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1 Taipale H, Tanskanen A, Mehtälä J, Vattulainen P, Correll CU, Tiihonen J. 20-year follow-up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (FIN20). World Psychiatry 2020:19(1):61-68.
2 Tiihonen J, Tanskanen A, Taipale H. 20-Year Nationwide Follow-Up Study on Discontinuation of Antipsychotic Treatment in First-Episode Schizophrenia. Am J Psychiatry 2018:175(8):765-773.
3 Kupila J, Kärkkäinen O, Laukkanen V, Häkkinen M, Kautiainen H, Tiihonen J, Storvik M. (3H)Ifenprodil binding in post-mortem brains of cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study . Psychiatry Res 2015:231(3):197-201.
4 Sun L, Lukkarinen L, Noppari T, Nazari-Farsani S, Putkinen V, Seppälä K, Hudson M, Tani P, Lindberg N, Karlsson HK, Hirvonen J, Salomaa M, Venetjoki N, Lauerma H, Tiihonen J, Nummenmaa L. Aberrant motor contagion of emotions in psychopathy and high-functioning autism. Cereb Cortex 2022:33(2):374-384.
5 Lukkarinen L, Tuisku J, Sun L, Helin S, Karlsson HK, Venetjoki N, Salomaa M, Rautio P, Hirvonen J, Lauerma H, Tiihonen J, Nummenmaa L. Aberrant type 2 dopamine receptor availability in violent offenders with psychopathy. Neuroimage 2024:297:120724.
6 Koponen M, Lavikainen P, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. Accumulation of Hospital Days Among Antipsychotic Initiators With Alzheimer's Disease. J Am Med Dir Assoc 2019:20(12):1488-1494.e3.
7 Terevnikov V, Stenberg J, Tiihonen J, Burkin M, Joffe G. Add-on mirtazapine improves orgasmic functioning in patients with schizophrenia treated with first-generation antipsychotics. Nord J Psychiatry 2017:71(1):77-80.
8 Lintunen J, Lähteenvuo M, Tiihonen J, Tanskanen A, Taipale H. Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia. NPJ Schizophr 2021:7(1):1.
9 Forsman J, Taipale H, Masterman T, Tiihonen J, Tanskanen A. Adherence to psychotropic medication in completed suicide in Sweden 2006-2013: a forensic-toxicological matched case-control study. Eur J Clin Pharmacol 2019:75(10):1421-1430.
10 Taipale H, Tanskanen A, Koponen M, Tolppanen AM, Tiihonen J, Hartikainen S. Agreement between PRE2DUP register data modeling method and comprehensive drug use interview among older persons. Clin Epidemiol 2016:8:363-371.
11 Lindsberg PJ, Castrén E, ..., Isometsä E, Kalso E, Marttunen M, Pihko H, Tienari P, Wartiovaara A, Jäkälä P, Kälviäinen R, Soininen H, Tiihonen J, Karlsson H, Rinne J, Roine RO, Elovaara I, Tamminen T, Öhman J, Majamaa K, Hari R. Aivosairaudet ovat kalleimmat kansantautimme. Duodecim 2014:130(17):1721-30.
12 Lehikoinen AI, Kärkkäinen OK, Lehtonen MAS, Auriola SOK, Hanhineva KJ, Heinonen ST. Alcohol and substance use are associated with altered metabolome in the first trimester serum samples of pregnant mothers . Eur J Obstet Gynecol Reprod Biol 2018:223:79-84.
13 Lintunen J, Lähteenvuo M, Tanskanen A, Tiihonen J, Taipale H. Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study. J Affect Disord 2022:313:43-48.
14 Laukkanen V, Laukkanen V. Alterations in the neurotransmitter receptor binding densities in cloninger type 1 and 2 alcoholics. Doctoral dissertation. Kuopio: University of Eastern Finland, 2016. Publications of the University of Eastern Finland. Dissertations in Health Sciences 355. 76 p.
15 Taipale H, Tolppanen A-M, Purhonen M, Tanskanen A, Ahonen R, Tiihonen J, Hartikainen S. Alueelliset erot sairaalapäivissä ja lääkekustannuksissa Alzheimerin tautia sairastavilla ja verokeilla. Suomen Lääkärilehti 2016:71(22):1613-1619.
16 Juhola L, Taipale H, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A-M. Alzheimer-potilaat ja psyykenlääkkeiden käyttö 2005-2011. Suomen Lääkärilehti 2019:74(10):609-616.
17 Kärkkäinen O, Kupila J, Häkkinen M, Laukkanen V, Tupala E, Kautiainen H, Tiihonen J, Storvik M. AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study. Psychiatry Res Neuroimaging 2013:214:429-434.
18 Kivimies K. Amphetamine, Cannabis and Opioid Use Disorders in Forensic Patients and in Schizophrenia. Doctoral dissertation. Kuopio: University of Eastern Finland, 2018. Publications of the University of Eastern Finland. Dissertations in Health Sciences 468. 52 p.
19 Lindner P, Flodin P, Larm P, Budhiraja M, Savic-Berglund I, Jokinen J, Tiihonen J, Hodgins S. Amygdala-orbitofrontal structural and functional connectivity in females with anxiety disorders, with and without a history of conduct disorder. Sci Rep 2018:8(1):1101.
20 Paljarvi T, Forton J, Luciano S, Herttua K, Fazel S. Analysis of Neuropsychiatric Diagnoses After Montelukast Initiation. JAMA Netw Open 2022:5(5):e2213643.
21 Borger Rognli E, Taipale H, Hjorthøj C, Mittendorfer-Rutz E, Bramness JG, Heiberg IH, Niemelä S. Annual incidence of substance-induced psychoses in Scandinavia from 2000 to 2016. Psychol Med 2023:53(11):5246-5255.
22 Lampela P, Tolppanen AM, Tanskanen A, Tiihonen J, Hartikainen S, Taipale H. Anticholinergic Exposure and Risk of Pneumonia in Persons with Alzheimer's Disease: A Nested Case-Control Study. J Alzheimers Dis 2017:56(1):119-128.
23 Taipale H1, Tanskanen A, Koponen M, Tolppanen AM, Tiihonen J, Hartikainen S. Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study. Int Clin Psychopharmacol 2014:29(4):216-23.
24 Kieseppä V, Markkula N, Taipale H, Holm M, Jokela M, Suvisaari J, Tanskanen A, Gissler M, Lehti V. Antidepressant use among immigrants with depressive disorder living in Finland: A register-based study. J Affect Disord 2022:299:528-535.
25 Torvinen-Kiiskinen S, Tolppanen AM, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Taipale H. Antidepressant use and risk of hip fractures among community-dwelling persons with and without Alzheimer's disease. Int J Geriatr Psychiatry 2017:32(12):e107-e115.
26 Sarycheva T, Lavikainen P, Taipale H, Tiihonen J, Tanskanen A, Hartikainen S, Tolppanen A. Antiepileptic drug use and mortality among community-dwelling persons with Alzheimer disease. Neurology 2020:94(20):e2099-e2108.
27 Sarycheva T, Lavikainen P, Taipale H, Tiihonen J, Tanskanen A, Hartikainen S, Tolppanen A-M. Antiepileptic Drug Use and the Risk of Stroke Among Community-Dwelling People With Alzheimer Disease: A Matched Cohort Study. J Am Heart Assoc 2018:7(18):e009742.
28 Taipale H, Lampela P, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. Antiepileptic Drug Use Is Associated with an Increased Risk of Pneumonia Among Community-Dwelling Persons with Alzheimer's Disease-Matched Cohort Study. J Alzheimers Dis 2019:68(1):127-136.
29 Lavikainen P, Taipale H, Tanskanen A, Koponen M, Tiihonen J, Hartikainen S, Tolppanen A. Antiepileptic Drugs and Accumulation of Hospital Days Among Persons With Alzheimer's Disease. J Am Med Dir Assoc 2019:20(6):751-758.
30 Luykx JJ, Tiihonen J. Antipsychotic discontinuation: mind the patient and the real-world evidence. Lancet Psychiatry 2021:8(7):555-557.
31 Taipale H1, Koponen M, Tanskanen A, Tolppanen AM, Tiihonen J, Hartikainen S. Antipsychotic doses among community-dwelling persons with Alzheimer disease in Finland. J Clin Psychopharmacol 2014:34(3):435-40.
32 Cederlöf E, Holm M, Taipale H, Tiihonen J, Tanskanen A, Lähteenvuo M, Lahdensuo K, Kampman O, Wegelius A, Isometsä E, Kieseppä T, Palotie A, Suvisaari J, Paunio T, et al. Antipsychotic medications and sleep problems in patients with schizophrenia. Schizophr Res 2024:267:230-238.
33 Luykx JJ, Tiihonen J, Taipale H. Antipsychotic Monotherapy vs Polytherapy for Pneumonia Risk-Reply. JAMA Psychiatry 2024:81(12):1278-1279.
34 Taipale H1, Koponen M1, Tanskanen A2, Tolppanen AM3, Tiihonen J, Hartikainen S. Antipsychotic Polypharmacy among a Nationwide Sample of Community-Dwelling Persons with Alzheimer's Disease. J Alzheimers Dis 2014:41(4):1223-8.
35 Lähteenvuo M, Tiihonen J. Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations. Drugs 2021:81(11):1273-1284.
36 Torniainen M, Mittendorfer-Rutz E, Tanskanen A, Björkenstam C, Suvisaari J, Alexanderson K, Tiihonen J. Antipsychotic Treatment and Mortality in Schizophrenia. Schizophr Bull 2015:41(3):656-63.
37 Spaton Goppers J, Mittendorfer-Rutz E, Cullen AE, Jamil de Montgomery C, Tanskanen A, Norredam M, Taipale H. Antipsychotic treatment patterns in refugees and their Swedish-born peers with first-episode non-affective psychosis: findings from the REMAIN study. BJPsych Open 2023:9(3):e57.
38 Taipale H, Puranen A, Mittendorfer-Rutz E, Tiihonen J, Tanskanen A, Cervenka S, Lähteenvuo M. Antipsychotic use among persons with schizophrenia in Sweden and Finland, trends and differences. Nord J Psychiatry 2021:75(5):315-322.
39 Denissoff A, Taipale H, Tiihonen J, Di Forti M, Mittendorfer-Rutz E, Tanskanen A, Mustonen A, Niemelä S. Antipsychotic Use and Psychiatric Hospitalization in First-Episode Non-affective Psychosis and Cannabis Use Disorder: A Swedish Nationwide Cohort Study. Schizophr Bull 2024:50(6):1287-1294.
40 Taipale H, Solmi M, Lähteenvuo M, Tanskanen A, Correll CU, Tiihonen J. Antipsychotic use and risk of breast cancer in women with schizophrenia: a nationwide nested case-control study in Finland. Lancet Psychiatry 2021:8(10):883-891.
41 Solmi M, Lähteenvuo M, Tanskanen A, Corbeil O, Mittendorfer-Rutz E, Correll CU, Tiihonen J, Taipale H. Antipsychotic Use and Risk of Breast Cancer in Women With Severe Mental Illness: Replication of a Nationwide Nested Case-Control Database Study. Schizophr Bull 2024:50(6):1471-1481.
42 Tolppanen AM, Koponen M, Tanskanen A, Lavikainen P, Sund R, Tiihonen J, Hartikainen S, Taipale H. Antipsychotic Use and Risk of Hospitalization or Death Due to Pneumonia in Persons With and Those Without Alzheimer Disease. Chest 2016:150(6):1233-1241.
43 Solmi M, Lähteenvuo M, Correll CU, Tanskanen A, Tiihonen J, Taipale H. Antipsychotic Use and Risk of Low-Energy Fractures in People With Schizophrenia: A Nationwide Nested Case-Control Study in Finland. Schizophr Bull 2023:49(1):78-89.
44 Koponen M, Rajamaki B, Lavikainen P, Bell JS, Taipale H, Tanskanen A, Hartikainen S, Tolppanen A. Antipsychotic Use and Risk of Stroke Among Community-Dwelling People With Alzheimer's Disease. J Am Med Dir Assoc 2022:23(6):1059-1065.e4.
45 Koponen M, Taipale H, Lavikainen P, Tanskanen A, Tiihonen J, Tolppanen A, Ahonen R, Hartikainen S. Antipsychotic Use and the Risk of Hip Fracture Among Community-Dwelling Persons With Alzheimer's Disease. J Clin Psychiatry 2017:78(3):e257-e263.
