Kliininen kemia
Clinical Chemistry

Julkaisut 2015
Publications 2015

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1 Ahtiainen K et al. Effects of chitosan and bioactive glass modifications of knitted and rolled polylactide-based 96/4L/D scaffolds on chondrogenic differentiation of adipose stem cells.
2 Airaksinen J et al. Neighborhood effects in depressive symptoms, social support, and mistrust: Longitudinal analysis with repeated measurements.
3 Alafeefy AM et al. A new class of quinazoline-sulfonamides acting as efficient inhibitors against the a-carbonic anhydrase from Trypanosoma cruzi.
4 Amin AL et al. Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
5 Amin AL Olama A et al. Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci.
6 Andre K et al. SERT and NET polymorphisms, temperament and antidepressant response.
7 Annala M et al. Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer.
8 Arnott C et al. Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study.
9 Artigas MS et al. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.
10 Aspatwar A et al. Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish.
11 Aspatwrt A et al. Carbonic Anhydrase XII.
12 Auer S et al. Rapid and sensitive detection of norovirus antibodies in human sserum with a biolayer interferometry biosensor.
13 Barfeld SJ et al. Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer.
14 Burgner DP et al. Infection-Related Hospitalization in Childhood and Adult Metabolic Outcomes.
15 Burgner DP et al. Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: The Cardiovascular Risk in Young Finns Study.
16 Danaei G et al. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331,288 participants.
17 Dashti HS et al. Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants.
18 Dashti HS et al. Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits.
19 de Moor Mh et al. Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.
20 Dobbs K et al. Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections.
21 Elovainio M et al. Activated immune-inflammatory pathways are associated with long-standing depressive symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study.
22 Fischer D et al. MiRNA Profiles in Lymphoblastoid Cell Lines of Finnish Prostate Cancer Families.
23 Fretts AM et al. Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians.
24 Gorski M et al. Genome-wide association study of kidney function decline in individuals of European descent.
25 Gottlieb DJ et al. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study.
26 Gundem G et al. The evolutionary history of lethal metastatic prostate cancer.
27 Haataja P et al. Prognostic implications of intraventricular conduction delays in a general population: The Health 2000 Survey.
28 Kolasa M, Basnyat P. Analysis of apoptosis-related genes in patients with clinically isolated syndrome and their association with conversion to multiple sclerosis.
29 Hartiala O et al. Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study.
30 Helajärvi H et al. Television viewing and fatty liver in early midlife. The Cardiovascular Risk in Young Finns Study.
31 Hernesniemi J et al. Predicting sudden cardiac death using common genetic risk variants for coronary artery disease.
32 Horikoshi M et al. Discovery and fine-mapping of glycaemic and obesity-related trait loci using high-density imputation .
33 Hussain SM et al. Impact of fetal growth and preterm birth on the retinal microvasculature in mid-adulthood.
34 Jacobsen KK et al. Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder.
35 Joshi P et al. Directional dominance on stature and cognition in diverse human populations.
36 Juonala M et al. Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns Study.
37 Juonala M et al. Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery Criteria.
38 Juuti-Uusitalo K et al. Effects of Cytokine Activation and Oxidative Stress on the Function of the Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells.
39 Kaikkonen JE et al. Factors associated with six-year weight change in young and middle-aged adults in the Young Finns Study.
40 Karhunen P, Meinander T. Coronary artery disease: Complex association between height and CHD - size matters.
41 Kato N et al. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
42 Kaukoniemi K et al. Epigenetically altered miR-193b targets cyclin D1 in prostate cancer.
43 Kautto M et al. Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.
44 Khanna A et al. CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.
45 Klemettilä JP et al. Association study of the HTR2C, leptin and adiponectin genes and serum marker analyses in clozapine treated long-term patients with schizophrenia.
46 Koho T et al. His-tagged norovirus-like particles: A versatile platform for cellular delivery and surface display.
47 Koskela S et al. Endothelial Nitric Oxide Synthase G894T Polymorphism Associates with Disease Severity in Puumala Hantavirus Infection.
48 Kresanov P et al. Paraoxonase-1 and oxidized lipoprotein lipids. The Cardiovascular Risk in Young Finns Study.
49 Kunnas T et al. NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK stud.
50 Nikkari ST. Association of Zinc Finger, C3HC-Type Containing 1 (ZC3HC1) rs11556924 Genetic Variant With Hypertension in a Finnish Population, the TAMRISK Study.
51 Kunz M et al. Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.
52 Kurra V et al. Effects of oxonic acid-induced hyperuricemia on masenteric artery tone and cardic load in experimental renal insufficiensy.
53 la Regina G et al. Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors.
54 Laiho JE et al. Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology.
55 Laine O et al. Hantavirus infection-induced thrombocytopenia triggers increased production but associates with impaired aggregation of platelets except for collagen.
56 Laitinen V et al. Fine-mapping the 2q37 and 17q11.2-q22 loci for novel genes and sequence variants associated with a genetic predisposition to prostate cancer.
57 Lehtonen S et al. Efficient preparation of shuffled DNA libraries through recombination (Gateway) cloning.
58 Leinonen J, Parkkila S. Secreted Carbonic Anhydrase Isoenzyme VI.
59 Li Q et al. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.
60 Locke AE et al. Genetic studies of body mass index yield new insights for obesity biology.
61 Loukola A et al. A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism.
62 Malik R et al. Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.
63 Mantere T et al. Finnish Fanconi anemia mutations and hereditary predisposition to breast and prostate cancer.
