovascular Risk in Young Finns Study.
46 Kujala UM et al. Long-term leisure-time physical activity and serum metabolome.
47 Kuusisto KM et al. Copy number variation analysis in familial BRCA1/2-negative Finnish breast and ovarian cancer.
48 Kämppä N et al. Vascular cell adhesion molecule 1, soluble Fas and hepatocyte growth factor as predictors of mortality in nonagenarians: the Vitality 90+ study.
49 Köttgen A et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
50 Lagerstedt M et al. Childhood lichen sclerosus-a challenge for clinicians.
51 Lahtinen A et al. Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population.
52 Laitinen V et al. HOXB13 G84E mutation in Finland: population-based analysis of prostate, breast, and colorectal cancer risk.
53 Laurila EM, Kallioniemi A. The diverse role of miR-31 in regulating cancer associated phenotypes.
54 Laurila PP et al. Genomic, transcriptomic, and lipidomic profiling highlights the role of inflammation in individuals with low high-density lipoprotein cholesterol.
55 Laurila R et al. The expression patterns of gremlin 1 and noggin in normal adult and tumor tissues.
56 Lehmusvaara S et al. Goserelin and bicalutamide treatments alter the expression of microRNAs in the prostate.
57 Leinonen KA et al. Loss of PTEN Is Associated with Aggressive Behavior in ERG-Positive Prostate Cancer.
58 Leppiniemi J et al. The highly dynamic oligomeric structure of bradavidin II is unique among avidin proteins.
59 Lisko I et al. Are body mass index, waist circumference and waist-to-hip ratio associated with leptin in 90-year-old people?
60 Lohi O et al. Lapsuusiän leukemia.
61 Markus HS et al. Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.
62 Mäkelä KM et al. Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.
63 Määttä K et al. Contribution of SLC7A1 genetic variant to hypertension, the TAMRISK study.
64 Määttä KM et al. A functional variant in the serine-threonine kinase coding gene is associated with hypertension: a case-control study in a Finnish population, the Tampere adult population cardiovascular risk study.
65 Nettleton JA et al. Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohort.
66 Nordfors K et al. Carbonic Anhydrase IX in Adult and Pediatric Brain Tumors.
67 Nurminen R et al. Fine mapping of 11q13.5 identifies regions associated with prostate cancer and prostate cancer death.
68 Oksala N et al. Association of Neuroimmune Guidance Cue Netrin-1 and Its Chemorepulsive Receptor UNC5B With Atherosclerotic Plaque Expression Signatures and Stability in Human(s): Tampere Vascular Study (TVS).
69 Oksala N et al. Complementary prediction of cardiovascular events by estimated apo- and lipoprotein concentrations in the working age population. The Health 2000 Study.
70 Pan P et al. Cloning, characterization, and sulfonamide and thiol inhibition studies of an a-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease.
71 Pan P et al. Anion inhibition studies of the a-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease.
72 Parker BC et al. The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma.
73 Parsa A et al. Common variants in mendelian kidney disease genes and their association with renal function.
74 Paternoster L et al. Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.
75 Pessi T et al. Bacterial signatures in thrombus aspirates of patients with myocardial infarction.
76 Pessi T et al. Response to letters regarding article, "Bacterial signatures in thrombus aspirates of patients with myocardial infarction".
77 Pitkänen AM et al. Is There an Association between Temperament and Apolipoprotein E? A Replication of a 1993 Young Finns Study.
78 Pohjoismäki J et al. Postnatal cardiomyocyte growth and mitochondrial reorganization cause multiple changes in the proteome of human cardiomyocytes .
79 Pollheimer P et al. Reversible biofunctionalization of surfaces with a switchable mutant of avidin.
80 Pyysalo MJ et al. The connection between ruptured cerebral aneurysms and odontogenic bacteria.
81 Rainio J et al. Immunoassay for ethyl glucuronide in vitreous humor: a new tool for postmortem diagnostics of alcohol use.