46 Orsel K, Taipale H, Raatikainen S, Lampela P, Tolppanen A-M, Koponen M, Tanskanen A, Tiihonen J, Gardarsdottir H, Hartikainen S. Antipsychotic Use and the Risk of Initiating Medication for Benign Prostate Hyperplasia in Persons With Alzheimer Disease: A Matched Cohort Study. J Clin Psychopharmacol 2018:38(5):494-497.
47 Taipale H, Mittendorfer-Rutz E, Alexanderson K, Majak M, Mehtälä J, Hoti F, Jedenius E, Enkusson D, Leval A, Sermon J, Tanskanen A, Tiihonen J. Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia. Schizophr Res 2018:197:274-280.
48 Solmi M, Tiihonen J, Lähteenvuo M, Tanskanen A, Correll CU, Taipale H. Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study. Schizophr Bull 2022:48(1):166-175.
49 Fiorito AM, Aleman A, Blasi G, Bourque J, Cao H, Chan RC, Chowdury A, Conrod P, Diwadkar VA, Goghari VM, Guinjoan S, Gur RE, Gur RC, Kwon JS, Lieslehto J, Lukow PB, Meyer-Lindenberg A, Modinos G, Quarto T, Spilka MJ, et al. Are Brain Responses to Emotion a Reliable Endophenotype of Schizophrenia? An Image-Based Functional Magnetic Resonance Imaging Meta-analysis. Biol Psychiatry 2023:93(2):167-177.
50 Husso M, Sipola P, Kuittinen T, Manninen H, Vainio P, Hartikainen J, Saarakkala S, Töyräs J, Kuikka J. Assessment of myocardial perfusion with MRI using a modified dual bolus method. Physiol Meas 2014:35(4):533-547.
51 Taipale H, Taylor M, Lähteenvuo M, Mittendorfer-Rutz E, Tanskanen A, Tiihonen J. Association between GLP-1 receptor agonist use and worsening mental illness in people with depression and anxiety in Sweden: a national cohort study. Lancet Psychiatry 2026:13(4):327-335.
52 Olubamwo O, Onyeka IN, Aregbesola A, Ronkainen K, Tiihonen J, Föhr J, Kauhanen J. Association between route of illicit drug administration and hospitalizations for infective endocarditis. SAGE Open Med 2017:5:2050312117740987.
53 Onyeka IN, Basnet S, Beynon CM, Tiihonen J, Tiihonen J, Föhr J, Kauhanen J. Association between routes of drug administration and all-cause mortality among drug users. J Subst Use 2016:21(6):559-565.
54 Tiihonen J, Halonen P, Tiihonen L, Kautiainen H, Storvik M, Callaway J. The association of ambient temperature and violent crime. Sci Rep 2017:7(1):6543.
55 Mäkipelto V, Tuulio-Henriksson A, Hakulinen C, Niemelä S, Lähteenvuo M, Wegelius A, Kieseppä T, Isometsä E, Tiihonen J, Kampman O, Lahdensuo K, Mazumder A, Suvisaari J, Holm M. Association of antidepressant and benzodiazepine use, and anticholinergic burden with cognitive performance in schizophrenia. Schizophr Res 2024:266:118-126.
56 Tiihonen J, Taipale H, Mehtälä J, Vattulainen P, Correll CU, Tanskanen A. Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia. JAMA Psychiatry 2019:76(5):499-507.
57 Ojansuu I, Forsman J, Kautiainen H, Seppänen A, Tiihonen J, Lähteenvuo M. Association of duration of treatment on post-discharge mortality in forensic psychiatric patients in Finland. Front Psychiatry 2024:15:1372687.
58 Chen J, Mittendorfer-Rutz E, Taipale H, Rahman S, Niederkrotenthaler T, Klimek P. Association of medication clusters and subsequent labor market marginalization in refugee and Swedish-born young adults with common mental disorders in Sweden. Eur Child Adolesc Psychiatry 2024:33(3):897-907.
59 Toimela JS, Halt AH, Kerkelä M, Kampman O, Suvisaari J, Kieseppä T, Lähteenvuo M, Tiihonen J, Ahola-Olli A, Veijola J, Holm M, Holm M. Association of obesity to reaction time and visual memory in schizophrenia. Schizophr Res Cogn 2024:37:100316.
60 Heikkinen M, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Lähteenvuo M, Tiihonen J. Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13 965 Patients. JAMA Psychiatry 2023:80(1):31-39.
61 Lieslehto J, Tiihonen J, Lähteenvuo M, Mittendorfer-Rutz E, Tanskanen A, Taipale H. Association of pharmacological treatments and real-world outcomes in borderline personality disorder. Acta Psychiatr Scand 2023:147(6):603-613.
62 Tarvainen A, Hartikainen S, Taipale H, Tanskanen A, Koponen M, Tolppanen AM. Association of recent hospitalisation with antidepressant initiation among community dwellers with Alzheimer's disease. Int J Geriatr Psychiatry 2021:36(7):1075-1084.
63 Mittendorfer-Rutz E, Härkänen T, Tiihonen J, Haukka J. Association of Socio-Demographic Factors, Sick-Leave and Health Care Patterns with the Risk of Being Granted a Disability Pension among Psychiatric Outpatients with Depression. PLoS ONE 2014:9(6):e99869.
64 Lundberg J, Cars T, Lööv S, Söderling J, Sundström J, Tiihonen J, Leval A, Gannedahl A, Björkholm C, Själin M, Hellner C. Association of Treatment-Resistant Depression With Patient Outcomes and Health Care Resource Utilization in a Population-Wide Study. JAMA Psychiatry 2023:80(2):167-175.
65 Herttua K, Scola G, Paljarvi T, Fazel S. Associations between antidepressants and risk of suicidal behavior and violent crimes in personality disorder. Eur Psychiatry 2025:68(1):e28.
66 Lähteenvuo M, Luykx JJ, Taipale H, Mittendorfer-Rutz E, Tanskanen A, Batalla A, Tiihonen J. Associations between antipsychotic use, substance use and relapse risk in patients with schizophrenia: real-world evidence from two national cohorts. Br J Psychiatry 2022:221(6):758-765.
67 Herttua K, Crawford M, Paljarvi T, Fazel S. Associations between antipsychotics and risk of violent crimes and suicidal behaviour in personality disorder. Evid Based Ment Health 2022:25(e1):e58-e64.
68 Bendre M, Comasco E, Checknita D, Tiihonen J, Hodgins S, Nilsson KW. Associations between MAOA-uVNTR genotype, maltreatment, MAOA methylation, and alcohol consumption in young adult males. Alcohol Clin Exp Res 2018:42(3):508-519.
69 Checknita D, Tiihonen J, Hodgins S, Nilsson KW. Associations of age, sex, sexual abuse, and genotype with monoamine oxidase a gene methylation. J Neural Transm 2021:128(11):1721-1739.
70 Cullen AE, de Montgomery CJ, Pettersson E, Akhtar A, Norredam M, Taipale H, Mittendorfer-Rutz E. Associations of migrant and refugee status with physical comorbidity and mortality among young adults with incident non-affective psychotic disorders. BMC Public Health 2025:25(1):2680.
71 Checknita D, Ekström TJ, Comasco E, Nilsson KW, Tiihonen J, Hodgins S. Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women. J Neural Transm 2018:125(7):1053-1064.
72 Lindner P, Flodin P, Budhiraja M, Savic I, Jokinen J, Tiihonen J, Hodgins S. Associations of Psychopathic Traits With Local and Global Brain Network Topology in Young Adult Women. Biol Psychiatry Cogn Neurosci Neuroimaging 2018:3(12):1003-1012.
73 Lampela P, Tolppanen A, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Taipale H. Asthma and Chronic Obstructive Pulmonary Disease as a Comorbidity and Association with the Choice of Antidementia Medication Among Persons with Alzheimer's Disease. J Alzheimers Dis 2020:73(3):1243-1251.
74 Räsänen N, Tiihonen J, Koskuvi M, Lehtonen S, Jalkanen N, Karmila N, Weert I, Vaurio O, Ojansuu I, Lähteenvuo M, Pietiläinen O, Koistinaho J. Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner. Biol Psychiatry Glob Open Sci 2024:4(4):100313.
75 Taipale H, Bergström J, Gèmes K, Tanskanen A, Ekselius L, Mittendorfer-Rutz E, Helgesson M. Attention-Deficit/Hyperactivity Disorder Medications and Work Disability and Mental Health Outcomes. JAMA Netw Open 2024:7(3):e242859.
76 Boccardi M, Bocchetta M, Aronen HJ, Repo-Tiihonen E, Vaurio O, Thompson PM, Tiihonen J, Frisoni GB. Atypical nucleus accumbens morphology in psychopathy: Another limbic piece in the puzzle. Int J Law Psychiatry 2013:36:157-167.
77 Vallius S, Taipale H, Koponen M, Tolppanen A, Tanskanen A, Hartikainen S, Tiihonen M. Automated multi-dose dispensing in persons with and without Alzheimer's disease-impacts on pharmacotherapy. Eur J Clin Pharmacol 2022:78(3):513-521.
78 Ojala KP, Tiihonen J, Repo-Tiihonen E, Tikkanen R, Virkkunen M. Basal insulin secretion, PCL-R and recidivism among impulsive violent alcoholic offenders. Psychiatry Res 2015:225(3):420-4.
79 Joensuu M, Ahola P, Knekt P, Lindfors O, Saarinen P, Tolmunen T, Valkonen-Korhonen M, Vanninen R, Jääskeläinen T, Virtala E, Kuikka J, Tiihonen J, Lehtonen J. Baseline symptom severity predicts serotonin transporter change during psychotherapy in patients with major depression. Psychiatry Clin Neurosci 2016:70(1):34-41.
80 Laukkanen E, Kuosmanen L, Louheranta O, Ryynänen O, Vehviläinen-Julkunen K. A Bayesian network model to identify the associations between the use of seclusion in psychiatric care and nursing managers' attitudes towards containment methods. J Psychiatr Mental Health Nurs 2021:28(5):815-828.
81 Taipale H, Särkilä H, Tanskanen A, Kurko T, Taiminen T, Tiihonen J, Sund R, Tuulio-henriksson A, Saastamoinen L, Hietala J:. Bentsodiatsepiinien käyttö pitkäaikaistuu yli kolmasosalla aloittajista. Duodecim 2021:137(1):103.
82 Kurko T, Saastamoinen L, Tuulio-Henriksson A, Taiminen T, Tiihonen J, Airaksinen M, Hietala J. Bentsodiatsepiinien pitkäaikaiskäyttö on vähentynyt. Suomen Lääkärilehti 2018:73(20):1292-1299.
83 Ermis C, Taipale H, Tiihonen J. Bipolar depression management needs randomised controlled trial evidence - Authors' reply. Lancet Psychiatry 2025:12(5):331-332.
84 Niskanen M, Kärkkäinen O, Taipale H, Lieslehto J, Tiihonen J, Hamina A. Bipolar disorder and poisoning due to medicines or illegal substances. Acta Psychiatr Scand 2025:152(4):299-307.
85 Nummenmaa L, Lukkarinen L, Sun L, Putkinen V, Seppälä K, Karjalainen T, Karlsson HK, Hudson M, Venetjoki N, Salomaa M, Rautio P, Hirvonen J, Lauerma H, Tiihonen J. Brain basis of psychopathy in criminal offenders and general population. Cereb Cortex 2021:31(9):4104-4114.
86 Noppari T, Sun L, Lukkarinen L, Putkinen V, Tani P, Lindberg N, Saure E, Lauerma H, Tiihonen J, Venetjoki N, Salomaa M, Rautio P, Hirvonen J, Salmi J, Nummenmaa L. Brain structural alterations in autism and criminal psychopathy. Neuroimage Clin 2022:35:103116.
87 Budhiraja M, Savic I, Lindner P, Jokinen J, Tiihonen J, Hodgins S. Brain structure abnormalities in young women who presented conduct disorder in childhood/adolescence. Cogn Affect Behav Neurosci 2017:17(4):869-885.
88 Correll CU, Emborg Mafi C, Fagiolini A, Seerden P, Seifritz E, Tiihonen J, Vita A, Citrome L. Brexpiprazole in the Management of Schizophrenia: A Consensus Report of Best Practices From Acute to Maintenance Treatment. Neuropsychiatr Dis Treat 2025:21:1857-1883.