64 Martens-Uzunova ES et al. C/D-box snoRNA-derived RNA production is associated with malignant transformation and metastatic progression in prostate cancer.
65 Martiskainen H et al. Effects of Alzheimer's disease-associated risk Loci on cerebrospinal fluid biomarkers etc.
66 Min X et al. Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2.
67 Minkkinen M et al. Prognostic capacity of a clinically indicated exercise test for cardiovascular mortality is enhanced by combined analysis of exercise capacity, heart rate recovery and T-wave alternans.
68 Mullola S et al. Adulthood temperament and educational attainment: A population-based cohort study .
69 Murtola TJ et al. Polymorphisms of Genes Involved in Glucose and Energy Metabolic Pathways and Prostate Cancer: Interplay with Metformin.
70 Mäkelä KM. Genetic Basis of Atherosclerosis, Ischemic Stroke and Lipoprotein Oxidation with Special Reference to HDAC9 and MMP12 Genes.
71 Nelson CP et al. Genetically determined height and coronary artery disease.
72 Nettleton JA et al. Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry.
73 Nikkari ST et al. Functional Inducible Nitric Oxide Synthase Gene Variants Associate With Hypertension: A Case-Control Study in a Finnish Population-The TAMRISK Study.
74 Nikpay M et al. A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
75 Oksala N et al. Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds.
76 Orlowski A et al. PIP2 and Talin Join Forces to Activate Integrin.
77 Pawlowski A et al. The Minor Capsid Protein VP11 of Thermophilic Bacteriophage P23-77 Facilitates Virus Assembly by Using Lipid-Protein Interactions.
78 Penttilä I et al. Hemoglobin A1c reported in units and diagnostic cut-offs in relation to the international recommendations.
79 Pers T et al. Biological interpretation of genome-wide association studies using predicted gene functions.
80 Viiri LE et al. Interleukin-6 and microRNA profiles induced by oral bacteria in human atheroma derived and healthy smooth muscle cells.
81 Peyrot WJ et al. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
82 Pitkäniemi J et al. Effectiveness of screening for colorectal cancer with a faecal occult-blood test, in Finland.
83 Pärssinen J et al. Enhancement of adhesion and promotion of osteogenic differentiation of human adipose stem cells by poled electroactive poly(vinylidene fluoride).
84 Rahmioglu N et al. Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci.
85 Raitoharju E et al. MicroRNAs in the atherosclerotic plaque .
86 Rane JK et al. MicroRNA expression profile of primary prostate cancer stem cells as a source of biomarkers and therapeutic targets.
87 Rane JK et al. Construction of therapeutically relevant human prostate epithelial fate map by utilising miRNA and mRNA microarray expression data.
88 Rautalahti Matti. Duodecim ja Suomen Lääketieteen Säätiö hakevat uusia tutkimusavauksia.
89 Ray S et al. Neutralized chimeric avidin binding at a reference biosensor surface.
90 Ribeiro C et al. Dynamic piezoelectric stimulation enhances osteogenic differentiation of human adipose stem cells.
91 Rinne P et al. Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humansl.
92 Ritchie S et al. The biomarker GlycA is associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection .
93 Sabin MA et al. Longitudinal investigation of adenovirus 36 seropositivity and human obesity: the Cardiovascular Risk in Young Finns Study.
94 Sabin MA et al. Insulin and BMI as predictors of adult type 2 diabetes mellitus.
95 Salo PP et al. Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population.
96 Sawyer SL et al. Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype.
97 Scaravilli M et al. MiR-1247-5p is overexpressed in castration resistant prostate cancer and targets MYCBP2.
98 Serlachius A et al. Is dispositional optimism or dispositional pessimism predictive of ideal cardiovascular health? The Young Finns Study.
99 Shungin D et al. New genetic loci link adipose and insulin biology to body fat distribution.
100 Sibolt G et al. Severe cerebral white matter lesions in ischemic stroke patients are associated with less time spent at home and early institutionalization.
101 Solakivi T. Contribution of fatty acid transporter (CD36) genetic variant rs1761667 to body mass index, the TAMRISK study.
102 Stegeman S et al. A large scale analysis of genetic variants within putative miRNA binding sites in prostate cancer.
103 Suomela E et al. Prevalence and determinants of fatty liver in normal-weight and overweight young adults. The Cardiovascular Risk in Young Finns Study.
104 Surakka I et al. The impact of low-frequency and rare variants on lipid levels.
105 Vullo D, Supuran CT. The ß-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides.
106 Syrjänen L et al. ß carbonic anhydrase is required for female fertility in Drosophila melanogaster.
107 Tapp RJ et al. Impact of blood pressure on retinal microvasculature architecture across the lifespan: the Young Finns Study.
108 Tesori V et al. The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing.
109 The Coffee And Caffeine Genetic Consortium et al. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
110 Turpeinen H et al. A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.
111 van Der Valk Rj et al. A novel common variant in DCST2 is associated with length in early life and height in adulthood.
112 Vassilev B et al. Elevated Levels of StAR-Related Lipid Transfer Protein 3 Alter Cholesterol Balance and Adhesiveness of Breast Cancer Cells: Potential Mechanisms Contributing to Progression of HER2-Positive Breast Cancers.
113 Voipio AJ et al. Determinants of serum 25(OH)D concentration in young and middle-aged adults. The Cardiovascular Risk in Young Finns Study.
114 Wang Q et al. Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates.
115 Winkler TW et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
116 Würtz P et al. Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts.
117 Ylipää A et al. Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer.
118 Zimmermann E et al. Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults.
119 Zolfaghari EMAMEH R et al. Ascaris lumbricoides ß carbonic anhydrase: a potential target enzyme for treatment of ascariasis.
120 Zolfaghari Emameh R et al. Drosophila melanogaster: a model organism for controlling Dipteran vectors and pests.
121 Zoni E et al. miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of av- and a6-Integrin Expression.

Kliininen kemia Clinical Chemistry
Julkaisutietokanta 30.11.2016 Publications Data Base 30.11.2016