82 Raitakari OT et al. Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk.
83 Raitoharju E. MicroRNA-616 and atherosclerosis - A commentary on the paper by Liu et al .
84 Raitoharju E et al. MicroRNAs in the atherosclerotic plaque.
85 Raitoharju E et al. A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.
86 Randall JC et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
87 Rauhala HE et al. Silencing of the ARP2/3 complex disturbs pancreatic cancer cell migration.
88 Rauhio A et al. Association of the FTO and ADRB2 genes with body composition and fat distribution in obese women.
89 Renko J et al. Bacterial DNA signatures in carotid atherosclerosis represent both commensals and pathogens of skin origin.
90 Richardson K et al. Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site.
91 Rietveld CA et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
92 Saarelainen SK et al. Predictive value of serum human epididymis protein 4 and cancer antigen 125 concentrations in endometrial carcinoma.
93 Sibolt G et al. Post-stroke depression and depression-executive dysfunction syndrome are associated with recurrence of ischaemic stroke.
94 Sibolt G et al. Poststroke dementia is associated with recurrent ischaemic stroke.
95 Silbernagel G et al. High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis.
96 Siltanen S et al. ARLTS1 and prostate cancer risk--analysis of expression and regulation.
97 Simpson C et al. Genetic heterogeneity in Finnish hereditary prostate cancer using ordered subset analysis.
98 Skilton MR et al. Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing fetal origins of disease? The Cardiovascular Risk in Young Finns Study.
99 Smith CE et al. Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies.
100 Solakivi T et al. Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro.
101 Staff S et al. Preservation of nucleic acids and tissue morphology in paraffin-embedded clinical samples: comparison of five molecular fixatives.
102 Stephens SH et al. Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.
103 Stoll G et al. Deletion of TOP3ß, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders.
104 Syrjänen L et al. Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new a-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster.
105 Syrjänen L et al. Cloning, characterization, and inhibition studies of a ß-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis.
106 Tanaka T et al. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.
107 Taskinen B et al. Zebavidin - an avidin-like protein from zebrafish.
108 Taverniti V et al. S-layer protein mediates the stimulatory effect of Lactobacillus helveticus MIMLh5 on innate immunity.
109 Tolvanen ME et al. Analysis of evolution of carbonic anhydrases IV and XV reveals a rich history of gene duplications and a new group of isozymes.
110 Tossavainen H et al. Resonance assignments of the 56 kDa chimeric avidin in the biotin-bound and free forms.
111 Tuohimaa P, Järvilehto M. A Unified Hypothesis for the Pathogenesis of Chronic Obstructive Pulmonary Disease and Atherosclerosis: The Role of Microvascular Flow Insufficiency and Functional Hypoxia.
112 Tuomisto S et al. Time-dependent post mortem changes in the composition of intestinal bacteria using real-time quantitative PCR.
113 Tuomisto S et al. Evaluation of postmortem bacterial migration using culturing and real-time quantitative PCR.
114 Turpeinen H et al. Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor ß1a (TGFß1a).
115 Tyynelä P et al. Age-dependent interaction of apolipoprotein E gene with eastern birthplace in Finland affects severity of coronary atherosclerosis and risk of fatal myocardial infarction-Helsinki Sudden Death Study.
116 Urbanucci et al. The Effect of AR Overexpression on Androgen Signaling in Prostate Cancer .
117 van Der Loos Mj et al. The molecular genetic architecture of self-employment.
118 Varmavuo V et al. CD34+ cell subclasses and lymphocyte subsets in blood grafts collected after various mobilization methods in myeloma patients.
119 Verhoeven VJ et al. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
120 Viikki M et al. BDNF polymorphism rs11030101 is associated with the efficacy of electroconvulsive therapy in treatment-resistant depression.
121 Viiri LE et al. Smooth muscle cells in human atherosclerosis: proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease.
122 Vimaleswaran KS et al. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.
123 Wessels HJ et al. Analysis of 953 human proteins from a mitochondrial HEK293 fraction by complexome profiling.
124 Willer CJ et al. Discovery and refinement of loci associated with lipid levels.
125 Würtz P et al. Lipoprotein subclass profiling reveals pleiotropy in the genetic variants of lipid risk factors for coronary heart disease: a note on mendelian randomization studies.
126 Würtz P et al. Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults.
127 Xu J et al. HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).
128 Yaghootkar H et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.
129 Ylilauri M et al. Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.
Kliininen kemia Clinical Chemistry
Julkaisutietokanta 19.1.2016 Publications Data Base 19.1.2016