89 Mittendorfer-Rutz E, Rahman S, Tanskanen A, Majak M, Mehtälä J, Hoti F, Jedenius E, Enkusson D, Leval A, Sermon J, Taipale H, Tiihonen J. Burden for Parents of Patients With Schizophrenia-A Nationwide Comparative Study of Parents of Offspring With Rheumatoid Arthritis, Multiple Sclerosis, Epilepsy, and Healthy Controls. Schizophr Bull 2019:45(4):794-803.
90 Solje E, Hartikainen P, Valori M, Vanninen R, Tiihonen J, Hakola P, Tienari PJ, Remes AM. The C9ORF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation. Neurobiol Aging 2014:35(7):1780e13-7.
91 Paljärvi T, Herttua K, Taipale H, Lähteenvuo M, Tanskanen A, Tiihonen J. Cardiovascular mortality in bipolar disorder: Population-based cohort study. Acta Psychiatr Scand 2024:150(2):56-64.
92 Tolppanen A, Taipale H, Koponen M, Tiihonen J, Hartikainen S. Causes of death in a nationwide cohort of community-dwellers with Alzheimer's disease. BMC Geriatr 2020:20(1):441.
93 Paljärvi T, Herttua K, Taipale H, Lähteenvuo M, Tanskanen A, Fazel S, Tiihonen J. Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study. BMJ Ment Health 2023:26(1):e300700.
94 Gustafsson TT, Pauly V, Hamina A, Zi?ba M, Kiejna A, Orleans V, Revsbech EAndersen, Valentin JBrink, Isayeva U, Manchia M, Tiihonen J, Mittendorfer-Rutz E, Nielsen RErnst, Boyer L, Taipale H, Taipale H. Cause-specific mortality due to physical illness in severe mental disorders in Europe: a population-based multi-country cohort study. PPPP 2026:11(8):e506-e517.
95 Ojansuu I, Ojansuu I, Putkonen H, Tiihonen J. Cause-specific mortality in Finnish forensic psychiatric patients. Nord J Psychiatry 2018:72(5):374-379.
96 Gustafsson TT, Taipale H, Lähteenvuo M, Tanskanen A, Svirskis T, Huoponen S, Tiihonen J. Cause-specific mortality in treatment-resistant major depression: Population-based cohort study. J Affect Disord 2025:1(368):136-142.
97 Toivonen P, Könönen M, Niskanen E, Vaurio O, Repo-Tiihonen E, Seppänen A, Aronen HJ, Vanninen R, Tiihonen J, Laakso M. Cavum septum pellucidum and psychopathy. Br J Psychiatry 2013(203):152-153.
98 Tiihonen J, Taipale H. The challenges of antipsychotic polypharmacy. Lancet Psychiatry 2024:11(12):945-946.
99 Kuosmanen A, Tiihonen J, Repo-Tiihonen E, Eronen M, Turunen H. Changes in patient safety culture: A patient safety intervention for Finnish forensic psychiatric hospital staff. J Nurs Manag 2019:27(4):848-857.
100 Kärkkäinen O, Kokla M, Lehtonen M, Auriola S, Martiskainen M, Tiihonen J, Karhunen PJ, Hanhineva K, Kok E. Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use. Addict Biol 2021:26(6):e13035.
101 Heikkinen N, Kärkkäinen O, Laukkanen E, Kekkonen V, Kaarre O, Kivimäki P, Könönen M, Velagapudi V, Nandania J, Lehto SM, Niskanen E, Vanninen R, Tolmunen T. Changes in the serum metabolite profile correlate with decreased brain gray matter volume in moderate-to-heavy drinking young adults. Alcohol 2019:75:89-97.
102 López-Rubio C, Koponen M, Lampela P, Taipale H, Tanskanen A, Bell JS, Tolppanen A, Hartikainen S. Changes in the use of diabetes drugs among community-dwelling people with Alzheimer's disease. BMC Geriatr 2021:21(1):701.
103 Basnet S, Onyeka IN, Tiihonen J, Föhr J, Kauhanen J. Characteristics of drug-abusing females with and without children seeking treatment in Helsinki, Finland. Scand J Public Health 2015:43(3):221-8.
104 Särkilä H, Taipale H, Tanskanen A, Kurko T, Taiminen T, Tiihonen J, Sund R, Saastamoinen L, Hietala J, Niemelä S. Characteristics of high-dose benzodiazepine use: nationwide cohort study on new benzodiazepine users with 5-year follow-up. BJPsych Open 2024:10(5):e158.
105 Jeyapalan J, Sassi P, Mittendorfer Rutz E, Tiihonen J, Taipale H, Niemelä S. Characteristics of incident substance-induced psychosis compared to first-episode psychotic disorders: A nationwide register-linkage study from Sweden. Schizophr Res 2024:264:526-533.
106 Lundberg J, Cars T, Lööv S-Å, Söderling J, Tiihonen J, Leval A, Gannedahl A, Björkholm C, Själin M, Hellner C. Clinical and societal burden of incident major depressive disorder: A population-wide cohort study in Stockholm. Acta Psychiatr Scand 2022:146(1):51-63.
107 Sommer IE, Tiihonen J, van Mourik A, Tanskanen A, Taipale H. The clinical course of schizophrenia in women and men-a nation-wide cohort study. NPJ Schizophr 2020:6(1):12.
108 Tiihonen J, Tanskanen A, Bell JS, Dawson JL, Kataja V, Taipale H. Clozapine and the risk of haematological malignancies - Authors' reply. Lancet Psychiatry 2022:9(7):539-540.
109 Leucht S, Tiihonen J. Clozapine, long-acting injectables (and polypharmacy?) superior in U.S. and international registries. Editorial. Am J Psychiatry 2021:178(10):888-889.
110 Tiihonen J, Leucht S. Clozapine resistance - Augmentation strategies. Eur Neuropsychopharmacology 2013:23:338.
111 Putkonen A, Kuivalainen S, Louheranta O, Repo-Tiihonen E, Ryynänen OP, Kautiainen H, Tiihonen J. Cluster-randomized controlled trial of reducing seclusion and restraint in secured care of men with schizophrenia. Psychiatr Serv 2013:64(9):850-855.
112 Laukkanen E. Coercive Measures in Finnish Psychiatric Inpatient Care: Special Emphasis on Psychiatric Nursing Managers' Attitudes. Doctoral dissertation. Kuopio: University of Eastern Finland, 2021. Publications of the University of Eastern Finland. Dissertations in Health Sciences 608. 110 p.
113 Onyeka IN, Beynon CM, Uosukainen H, Korhonen MJ, Ilomäki J, Bell JS, Paasolainen M, Tasa N, Tiihonen J, Kauhanen J. Coexisting social conditions and health problems among clients seeking treatment for illicit drug use in Finland: The HUUTI study. BMC Public Health 2013:13:380.
114 Hallikainen I, Koivisto AM, Paajanen T, Hiltunen A, Karppi P, Vanhanen M, Välimäki T, Herukka S-K, Soininen H, Hänninen T. Cognitive and neuropsychiatric symptom differences in early stages of Alzheimer's Disease: Kuopio ALSOVA Study. Dement Geriatr Cogn Disord 2012:2:209-218.
115 Kuokkanen R, Lappalainen R, Repo-Tiihonen E, Tiihonen J, Aho-Mustonen K. Cognitive insight, clinical insight, and reasoning in schizophrenia: a pilot study in a forensic setting. J Forensic Psychol Pract 2016:16(4):253-267.
116 Lähteenvuo M, Ahola-Olli A, Suokas K, Holm M, Misiewicz Z, Jukuri T, Männynsalo T, Wegelius A, Haaki W, Kajanne R, Kyttälä A, Tuulio-Henriksson A, Lahdensuo K, Häkkinen K, Hietala J, Paunio T, Niemi-Pynttäri J, Kieseppä T, ..., Tiihonen J, et al. Cohort profile: SUPER-Finland - the Finnish study for hereditary mechanisms of psychotic disorders. BMJ Open 2023:13(4):e070710.
117 Tolppanen A, Taipale H, Koponen M, Lavikainen P, Tanskanen A, Tiihonen J, Hartikainen S. Cohort profile: the Finnish Medication and Alzheimer's disease (MEDALZ) study. BMJ Open 2016:6(7):e012100.
118 Solmi M, Thompson T, Cortese S, Estradé A, Agorastos A, Radua J, Dragioti E, Vancampfort D, Thygesen LC, Aschauer H, Schlögelhofer M, Aschauer E, Schneeberger A, Huber CG, Hasler G, Conus P, Cuénod KQ, ..., Tiihonen J, et al. Collaborative outcomes study on health and functioning during infection times (COH-FIT): Insights on modifiable and non-modifiable risk and protective factors for wellbeing and mental health during the COVID-19 pandemic from multivariable and network anal. Eur Neuropsychopharmacology 2025:90:1-15.
119 Solmi M, Thompson T, Cortese S, Estrade A, Agorastos A, Radua J, Dragioti E, Vancampfort D, Thygesen L, ..., Tiihonen J, et al. Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT): global and risk-group stratified course of well-being and mental health during the COVID-19 pandemic in adolescents. J Am Acad Child Adolesc Psychiatry 2025:64(4):499-519.
120 Solmi M, Estradé A, Thompson T, Agorastos A, Radua J, ..., Tiihonen J, et al. The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic. J Affect Disord 2022:299:393-407.
121 Tiihonen J, Taipale H, Correll CU. Commentary on Robert Whitaker's viewpoint. Psychol Med 2020:50(16):2653-2654.
122 Kivimies K, Repo-Tiihonen E, Kautiainen H, Tiihonen J. Comorbid opioid use is undertreated among forensic patients with schizophrenia. Subst Abuse Treat Prev Policy 2018:13(1):39.
123 Taipale H, Mehtälä J, Tanskanen A, Tiihonen J. Comparative Effectiveness of Antipsychotic Drugs for Rehospitalization in Schizophrenia-A Nationwide Study With 20-Year Follow-up. Schizophr Bull 2018:44(6):1381-1387.
124 Taipale H, Tanskanen A, Howes O, Correll CU, Kane JM, Tiihonen J. Comparative effectiveness of antipsychotic treatment strategies for relapse prevention in first-episode schizophrenia in Finland: a population-based cohort study. Lancet Psychiatry 2025:12(2):122-130.
125 Taipale H, Lähteenvuo M, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J. Comparative Effectiveness of Antipsychotics for Risk of Attempted or Completed Suicide Among Persons With Schizophrenia. Schizophr Bull 2021:47(1):23-30.
126 Hamina A, Taipale H, Lieslehto J, Lähteenvuo M, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J. Comparative Effectiveness of Antipsychotics in Patients With Schizophrenia Spectrum Disorder. JAMA Netw Open 2024:7(10):e2438358.
127 Holm M, Tanskanen A, Lähteenvuo M, Tiihonen J, Taipale H. Comparative effectiveness of mood stabilizers and antipsychotics in the prevention of hospitalization after lithium discontinuation in bipolar disorder. Eur Neuropsychopharmacology 2022:61:36-42.
128 Lieslehto J, Tiihonen J, Lähteenvuo M, Mittendorfer-Rutz E, Tanskanen A, Taipale H. Comparative Effectiveness of Pharmacotherapies for the Risk of Attempted or Completed Suicide Among Persons With Borderline Personality Disorder. JAMA Netw Open 2023:6(6):e2317130.
129 Forsman J, Taipale H, Masterman T, Tiihonen J, Tanskanen A. Comparison of dispensed medications and forensic-toxicological findings to assess pharmacotherapy in the Swedish population 2006 to 2013. Pharmacoepidemiol Drug Saf 2018:27(10):1112-1122.
130 Cullen AE, de Montgomery CJ, Norredam M, Bergström J, Krasnik A, Taipale H, Mittendorfer-Rutz E. Comparison of Hospitalization for Nonaffective Psychotic Disorders Among Refugee, Migrant, and Native-Born Adults in Sweden and Denmark. JAMA Netw Open 2023:6(10):e2336848.
131 Tolppanen A, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S. Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer's disease - exposure-matched cohort study. BMC Geriatr 2016:16(1):204.
132 Moga DC, Taipale H, Tolppanen A-M, Tanskanen A, Tiihonen J, Hartikainen S, Wu Q, Jicha GA, Gnjidic D. A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland. Drugs Aging 2017:34(1):55-65.
133 van der Horst MZ, Meijer Y, de Boer N, Guloksuz S, Hasan A, Siskind D, Wagner E, ..., Hallikainen T, et al. Comprehensive dissection of prevalence rates, sex differences, and blood level-dependencies of clozapine-associated adverse drug reactions. Psychiatry Res 2023:330:115539.
134 Torvinen-Kiiskinen S, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S. Concomitant use of acetylcholine esterase inhibitors and urinary antispasmodics among Finnish community-dwelling persons with Alzheimer disease. J Clin Psychopharmacol 2014:34(6):722-7.
135 Karttunen N, Taipale H, Hamina A, Tanskanen A, Tiihonen J, Tolppanen A, Hartikainen S. Concomitant use of benzodiazepines and opioids in community-dwelling older people with or without Alzheimer's disease-A nationwide register-based study in Finland. Int J Geriatr Psychiatry 2019:34(2):280-288.
136 Ahola P, Härkänen T, Lehtonen J, Lindfors O, Knekt P, Joensuu M, Saarinen P, Tolmunen T, Virtala E, Tiihonen J, Valkonen-Korhonen M. Concordance and discordance in how patients and therapists experience the psychotherapy process in the treatment of depression. Psychiatr Fenn 2020:51:122-141.
137 Lindner P, Savic I, Sitnikov R, Budhiraja M, Liu Y, Jokinen J, Tiihonen J, Hodgins S. Conduct disorder in females is associated with reduced corpus callosum structural integrity independent of comorbid disorders and exposure to maltreatment. Transl Psychiatry 2016:6:e714.
138 Lehti V, Taipale H, Gissler M, Tanskanen A, Elonheimo M, Tiihonen J, Suvisaari J. Continuity of antipsychotic medication use among migrant and Finnish-born populations with a psychotic disorder: a register-based study. Psychol Med 2023:53(3):833-843.
139 Tiihonen J, Tanskanen A, Solmi M, Rubio JM, Correll CU, Kane JM, Taipale H. Continuous Dopamine D2 Receptor Blockade and Long-Term Outcome in First-Episode Schizophrenia. Am J Psychiatry 2025:182(4):341-348.
140 Koskuvi M, Lehtonen S, Trontti K, Keuters M, Wu Y, Koivisto H, Ludwig A, Plotnikova L, Virtanen PL, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, ..., Lähteenvuo M, ..., Tiihonen J, et al. Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia. Glia 2022:70(4):650-660.
141 Konttajärvi T, Haapea M, Huhtaniska S, Björnholm L, Miettunen J, Isohanni M, Penttilä M, Murray GK, Koponen H, Vernon AC, Jääskeläinen E, Lieslehto J. The contribution of first-episode illness characteristics and cumulative antipsychotic usage to progressive structural brain changes over a long-term follow-up in schizophrenia. Psychiatry Res 2024:339:111790.
142 Tiihonen J, Koskuvi M, Lähteenvuo M, Virtanen PL, Ojansuu I, Vaurio O, Gao Y, Hyötyläinen I, Puttonen KA, Repo-Tiihonen E, Paunio T, Rautiainen M, Tyni S, Koistinaho J, Lehtonen S. Correction: Neurobiological roots of psychopathy. Mol Psychiatry 2020:25(12):3455-3456.
143 Hodgins S, Eronen M, Freese R, Hart S, Mueller-Isberner R, Ross D, Webster C, Tiihonen J. Correspondence regarding De Girolamo et al., 2021 'A multinational case-control study comparing forensic and non-forensic patients with schizophrenia spectrum disorders: the EU-VIORMED project'. Psychol Med 2023:53(8):3764-3765.
144 Budhiraja M, Pereira JB, Lindner P, Westman E, Jokinen J, Savic I, Tiihonen J, Hodgins S. Cortical structure abnormalities in females with conduct disorder prior to age 15. Psychiatry Res Neuroimaging 2019:289:37-44.
145 Juntunen A, Määttä S, Könönen M, Kallioniemi E, Niskanen E, Kaarre O, Kivimäki P, Vanninen R, Tolmunen T, Ferreri F, Kekkonen V. Cortical thickness is inversely associated with transcranial magnetic stimulation-evoked N45 potential among young adults whose heavy drinking began in adolescence. Alcohol Clin Exp Res (Hoboken) 2023:47(7):1341-1351.
146 Lähteenvuo M, Taipale H, Tanskanen A, Rannanpää S, Tiihonen J. Courses of treatment and risk factors for treatment-resistant depression in Finnish primary and special healthcare: A nationwide cohort study. J Affect Disord 2022:308:236-242.
147 Soppela H, Aaltonen M, Aho K, Heikkinen S, Kivisild A, Lehtonen A, Leppänen L, Mäki-Petäjä-Leinonen A, Rinnankoski I, Tervonen L, Tiihonen J, Lähteenvuo M, Haapasalo A, Portaankorva AM, Hartikainen P, Katisko K, Krüger J, Solje E. Criminal Behavior in Early Onset Neurodegenerative Diseases. Eur J Neurol 2025:32(4):e70134.
148 Rahkonen A, Taipale H, Koponen M, Hartikainen S, Tolppanen A, Tanskanen A, Tiihonen M. The Cumulative Use of Muscle Relaxants and the Risk of Alzheimer's Disease: A Nationwide Case-Control Study. J Alzheimers Dis 2023:91(4):1283-1290.
149 Ompad G, Cesta CE, Cohen J, Leinonen M, Taipale H, Li H, et al. Current Use of Common Data Models in the Nordic Countries. Pharmacoepidemiol Drug Saf 2025:34(11):e70242.
150 Ojansuu I, Tiihonen J, Lähteenvuo M. Deaths by suicide during inpatient treatment among Finnish forensic psychiatric patients. Psychiatr Fenn 2025:56:234-239.
151 Laukkanen V, Storvik M, Häkkinen M, Akamine Y, Tupala E, Virkkunen M, Tiihonen J. Decreased GABA(A) benzodiazepine binding site densities in postmortem brains of Cloninger type 1 and 2 alcoholics. Alcohol 2013:47:103-108.
152 Laukkanen V, Laukkanen V, Kärkkäinen O, Kautiainen H, Tiihonen J, Storvik M. Decreased [³H]naloxone Binding in the Dentate Gyrus of Cloninger Type 1 Anxiety-Prone Alcoholics: A Postmortem Whole-Hemisphere Autoradiography Study. Alcohol Clin Exp Res 2015:39(8):1352-9.
153 Kuivalainen S, Vehviläinen-Julkunen K, Louheranta O, Putkonen A, Repo-Tiihonen E, Tiihonen J. De-escalation techniques used, and reasons for seclusion and restraint, in a forensic psychiatric hospital. Int J Ment Health Nurs 2017:26(5):513-524.
154 Suokas JT, Suvisaari JM, Haukka J, Korhonen P, Tiihonen J. Description of long-term polypharmacy among schizophrenia outpatiens. Soc Psychiatry Psychiatr Epidemiol 2013:48:631-638.
155 Braithwaite B, Paananen J, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. Detection of medications associated with Alzheimer's disease using ensemble methods and cooperative game theory. Int J Med Inf 2020:141:104142.
156 Olubamwo OO, Onyeka IN, Aregbesola A, Ronkainen K, Tiihonen J, Föhr J, Kauhanen J. Determinants of hospitalizations for pneumonia among Finnish drug users. SAGE Open Med 2018:6:2050312118784311.
157 van der Horst MZ, de Boer N, ..., Tuppurainen H, ..., Lähteenvuo M, ..., Hallikainen T, et al. Determinants of patient satisfaction in clozapine users: results from the Clozapine International Consortium (CLOZIN). Schizophrenia (Heidelb) 2025:11(1):28.
158 Lieslehto J, Tiihonen J, Lähteenvuo M, Leucht S, Correll CU, Mittendorfer-Rutz E, Tanskanen A, Taipale H. Development and Validation of a Machine Learning-Based Model of Mortality Risk in First-Episode Psychosis. JAMA Netw Open 2024:7(3):e240640.
159 Aregbesola A, Onyeka IN, Olubamwo O, Ronkainen K, Tiihonen J, Föhr J, Kauhanen J. Diabetes hospitalizations and deaths in a cohort of treatment-seeking illicit drug users. SAGE Open Med 2018:6:2050312118768164.
160 Laakso MP, Jukarainen NM, Vepsäläinen J. Diagnosis of dementias by high-field 1H MRS of cerebrospinal fluid. J Neurol Neurosurg Psychiatry 2015:86(12):1286-90.
161 Hamina A, Taipale H, Tanskanen A, Tolppanen A-M, Tiihonen J, Hartikainen S. Differences in analgesic use in community-dwelling persons with and without Alzheimer's disease. Eur J Pain 2017:21(4):658-667.
162 Ahti J, Kieseppä T, Suvisaari J, Suokas K, Holm M, Wegelius A, Ahola-Olli A, Häkkinen K, Kampman O, Lähteenvuo M, Paunio T, Tiihonen J, Tuulio-Henriksson A, Isometsä E. Differences in psychosocial functioning between psychotic disorders in the Finnish SUPER study. Schizophr Res 2022:244:10-17.
163 Vinkers CH, Kupka RW, Penninx BW, Ruhé HG, van Gaalen JM, van Haaren PC, Schellekens AF, Jauhar S, Ramos-Quiroga JA, Vieta E, Tiihonen J, Veldman SE, Veling W, Vis R, de Wit LE, Luykx JJ. Discontinuation of psychotropic medication: a synthesis of evidence across medication classes. Mol Psychiatry 2024:29(8):2575-2586.
164 Bramness JG, Hjorthoj C, Niemelä S, Taipale H, Rognil EB. Discussing the concept of substance-induced psychosis (SIP). Psychol Med 2024:54(11):2852-2856.
165 Wagner E, Højlund M, Fiedorowicz JG, Nielsen RE, Østergaard SD, Høye A, Heiberg IH, Poddighe L, Delogu M, Holt RI, Correll CU, Cortese S, Carvalho AF, Boyer L, Dragioti E, Du Rietz E, Firth J, Fusar-Poli P, Hartman CA, ..., Taipale H, et al. Disparities in diabetes treatment and monitoring for people with and without mental disorders: a systematic review and meta-analysis. Lancet Psychiatry 2026:13(2):112-124.
166 Hakala A, Tolppanen A, Koponen M, Taipale H, Tanskanen A, Hartikainen S, Tiihonen M. Does Recent Hospitalization Increase Antipsychotic Initiation Among Community Dwellers With Alzheimer's Disease? J Am Med Dir Assoc 2021:22(7):1543-1547.e3.
167 Luykx JJ, Tanskanen A, Lähteenvuo M, Manu P, Correll CU, Hasan A, Lieslehto J, Taipale H, Tiihonen J. Dopamine D2 receptor antagonism of antipsychotics and the risk of death due to choking. Psychiatry Res 2024:339:116012.
168 Lintunen J, Hamina A, Lähteenvuo M, Paljärvi T, Tanskanen A, Tiihonen J, Taipale H. Dosing levels of antipsychotics and mood stabilizers in bipolar disorder: A Nationwide cohort study on relapse risk and treatment safety. Acta Psychiatr Scand 2025:151(1):81-91.
169 Tanskanen A, Taipale H, Koponen M, Tolppanen AM, Hartikainen S, Ahonen R, Tiihonen J. Drug exposure in register-based research-An expert-opinion based evaluation of methods. PLoS ONE 2017:12(9):e0184070.
170 Lintunen J. Drug Repurposing in Severe Mental Disorders. Findings from Nationwide Register-Based Studies. Doctoral dissertation. Kuopio: University of Eastern Finland, 2022. Publications of the University of Eastern Finland. Dissertations in Health Sciences 695. 138 p.
171 Taipale H, Koponen M, Tanskanen A, Tolppanen AM, Tiihonen J, Hartikainen S. Drug use in persons with and without Alzheimer's disease aged 90 years or more. Age Ageing 2016:45(6):900-904.
172 Tanskanen A. Drug Use Modelling Method PRE2DUP. From Prescriptions to Drug Use Periods. Doctoral dissertation. Kuopio: University of Eastern Finland, 2019. Publications of the University of Eastern Finland. Dissertations in Health Sciences 514. 59 p.
173 Hamina A, Skurtveit S, Hoffmann M. Drugs utilization research in specific therapeutic areas-opioids. In: Elseviers M, Wettermark B, Benkö R et al, eds. Drug Utilization Research: Methods and Applications, 2nd edition. Wiley, 2024.
174 Kettunen R, Taipale H, Tolppanen A, Tanskanen A, Tiihonen J, Hartikainen S, Koponen M. Duration of new antidepressant use and factors associated with discontinuation among community-dwelling persons with Alzheimer's disease. Eur J Clin Pharmacol 2019:75(3):417-425.
175 Saarinen A, Keltikangas-Järvinen L, Jääskeläinen E, Huhtaniska S, Pudas J, Tovar-Perdomo S, Penttilä M, Miettunen J, Lieslehto J. Early Adversity and Emotion Processing From Faces: A Meta-analysis on Behavioral and Neurophysiological Responses. Biol Psychiatry Cogn Neurosci Neuroimaging 2021:6(7):692-705.
176 Torvinen-Kiiskinen S, Tolppanen A-M, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Taipale H. Editorial: let's take a break from studying the PPI-fracture association-Authors' reply. Editorial. Aliment Pharmacol Ther 2018:47(11):1544-1545.
177 Lampela P, Tanskanen A, Lähteenvuo M, Tiihonen J, Taipale H. Effect of severity of depression on augmentation of antidepressant medication in young adults with depression. Acta Psychiatr Scand 2024:149(1):41-51.
178 Solmi M, Taipale H, Holm M, Tanskanen A, Mittendorfer-Rutz E, Correll CU, Tiihonen J. Effectiveness of Antipsychotic Use for Reducing Risk of Work Disability: Results From a Within-Subject Analysis of a Swedish National Cohort of 21,551 Patients With First-Episode Nonaffective Psychosis. Am J Psychiatry 2022:179(12):938-946.
179 Tiihonen J, Tanskanen A, Mittendorfer-Rutz E, Howes OD, Correll CU, Siskind D, Taipale H. Effectiveness of clozapine augmentation with specific doses of other antipsychotics in schizophrenia: a meta-analysis from two nationwide cohorts. World Psychiatry 2025:24(2):250-259.
180 Wagner E, Katyal S, Lee IO, Tasnim S, El Wadia H, Mortazavi M, García-Carmona JA, Hasan A, Colman I, Taipale H, Tiihonen J, Correll CU, Højlund M, Solmi M. Effectiveness of Long-Acting Injectable Antipsychotics Versus Oral Antipsychotics in People With Bipolar Disorder: A Systematic Review and Meta-Analysis of Observational Studies. Efficacité des antipsychotiques injectables à action prolongée par rapport aux antipsychotiques oraux chez les personnes atteintes de troubles bipolaires : revue systématique et méta-analyse d'études observationnelles. Can J Psychiatry 2026:71(6):420-435.
181 Lähteenvuo M, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J. Effectiveness of pharmacotherapies for delusional disorder in a Swedish national cohort of 9076 patients. Schizophr Res 2021:228:367-372.
182 Tikkanen R, Saukkonen T, Fex M, Bennet H, Rautiainen MR, Paunio T, Koskinen M, Panarsky R, Bevilacqua L, Sjöberg RL, Tiihonen J, Virkkunen M. The effects of a HTR2B stop codon and testosterone on energy metabolism and beta cell function among antisocial Finnish males. J Psychiatric Res 2016:81:79-86.
183 Solmi M, Croatto G, Gupta A, Fabiano N, Wong S, Fornaro M, Schneider LK, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J, Cortese S, Dragioti E, Rietz ED, Nielsen RE, Firth J, Fusar-Poli P, et al. Effects of antipsychotic treatment on cardio-cerebrovascular related mortality in schizophrenia: A subanalysis of a systematic review and meta-analysis with meta-regression of moderators. Eur Neuropsychopharmacology 2024:88:6-20.
184 Shen Q, Heikkinen N, Kärkkäinen O, Gröhn H, Könönen M, Liu Y, Kaarre O, Zhang Z, Tan C, Tolmunen T, Vanninen R. Effects of long-term adolescent alcohol consumption on white matter integrity and their correlations with metabolic alterations. Psychiatry Res Neuroimaging 2019:294:111003.
185 Ahola P, Joensuu M, Knekt P, Lindfors O, Saarinen P, Tolmunen T, Valkonen-Korhonen M, Jääskeläinen T, Virtala E, Tiihonen J, Lehtonen J. Effects of Scheduled Waiting for Psychotherapy in Patients With Major Depression. J Nerv Ment Dis 2017:205(8):611-617.
186 Taipale M, Tiihonen J, Korhonen J, Popovic D, Vaurio O, Lähteenvuo M, Lieslehto J. Effects of Substance Use and Antisocial Personality on Neuroimaging-Based Machine Learning Prediction of Schizophrenia. Schizophr Bull 2023:49(6):1568-1578.
187 Efthimiou O, Taipale H, Radua J, Schneider-Thoma J, Pinzón-Espinosa J, Ortuño M, Vinkers CH, Mittendorfer-Rutz E, Cardoner N, Tanskanen A, Fusar-Poli P, Cipriani A, Vieta E, Leucht S, Tiihonen J, Luykx JJ. Efficacy and effectiveness of antipsychotics in schizophrenia: network meta-analyses combining evidence from randomised controlled trials and real-world data. Lancet Psychiatry 2024:11(2):102-111.
188 Lochmann van Bennekom M, IntHout J, Gijsman HJ, Akdede BB, Yagcioglu AE, Barnes TR, Galling B, ..., Repo-Tiihonen E, et al. Efficacy and tolerability of antipsychotic polypharmacy for schizophrenia spectrum disorders. A systematic review and meta-analysis of individual patient data. Schizophr Res 2024:272:1-11.
189 Holopainen R, Tiihonen J, Lähteenvuo M. Efficacy of immersive extended reality (XR) interventions on different symptom domains of schizophrenia spectrum disorders. A systematic review. Front Psychiatry 2023:14:1208287.
190 Stenius J, Heinonen E, Lindfors J, Holma J, Knekt P. Ego Impairment Index (EII-2) as a predictor of outcome in short- and long-term psychotherapy during a 5-year follow-up. J Clin Psychol 2022:78(9):1739-1751.
191 Holm M, Taipale H, Tanskanen A, Tiihonen J, Mitterdorfer-Rutz E. Employment among people with schizophrenia or bipolar disorder: A population-based study using nationwide registers. Acta Physiol Scand 2021:143(1):61-71.
192 Kärkkäinen OK, Lehtonen M, Laukkanen V, Tupala E, Hyytiä P, Kautiainen H, Tiihonen J, Callaway JC, Storvik M. Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics. Alcohol 2013:47:399-403.
193 Tiihonen E. Epäsosiaalinen persoonallisuushäiriö. Lääkärin käsikirja - viimeisin muutos 12.4.2013.
194 Repo-Tiihonen E, Hallikainen T. Epäsosiaalinen persoonallisuushäiriö. Duodecim 2016:132(2):130-6.
195 Tiwari AK, Need AC, Lohoff FW, Zai CC, Chowdhury NI, Müller DJ, Putkonen A, Repo-Tiihonen E, Hallikainen T, Yagcioglu AE, Tiihonen J, Kennedy JL, Meltzer HY. Exome sequence analysis of Finnish patients with clozapine-induced agranulocytosis. Mol Psychiatry 2014:19(4):403-5.
196 Weizmann-Henelius G, Putkonen H, Rissanen T, Eronen M, Webster CD. Exploring a new structured professional judgment measure (impulsivity measure related to violence) after an average follow-up of 10 years: A study of Finnish offenders. Crim Behav Ment Health 2019:29(1):57-68.
197 Pauli M, Ölund Alonso H, Liljeberg J, Gustavsson P, Tiihonen J, Howner K. Exploring the relation between high-activity COMT Val158Met genotype and psychopathy in male offenders. J Forensic Psychiatry Psychol 2022:33(1):172-177.
198 Miles SW, Sheridan J, Russell B, Kydd R, Wheeler A, Walters C, Gamble G, Hardley P, Jensen M, Kuoppasalmi K, Tuomola P, Föhr J, Kuikanmäki O, Vorma H, Salokangas R, Mikkonen A, Kallio M, Kauhanen J, Kiviniemi V, Tiihonen J. Extended-release methylphenidate for treatment of amphetamine/methamphetamine dependence: a randomized, double-blind, placebo-controlled trial. Addiction 2013:108(7):1279-1286.
199 Kekkonen V, Kraav S-L, Hintikka J, Kivimäki P, Kaarre O, Tolmunen T. Externally oriented thinking style increases primary health care use in adolescence. Eur J Public Health 2023:33(3):418-423.
200 Askola R, Louheranta O, Seppänen A. Factors Affecting Treatment Regress and Progress in Forensic Psychiatry: A Thematic Analysis. Front Psychiatry 2022:13:884410.
201 Correll CU, Bitter I, Hoti F, Mehtälä J, Wooller A, Pungor K, Tiihonen J. Factors and their weight in reducing life expectancy in schizophrenia. Schizophr Res 2022:250:67-75.
202 Uosukainen H, Ilomäki J, Kauhanen J, Tacke U, Föhr J, Tiihonen J, Bell JS. Factors associated with buprenorphine compared to amphetamine abuse among clients seeking treatment in Finland. J Subst Abuse Treat 2014:46(5):561-566.
203 Onyeka IN, Olubamwo O, Beynon CM, Ronkainen K, Förh J, Tiihonen J, Tuomola P, Tasa N, Kauhanen J. Factors Associated with Hospitalization for Blood-Borne Viral Infections Among Treatment-Seeking Illicit Drug Users. J Subst Abuse Treat 2015:53:71-77.
204 Hamina A, Odsbu I, Hjellvik V, Lid TG, Clausen T, Skurtveit S. Fatal drug overdoses in individuals treated pharmacologically for chronic pain: a nationwide register-based study. Br J Anaesth 2024:132(1):86-95.
205 Kuokkanen R. The feasibility and acceptability of metacognitive therapy in a forensic setting: a case report of chronic paranoid schizophrenia with persistent depressive symptoms. Psychiatry Research Case Reports 2025:4(2):100282.
206 Vaurio O, Lähteenvuo M, Kautiainen H, Repo-Tiihonen E, Tiihonen J. Female Psychopathy and Mortality. Front Psychiatry 2022:13:831410.
207 Thomson A, Tiihonen J, Miettunen J, Virkkunen M, Lindberg N. Firesetting and general criminal recidivism among a consecutive sample of Finnish pretrial male firesetters: A register-based follow-up study. Psychiatry Res 2018:259:377-384.
208 Thomson A, Tiihonen J, Miettunen J, Virkkunen M, Lindberg N. Fire-setting performed in adolescence or early adulthood predicts schizophrenia: a register-based follow-up study of pre-trial offenders. Nord J Psychiatry 2017:71(2):96-101.
209 Lumén K, Louheranta O, Kuosmanen L. Forensic Psychiatric Patients' Experiences of Personal Recovery: A Wilsonian Concept Analysis. J Forensic Nurs 2024:20(2):103-112.
210 Askola R, Nikkonen M, Paavilainen E, Soininen P, Putkonen H, Louheranta O. Forensic Psychiatric Patients' Perspectives on Their Care: A Narrative View. Perspect Psychiatr Care 2018:54(1):64-73.
211 Seppänen A, Joelsson P, Ahlgren-Rimpiläinen A, Repo-Tiihonen E. Forensic psychiatry in Finland: an overview of past, present and future. Int J Ment Health Syst 2020:14:29.
212 Tanskanen A, Taipale H, Koponen M, Tolppanen AM, Hartikainen S, Ahonen R, Tiihonen J. From prescription drug purchases to drug use periods - a second generation method (PRE2DUP). BMC Med Inform Decis Mak 2015:15:21.
213 Tanskanen A1, Taipale H, Koponen M, Tolppanen AM, Hartikainen S, Ahonen R, Tiihonen J. From prescriptions to drug use periods - things to notice. BMC Res Notes 2014:7:796.
214 Häkkinen K, Kiander W, Kidron H, Lähteenvuo M, Urpa L, Lintunen J, Vellonen K, Auriola S, Holm M, Lahdensuo K, Kampman O, Isometsä E, Kieseppä T, Lönnqvist J, Suvisaari J, Hietala J, Tiihonen J, Palotie A, Ahola-Olli AV, Niemi M. Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder. Mol Pharm 2023:20(3):1500-1508.
215 Ojansuu I, Latvala A, Kautiainen H, Forsman J, Tiihonen J, Lähteenvuo M. General and violent recidivism of former forensic psychiatric patients in Finland. Front Psychiatry 2023:14:1157171.
216 Ahti J, Kieseppä T, Haaki W, Suvisaari J, Niemelä S, Suokas K, Holm M, Wegelius A, Kampman O, Lähteenvuo M, Paunio T, Tiihonen J, Hietala J, Isometsä E. General medical comorbidities in psychotic disorders in the Finnish SUPER study. Schizophrenia (Heidelb) 2024:10(1):124.
217 Tiihonen J, Rautiainen MR, Ollila HM, Repo-Tiihonen E, Virkkunen M, Palotie A, Pietiläinen O, Kristiansson K, Joukamaa M, Lauerma H, Saarela J, Tyni S, Vartiainen H, Paananen J, Goldman D, Paunio T. Genetic background of extreme violent behavior. Mol Psychiatry 2015:20(6):786-92.
218 Kämpe A, Suvisaari J, Lähteenvuo M, Singh T, Ahola-Olli A, Urpa L, Haaki W, Hietala J, Isometsä E, Jukuri T, Kampman O, Kieseppä T, Lahdensuo K, Lönnqvist J, Männynsalo T, Paunio T, Niemi-Pynttäri J, Suokas K, Tuulio-Henriksson A, Veijola J, et al. Genetic contribution to disease-course severity and progression in the SUPER-Finland study, a cohort of 10,403 individuals with psychotic disorders. Mol Psychiatry 2024:29(9):2733-2741.
219 Koskuvi M, Pörsti E, Hewitt T, Räsänen N, Wu Y, Trontti K, McQuade A, Kalyanaraman S, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Blurton-Jones M, Hovatta I, Lähteenvuo M, ..., Tiihonen J, et al. Genetic contribution to microglial activation in schizophrenia. Mol Psychiatry 2024:29(9):2622-2633.
220 Okhuijsen-Pfeifer C, van der Horst MZ, Bousman CA, Lin B, van Eijk KR, Ripke S, Ayhan Y, Babaoglu MO, Bak M, Alink W, van Beek H, Beld E, Bouhuis A, ..., Hallikainen T, Lähteenvuo M, Repo-Tiihonen E, Tuppurainen H, Tiihonen J, et al. Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders. Transl Psychiatry 2022:12(1):145.
221 Tielbeek JJ, Johansson A, Polderman TJ, Rautiainen MR, Jansen P, Taylor M, Tong X, Lu Q, Burt AS, ..., Paunio T, Tiihonen J, ..., Posthuma D. Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior. JAMA Psychiatry 2017:74(12):1242-1250.
222 Rautiainen MR, Paunio T, Repo-Tiihonen E, Virkkunen M, Ollila HM, Sulkava S, Jolanki O, Palotie A, Tiihonen J. Genome-wide association study of antisocial personality disorder. Transl Psychiatry 2016:6(9):e883.
223 Solmi M, Thompson T, Estradé A, Agorastos A, Radua J, Cortese S, Dragioti E, Vancampfort D, Thygesen LC, Aschauer H, Schlögelhofer M, Aschauer E, Schneeberger A, Huber CG, Hasler G, Conus P, Cuénod KQ, von Känel R, Tiihonen J, et al. Global and risk-group stratified well-being and mental health during the COVID-19 pandemic in adults: Results from the international COH-FIT Study. Psychiatry Res 2024:342:115972.
224 Sabe M, Pillinger T, Kaiser S, Chen C, Taipale H, Tanskanen A, Tiihonen J, Leucht S, Correll CU, Solmi M. Half a century of research on antipsychotics and schizophrenia: A scientometric study of hotspots, nodes, bursts, and trends. Neurosci Biobehav Rev 2022:136:104608.
225 Tolppanen A-M, Taipale H, Hartikainen S. Head or brain injuries and Alzheimer's disease: A nested case-control register study. Alzheimers Dement 2017:13(12):1371-1379.
226 Taipale H, Rahman S, Tanskanen A, Mehtälä J, Hoti F, Jedenius E, Enkusson D, Leval A, Sermon J, Tiihonen J, Mittendorfer-Rutz E. Health and work disability outcomes in parents of patients with schizophrenia associated with antipsychotic exposure by the offspring. Sci Rep 2020:10(1):1219.
227 Di Thiene D, Rahman S, Helgesson M, Wang M, Alexanderson K, Tiihonen J, La Torre G, Mittendorfer-Rutz E. Healthcare use among immigrants and natives in Sweden on disability pension, before and after changes of regulations. Eur J Public Health 2018:28(3):445-451.
228 Taipale H, Lähteenvuo M, Tanskanen A, Huoponen S, Rannanpää S, Tiihonen J. Healthcare utilization, costs, and productivity losses in treatment-resistant depression in Finland - a matched cohort study. BMC Psychiatry 2022:22(1):484.
229 Kekkonen V, Kallioniemi E, Kaarre O, Könönen M, Kivimäki P, Gröhn H, Tolmunen T, Vanninen R. Heavy drinking from adolescence to young adulthood is associated with an altered cerebellum. Alcohol 2021:92:35-40.
230 Louheranta O, Lähteenvuo M, Lähteenvuo M, Kangasniemi M. Henkinen ja hengellinen tuki terveydenhuollossa kenen vastuulla? . Sosiaalilääketieteellinen aikakauslehti 2016:53(4):234-241.
231 Partanen JJ, Häppölä P, Kämpe A, Ahola-Olli A, Hellsten A, Rask SM, Haaki W, Hietala J, Kampman O, Tiihonen J, Tanskanen AJ, Daly MJ, Ripatti S, Palotie A, Taipale H, Lähteenvuo M, Koskela JT. High Burden of Ileus and Pneumonia in Clozapine-Treated Individuals With Schizophrenia: A Finnish 25-Year Follow-Up Register Study. Am J Psychiatry 2024:181(10):879-892.
232 Taipale H, Koponen M, Tanskanen A, Tolppanen AM, Tiihonen J, Hartikainen S. High prevalence of psychotropic drug use among persons with and without Alzheimer's disease in Finnish nationwide cohort. Eur Neuropsychopharmacology 2014:24(11):1729-37.
233 Pisa F, Reinold J, Lavikainen P, Koponen M, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. Hip Fracture Risk in Antiepileptic Drug Initiators and Non-Initiators with Alzheimer's Disease. Clin Epidemiol 2021:13:295-307.
234 Konte B, Walters JT, Rujescu D, Legge SE, Pardiñas AF, Cohen D, Pirmohamed M, Tiihonen J, Hartmann AM, Bogers JP, van der Weide J, van der Weide K, Putkonen A, Repo-Tiihonen E, Hallikainen T, Silva E, Ingimarsson O, Sigurdsson E, et al. HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry. Transl Psychiatry 2021:11(1):214.
235 Halstead S, Yap CX, Warren N, Agarwal SM, Brand BA, Chan SKit, Cipriani A, Correll CU, Crossley N, D'Ambrosio E, Emsley R, Firth J, Gaughran F, Gee S, Hahn M, ..., Taipale H, Taylor D, Tiihonen J, et al. Holistic prevention and management of physical health side-effects of psychotropic medication: second report of the Lancet Psychiatry Physical Health Commission. Lancet Psychiatry 2025:12(9):673-699.
236 Taipale H, Purhonen M, Tolppanen AM, Tanskanen A, Tiihonen J, Hartikainen S. Hospital care and drug costs from five years before until two years after the diagnosis of Alzheimer's disease in a Finnish nationwide cohort. Scand J Public Health 2016:44(2):150-8.
237 Järvinen H, Taipale H, Koponen M, Tanskanen A, Tiihonen J, Tolppanen A-M, Hartikainen S. Hospitalization after oral antibiotic initiation in Finnish community dwellers with and without Alzheimer's disease: retrospective register-based cohort study. J Alzheimers Dis 2018:64(2):437-445.
238 Järvinen H, Taipale H, Koponen M, Tanskanen A, Tiihonen J, Tolppanen A-M, Hartikainen S. Hospitalization after Oral Antibiotic Initiation in Finnish Community Dwellers with and without Alzheimer's Disease: Retrospective Register-Based Cohort Study. J Alzheimers Dis 2018:64(2):437-445.
239 Onyeka IN, Beynon CM, Ronkainen K, Tiihonen J, Föhr J, Kuikanmäki O, Paasolainen M, Kauhanen J. Hospitalization in a cohort seeking treatment for illicit drug use in Finland. J Subst Abuse Treat 2015:53:64-70.
240 Tapiainen V, Hartikainen S, Taipale H, Tiihonen J, Tolppanen A-M. Hospital-treated mental and behavioral disorders and risk of Alzheimer's disease: A nationwide nested case-control study. Eur Psychiatry 2017:43:92-98.
241 Hamina A, Taipale H, Karttunen N, Tanskanen A, Tiihonen J, Tolppanen A, Hartikainen S. Hospital-Treated Pneumonia Associated with Opioid Use Among Community Dwellers with Alzheimer's Disease. J Alzheimers Dis 2019:69(3):807-816.
242 Thomson A, Tiihonen J, Miettunen J, Virkkunen M, Lindberg N, Tiihonen J. Hospital-treated suicide attempts among Finnish fire setters: a follow-up study. Crim Behav Ment Health 2016:26(5):395-402.
243 Gkogka A, Malwade S, Koskuvi M, Ohtonen S, Molnar E, Bose R, Ceccatelli S, Koistinaho J, Tiihonen J, Schalling M, Samudyata S, Sellgren CM. Human oligodendrocyte progenitor cells mediate synapse elimination through TAM receptor activation. Nat Commun 2025:16(1):10612.
244 Kauhanen J, Tiihonen J. Huumeiden terveysriskit Suomessa - voiko niitä hallita? HUUTI-tutkimuksen antia. Duodecim 2017:133(1):34-42.
245 Hamina A, Lavikainen P, Tanskanen A, Tolppanen A-M, Tiihonen J, Hartikainen S, Taipale H. Impact of opioid initiation on antipsychotic and benzodiazepine and related drug use among persons with Alzheimer's disease. Int Psychogeriatr 2018:30(7):947-956.
246 Häkkinen K, Kiiski JI, Lähteenvuo M, Jukuri T, Suokas K, Niemi-Pynttäri J, Kieseppä T, Männynsalo T, Wegelius A, Haaki W, Lahdensuo K, Kajanne R, Kaunisto MA, Tuulio-Henriksson A, Kampman O, Hietala J, Veijola J, ..., Tiihonen J, et al. Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder. Pharmacogenomics J 2022:22(3):166-172.
247 Tikkanen R, Tiihonen J, Rautiainen MR, Paunio T, Bevilacqua L, Panarsky R, Goldman D, Virkkunen M. Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon. Transl Psychiatry 2015:5:e681.
248 Luykx JJ, Stam N, Tanskanen A, Tiihonen J, Taipale H. In the aftermath of clozapine discontinuation: comparative effectiveness and safety of antipsychotics in patients with schizophrenia who discontinue clozapine. Br J Psychiatry 2020:217(3):498-505.
249 Tiihonen M, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S. Incidence and Duration of Cumulative Bisphosphonate Use among Community-Dwelling Persons with or without Alzheimer's Disease. J Alzheimers Dis 2016:52(1):127-32.
250 Sarycheva T, Taipale H, Lavikainen P, Tiihonen J, Tanskanen A, Hartikainen S, Tolppanen A-M. Incidence and Prevalence of Antiepileptic Medication Use in Community-Dwelling Persons with and without Alzheimer's Disease. J Alzheimers Dis 2018:66(1):387-395.
251 Taipale H, Särkilä H, Tanskanen A, Kurko T, Taiminen T, Tiihonen J, Sund R, Tuulio-Henriksson A, Saastamoinen L, Hietala J. Incidence of and Characteristics Associated With Long-term Benzodiazepine Use in Finland. JAMA Netw Open 2020:3(10):e2019029.
252 Høydal Nestvold H, Haarr E, Hamina A, Hjellvik V, Skurtveit S, Odsbu I. Incidence of and Determinants for Substance Use Disorders Among Individuals With Long-Term Prescription Opioid Use: A Population-Based Cohort Study. Pharmacoepidemiol Drug Saf 2025:34(9):e70212.
253 Hentilä E, Tiihonen M, Taipale H, Hartikainen S, Tolppanen A. Incidence of antidepressant use among community dwellers with and without Parkinson's disease - a nationwide cohort study. BMC Geriatr 2021:21(1):202.
254 Puranen A, Taipale H, Koponen M, Tanskanen A, Tolppanen AM, Tiihonen J, Hartikainen S. Incidence of antidepressant use in community-dwelling persons with and without Alzheimer's disease: 13-year follow-up. Int J Geriatr Psychiatry 2017:32(1):94-101.
255 Koponen M, Tolppanen AM, Taipale H, Tanskanen A, Tiihonen J, Johnell K, Fastbom J, Ahonen R, Hartikainen S. Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons. Br J Psychiatry 2015:207(5):444-9.
256 Saarelainen L, Taipale H, Koponen M, Tanskanen A, Tolppanen AM, Tiihonen J, Hartikainen S. The Incidence of Benzodiazepine and Related Drug Use in Persons with and without Alzheimer's Disease. J Alzheimers Dis 2015:49(3):809-18.
257 Saarelainen L, Taipale H, Koponen M, Tanskanen A, Tolppanen A-M, Tiihonen J, Hartikainen S, Tiihonen J, Hartikainen S. The Incidence of Benzodiazepine and Related Drug Use in Persons with and without Alzheimer's Disease. J Alzheimers Dis 2016:49(3):809-18.
258 Ilmaniemi S, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen AM. Incidence of head injury and traumatic brain injury among people with Alzheimer's disease. J Epidemiol Community Health 2019:73(5):451-454.
259 de Montgomery C, Cullen A, Taipale H, Krasnik A, Norredam M, Mittendorfer-Rutz E. Incidence of non-affective psychotic disorders in refugees and peers growing up in Denmark and Sweden. Soc Psychiatry Psychiatr Epidemiol 2024:59(7):1153-1165.
260 Tanskanen A, Taipale H, Cannon M, Cotter D, Tiihonen J. Incidence of schizophrenia and influence of prenatal and infant exposure to viral infectious diseases. Acta Psychiatr Scand 2021:143(6):487-494.
261 Taipale H, Hamina A, Karttunen N, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. Incident opioid use and risk of hip fracture among persons with Alzheimer disease: a nationwide matched cohort study. Pain 2019:160(2):417-423.
262 Hyttinen V, Taipale H, Tolppanen A-M, Tanskanen A, Tiihonen J, Hartikainen S, Valtonen H. Incident Use of a Potentially Inappropriate Medication and Hip Fracture in Community-Dwelling Older Persons With Alzheimer's Disease. Ann Pharmacother 2017:51(9):725-734.
263 Kostovski E, Hamina A, Hjellvik V, Clausen T, Skurtveit S. Increased cancer incidence and mortality among people with opioid use-related disorders: A nation-wide cohort study. Addiction 2024:119(9):1575-1584.
264 Laukkanen V, Kärkkäinen O, Kupila J, Kautiainen H, Tiihonen J, Storvik M. Increased metabotropic glutamate 2/3 receptor binding in the perigenual anterior cingulate cortex of cloninger type 2 alcoholics: a whole-hemisphere autoradiography study. Alcohol Alcohol 2015:50(1):62-67.
265 Kärkkäinen O, Häkkinen MR, Auriola S, Kautiainen H, Tiihonen J, Storvik M. Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics. Alcohol 2016:52:63-70.
266 Laukkanen V, Kärkkäinen O, Kautiainen H, Tiihonen J, Storvik M. Increased [³H]quisqualic acid binding density in the dorsal striatum and anterior insula of alcoholics: A post-mortem whole-hemisphere autoradiography study. Psychiatry Res Neuroimaging 2019:287:63-69.
267 Tikkanen R, Saukkonen T, Fex M, Bennet H, Rautiainen MR, Paunio T, Koskinen M, Panarsky R, Bevilacqua L, Sjöberg RL, Tiihonen J, Tiihonen J, Virkkunen M. Influence of a HTR2B stop codon on glucagon homeostasis and glucose excursion in non-diabetic men. Exp Clin Endocrinol Diabetes 2016:124(9):529-534.
268 Hietala E, Solismaa A, Lähteenvuo M, Ahola-Olli AV, Häkkinen K, Suokas K, Isometsä E, Suvisaari J, Kieseppä T, Holm M, Tiihonen J, Lönnqvist J, Hietala J, Wegelius A, Lahdensuo K, Haaki W, Kampman O. Influence of CYP2D6 phenotype on adherence, adverse effects, and attitudes in aripiprazole and risperidone users. Acta Neuropsychiatr 2025:37:e54.
269 Kauppila E, Vanninen E, Kaurijoki S, Karhunen L, Pietiläinen KH, Rissanen A, Tiihonen J, Pesonen U, Kaprio J. Influence of serotonin transporter gene polymorphism (5-HTTLPR Polymorphism) on the relation between brain 5-HT transporter binding and heart rate correcrted cardiac repolarization interval. PLoS ONE 2013:8(1):e50303.
270 Wingård L, Taipale H, Reutfors J, Westerlund A, Bodén R, Tiihonen J, Tanskanen A, Andersen M. Initiation and long-term use of benzodiazepines and Z-drugs in bipolar disorder. Bipolar Disord 2018:20(7):634-646.
271 Taipale H, Niederkrotenthaler T, Helgesson M, Sijbrandij M, Berg L, Tanskanen A, Mittendorfer-Rutz E. Initiation of antidepressant use among refugee and Swedish-born youth after diagnosis of a common mental disorder: findings from the REMAIN study . Soc Psychiatry Psychiatr Epidemiol 2021:56(3):463-474.
272 Mellin D, Mittendorfer-Rutz E, de Montgomery CJ, Cullen AE, Taipale H. Initiation of antipsychotic medication among refugees, non-refugee migrants, second-generation migrants, and Swedish-born adults with incident non-affective psychotic disorders. Soc Psychiatry Psychiatr Epidemiol 2025:60(12):2773-2784.
273 Odsbu I, Hamina A, Hjellvik V, Handal M, Haram M, Tesli M, Tanskanen A, Taipale H. Initiation of Antipsychotics During the First Year After First-Episode Psychosis: A Population-Based Study. Acta Psychiatr Scand 2025:151(4):537-547.
274 McCutcheon RA, Pillinger T, Varvari I, Halstead S, Ayinde OO, Crossley NA, Correll CU, Hahn M, Howes OD, Kane JM, Kabir T, Konradsson-Geuken Å, Lennox B, Hui CL, Rossell SL, Solmi M, Sommer IE, Taipale H, Uchida H, et al. INTEGRATE: international guidelines for the algorithmic treatment of schizophrenia. Lancet Psychiatry 2025:12(5):384-394.
275 Nielsen RE, Taipale H, Cortese S, Dragioti E, Du Rietz E, Firth J, Fusar-Poli P, Hartman C, Holt RIg, Høye A, Koyanagi A, Larsson H, Lehto K, Lindgren P, Manchia M, Nordentoft M, Skonieczna-Zydecka K, Stubbs B, Vancampfort D, Brandt L, et al. Integrating physical healthcare into psychiatry for severe mental illness: A narrative review and position statement from the ECNP PAN-Health group. Neurosci Appl 2026:5:106993.
276 Spathopoulou A, Sauerwein GA, Marteau V, Podlesnic M, Lindlbauer T, Kipura T, Hotze M, Gabassi E, Kruszewski K, Koskuvi M, Réthelyi JM, Apáti Á, Conti L, Ku M, Koal T, Müller U, Talmazan RA, Ojansuu I, Vaurio O, Lähteenvuo M, Tiihonen J, et al. Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia. Mol Psychiatry 2024:29(10):3128-3140.
277 Luykx JJ, Gonzalez-Diaz JM, Guu T, van der Horst MZ, van Dellen E, Boks MP, Guloksuz S, DeLisi LE, Sommer IE, Cummins R, Shiers D, Lee J, Every-Palmer S, Mhalla A, Chadly Z, Chan SK, Cotes RO, Takahashi S, Benros ME, Wagner E, ..., Tiihonen J, et al. An international research agenda for clozapine-resistant schizophrenia. Lancet Psychiatry 2023:10(8):644-652.
278 de Montgomery DJ, Faurholdt IM, Cullen AE, Taipale H, Mittendorfer-Rutz E, Krasnik A, Norredam M. Involuntary admissions for non-affective psychotic disorders in young refugees and peers in Denmark: A population cohort study. Schizophr Res 2024(270):366-371.
279 Räsänen N, Tiihonen J, Koskuvi M, Lehtonen S, Koistinaho J. The iPSC perspective on schizophrenia. Trends Neurosci 2022:45(1):8-26.
280 Taipale H, Hamina A, Lampela P, Tanskanen A, Tiihonen J, Karttunen N, Tolppanen A-M, Hartikainen S. Is Alzheimer's Disease Associated with Previous Opioid Use? Pain Med 2018:19(11):2115-2121.
281 Krivoy A, Tiihonen J, Nissan J, Dotan A, Arnheim D, Menkes-Caspi N, Taub S, Tuppurainen H, Mittendorfer-Rutz E, Davidson M, Davis JM, Weiser M, Taipale H. Is it Possible To Identify Patients After Their First Hospitalization for a Psychotic Disorder Who Do Not Use Anti-Psychotics and are Not Later Rehospitalized? Schizophr Bull 2026:52(1).
282 Paljarvi T, McPherson T, Luciano S, Herttua K, Fazel S. Isotretinoin and adverse neuropsychiatric outcomes: retrospective cohort study using routine data. Br J Dermatol 2022:187(1):64-72.
283 Antikainen R, Turunen H, Kuosmanen A, Haatainen K. Issues Related to Patient Participation in Psychiatric Hospital Care-An Integrative Literature Review of Patient Safety Research. J Clin Nurs 2025:34(4):1225-1239.
284 Rytkönen M. Kehityskulkuja ja väliintuloja. Ekologinen näkökulma vakavan väkivallanteon tehneiden nuorten sosioemotionaalisen terveyden kehitykseen. Väitöskirja. Kuopio: 2013. Publications of the University of Eastern Finland. Dissertations in Health Sciences 177. 137 s.
285 Särkilä H, Taipale H, Niemelä S. Ketkä päätyvät suuriannoksiseen bentsodiatsepiinien käyttöön? Duodecim 2025:141(12):969-71.
286 Keränen T, Kaski M, Scheinin M, Rinne J, Repo-Tiihonen E, Vartiainen H, Halila R, Heinonen S, Halkoaho A, Bendel S, Uusaro A, Turgut T, Roine RO, Launis V, Pasternack A. Kliininen tutkimus erityisryhmille. Kirjassa: Tapani Keränen, Amos Pasternack., toim. Kliinisen tutkimuksen etiikka : opas tutkijoille ja eettisille toimikunnille., s. 62-83. Helsinki: Duodecim, 2015.
287 Tiihonen J, Tanskanen A, Bell JS, Dawson JL, Kataja V, Taipale H. Klotsapiinihoitoon liittyy suurentunut hematologisen syövän riski. Duodecim 2022:138(9):843.
288 Purhonen M, Koponen H, Tiihonen J, Tanskanen A. Kun psyykenlääke vain katoaa. Pääkirjoitus. Duodecim 2014:130:438-439.
289 Orhan F, Malwade S, Khanlarkhani N, Gkogka A, Langeder A, Jungholm O, Koskuvi M, Lehtonen S, Schwieler L, Jardemark K, Tiihonen J, Koistinaho J, Erhardt S, Engberg G, Samudyata S, Sellgren CM. Kynurenic acid and promotion of activity-dependent synapse elimination in schizophrenia. Am J Psychiatry 2025:182(4):389-400.
290 Armannsdottir B, Taipale H, Akhtar A, Kautzky A, Björkenstam E, Lieslehto J, Tiihonen J, Lieslehto J, Amin R, Mittendorfer-Rutz E. Labor market marginalization in individuals with bipolar disorder: a Swedish nationwide register-based sibling comparison study. Psychol Med 2024:54(16):1-11.
291 Chen L, Mittendorfer-Rutz E, Björkenstam E, Rahman S, Gustafsson K, Kjeldgård L, Ekselius L, Taipale H, Tanskanen A, Helgesson M. Labour market integration among young adults diagnosed with attention-deficit/hyperactivity disorder (ADHD) at working age. Psychol Med 2024:54(1):148-158.
292 Helgesson M, Björkenstam E, Rahman S, Gustafsson K, Taipale H, Tanskanen A, Ekselius L, Mittendorfer-Rutz E. Labour market marginalisation in young adults diagnosed with attention-deficit hyperactivity disorder (ADHD): a population-based longitudinal cohort study in Sweden. Psychol Med 2023:53(4):1224-1232.
293 Lavikainen P, Koponen M, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. Length of Hospital Stay for Hip Fracture and 30-Day Mortality in People With Alzheimer's Disease: A Cohort Study in Finland. J Gerontol A Biol Sci Med Sci 2020:75(11):2184-2192.
294 Luykx JJ, Corbeil O, Kärkkäinen O, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J, Taipale H. Long term safety of ADHD medication in patients with schizophrenia spectrum disorders. Mol Psychiatry 2025:30(10):4859-4867.
295 Pacchiarotti I, Tiihonen J, Kotzalidis GD, Verdolini N, Murru A, Goikolea JM, Valentí M, Aedo A, Vieta E. Long-acting injectable antipsychotics (LAIs) for maintenance treatment of bipolar and schizoaffective disorders: A systematic review. Eur Neuropsychopharmacology 2019:29(4):457-470.
296 Taipale H, Tanskanen A, Kurko T, Taiminen T, Särkilä H, Tiihonen J, Sund R, Niemelä S, Saastamoinen L, Hietala J. Long-term benzodiazepine use and risk of labor market marginalization in Finland: A cohort study with 5-year follow-up. Eur Psychiatry 2024:67(1):e34.
297 Rubio JM, Taipale H, Tanskanen A, Correll CU, Kane JM, Tiihonen J. Long-term Continuity of Antipsychotic Treatment for Schizophrenia: A Nationwide Study. Schizophr Bull 2021:47(6):1611-1620.
298 Rubio JM, Kane JM, Tanskanen A, Tiihonen J, Taipale H. Long-term persistence of the risk of agranulocytosis with clozapine compared with other antipsychotics: a nationwide cohort and case-control study in Finland. Lancet Psychiatry 2024:11(6):443-450.
299 Lintunen J, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J, Lähteenvuo M. Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder. Schizophr Bull 2021:47(4):1099-1107.
300 Taipale H, Rysä J, Hukkanen J, Koponen M, Tanskanen A, Tiihonen J, Kröger H, Hartikainen S, Tolppanen A. Long-term thiazide use and risk of low-energy fractures among persons with Alzheimer's disease-nested case-control study. Osteoporos Int 2019:30(7):1481-1489.
301 Tiihonen J, Tanskanen A, Bell JS, Dawson JL, Kataja V, Taipale H. Long-term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-control and cohort study in Finland. Lancet Psychiatry 2022:9(5):353-362.
302 Koponen M, Taipale H, Tanskanen A, Tolppanen AM, Tiihonen J, Ahonen R, Hartikainen S. Long-term use of antipsychotics among community-dwelling persons with Alzheimer?s disease: A nationwide register-based study. Eur Neuropsychopharmacology 2015:25(10):1706-13.
303 Taipale H, Koponen M, Tanskanen A, Tolppanen A, Tiihonen J, Hartikainen S. Long-term use of benzodiazepines and related drugs among community-dwelling individuals with and without Alzheimer's disease. Int Clin Psychopharmacol 2015:30(4):202-8.
304 Laitinen H, Tiihonen M, Tanskanen A, Tiihonen J, Lieslehto J, Koponen M, Taipale H. Long-Term Use of Benzodiazepines and Related Drugs in Persons With Major Depressive Disorder. Brain Behav 2025:15(11):e71085.
305 Kurko TA, Saastamoinen LK, Tähkäpää S, Tuulio-Henriksson A, Taiminen T, Tiihonen J, Airaksinen MS, Hietala J. Long-term use of benzodiazepines: Definitions, prevalence and usage patterns - a systematic review of register-based studies. Eur Psychiatry 2015:30(8):1037-47.
306 Hamina A, Taipale H, Tanskanen A, Tolppanen A, Karttunen N, Pylkkänen L, Tiihonen J, Hartikainen S. Long-term use of opioids for nonmalignant pain among community-dwelling persons with and without Alzheimer disease in Finland: a nationwide register-based study. Pain 2017:158(2):252-260.
307 Juntunen H, Taipale H, Tanskanen A, Tolppanen A, Tiihonen J, Hartikainen S, Tiihonen M. Long-term use of proton pump inhibitors among community-dwelling persons with and without Alzheimer's disease. Eur J Clin Pharmacol 2017:73(9):1149-1158.
308 Kärkkäinen O, Laukkanen V, Haukijärvi T, Kautiainen H, Tiihonen J, Storvik M. Lower [3H]Citalopram binding in brain areas related to social cognition in alcoholics. Alcohol Alcohol 2015:50(1):46-50.
309 Tiihonen J. Lääkehoito voi vähentää psyykkisiin sairauksiin liittyvää ennenaikaista kuolleisuutta. Suomen Lääkärilehti 2022:77(47-48):1999.
310 Lieslehto J, Rantanen N, Oksanen LA, Oksanen SA, Kivimäki A, Paju S, Pietiäinen M, Lahdentausta L, Pussinen P, Anttila V, Lehtonen L, Lallukka T, Geneid A, Sanmark E. A machine learning approach to predict resilience and sickness absence in the healthcare workforce during the COVID-19 pandemic. Sci Rep 2022:12(1):8055.
311 Lieslehto J, Tiihonen J, Lähteenvuo M, Kautzky A, Akhtar A, Ármannsdóttir B, Leucht S, Correll CU, Mittendorfer-Rutz E, Tanskanen A, Taipale H. Machine learning-based mortality risk assessment in first-episode bipolar disorder: a transdiagnostic external validation study. EClinicalMedicine 2025:81:103108.
312 Maron E, Baldwin DS, Balotsev R, ..., Lähteenvuo M, ..., Tiihonen J, et al. Manifesto for an international digital mental health network. Digital Psychiatry 2019:2(1):14-24.
313 Isohanni M, Jääskeläinen E, Miller BJ, Hulkko A, Tiihonen J, Möller H-J, Hartikainen S, Huhtaniska S, Lieslehto J. Medication management of antipsychotic treatment in schizophrenia - a narrative review. Hum Psychopharmacol Clin Exp 2021:36:e2765.
314 Hamina A, Tanskanen A, Tiihonen J, Taipale H. Medication Use and Health Care Utilization After a Cost-sharing Increase in Schizophrenia: A Nationwide Analysis. Med Care 2020:58(9):763-769.
315 Holm M, Tanskanen A, Tiihonen J, Taipale H. Medication use and sickness absence from work in bipolar disorder: a nationwide register-based study. World Psychiatry 2024:23(2):296-298.
316 Agorastos A, Thompson T, Solmi M, Cortese S, Estradé A, Radua J, Dragioti E, Vancampfort D, Thygesen LC, Aschauer H, Schlögelhofer M, Aschauer E, Schneeberger A, Huber CG, Hasler G, Conus P, Do Cuénod KQ, ..., Tiihonen J, et al. Mental health, coping and related risk factors during the first 2 years of the COVID-19 pandemic in children: Nationally representative, multi-wave, cross-sectional results from 12 countries from the global COH-FIT study. Eur Neuropsychopharmacology 2026:104:112741.
317 Rantanen N, Lieslehto J, Oksanen L-M, Oksanen SA, Anttila V-J, Lehtonen L, Geneid A, Sanmark E. Mental well-being of healthcare workers in 2 hospital districts during the first wave of the COVID-19 pandemic in Finland: a cross-sectional study. Int J Occup Environ Health 2022:35(6):707-718.
318 Masvosva W, Lehtonen M, Martiskainen M, Tiihonen J, Karhunen PJ, Hanhineva K, Rysä J, Kok E, Kärkkäinen O. Metabolic Alterations in Human Post-Mortem Frontal Cortex and Cerebrospinal Fluid Associated With High Levels of Nicotine Metabolite Cotinine. Addict Biol 2025:30(6):e70064.
319 Kuokkanen R, Lappalainen R, Repo-Tiihonen E, Tiihonen J. Metacognitive group training for forensic and dangerous non-forensic patients with schizophrenia: A randomised controlled feasibility trial. Crim Behav Ment Health 2014:24(5):345-57.
320 Sluggett JK, Koponen M, Bell JS, Taipale H, Tanskanen A, Tiihonen J, Uusitupa M, Tolppanen A, Hartikainen S. Metformin and Risk of Alzheimer's Disease Among Community-Dwelling People With Diabetes: A National Case-Control Study. J Clin Endocrinol Metab 2020:105(4):dgz234.
321 Kupila J, Kärkkäinen O, Laukkanen V, Tupala E, Tiihonen J, Storvik M. mGluR1/5 receptor densities in the brains of alcoholic subjects: A whole-hemisphere autoradiography study. Psychiatry Res Neuroimaging 2013:212:245-250.
322 Räsänen N, Tiihonen J, Koskuvi M, Trontti K, Cheng L, Hill AF, Lehtonen S, Vaurio O, Ojansuu I, Lähteenvuo M, Pietiläinen O, Koistinaho J. miRNA profiling of hiPSC-derived neurons from monozygotic twins discordant for schizophrenia. Schizophrenia (Heidelb) 2025:11(1):21.
323 Rauhala A, Kinnunen M, Kuosmanen A, Liukka M, Olin K, Sahlström M, Roine RP. Mitä vapaaehtoiset vaaratapahtumailmoitukset kertovat? Suomen Lääkärilehti 2018:73(46):2716-2720.
324 Tiihonen J, Koskuvi M, Lähteenvuo M, Trontti K, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Cheng L, Tanskanen A, Taipale H, Lehtonen S, Koistinaho J. Molecular signaling pathways underlying schizophrenia. Schizophr Res 2021:232:33-41.
325 Ekholm O, Herling SF, Lykke C, Skurtveit S, Hamina A, Sjøgren P, Kurita GP. Monitoring Chronic Non-Cancer Pain in Denmark Over Two Decades: Prevalence, Mental Health and Loneliness. Eur J Pain 2025:29(2):e4776.
326 Checknita D, Bendre M, Ekström TJ, Comasco E, Tiihonen J, Hodgins S, Nilsson KW. Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour. Behav Brain Res 2020:382:112476.
327 Tolppanen A, Ahonen R, Koponen M, Lavikainen P, Purhonen M, Taipale H, Tanskanen A, Tiihonen J, Tiihonen M, Hartikainen S. Month and Season of Birth as a Risk Factor for Alzheimer's Disease: A Nationwide Nested Case-control Study. J Prev Med Public Health 2016:49(2):134-8.
328 Lähteenvuo M, Batalla A, Luykx JJ, Mittendorfer-Rutz E, Tanskanen A, Tiihonen J, Taipale H. Morbidity and mortality in schizophrenia with comorbid substance use disorders. Acta Psychiatr Scand 2021:144(1):42-49.
329 Uosukainen H, Kauhanen J, Bell JS, Ronkainen K, Tiihonen J, Föhr J, Onyeka IN, Korhonen MJ. Mortality among clients seeking treatment for buprenorphine abuse in Finland. Drug Alcohol Depend 2013:133:391-397.
330 Ojansuu I, Putkonen H, Tiihonen J. Mortality among forensic psychiatric patients in Finland. Nord J Psychiatry 2015:69(1):25-7.
331 Rolova G, Engeland A, Pedersen L, Odsbu I, Hamina A, Skurtveit S. Mortality among patients with long-term prescription opioid use in Norway: a nationwide registry-based cohort study. Pain 2025:166(11):e555-e562.
332 Tiihonen J, Mittendorfer-Rutz E, Torniainen M, Alexanderson K, Tanskanen A. Mortality and Cumulative Exposure to Antipsychotics, Antidepressants, and Benzodiazepines in Patients With Schizophrenia: An Observational Follow-Up Study. Am J Psychiatry 2016:173(6):600-6.
333 Correll CU, Solmi M, Croatto G, Kolton Schneider L, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J. Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World Psychiatry 2022:21(2):248-271.
334 Paljärvi T, Tiihonen J, Lähteenvuo M, Tanskanen A, Fazel S, Taipale H. Mortality in psychotic depression: 18-year follow-up study. Br J Psychiatry 2023:222(1):37-43.
335 Tanskanen A, Tiihonen J, Taipale H. Mortality in schizophrenia: 30-year nationwide follow-up study. Acta Psychiatr Scand 2018:138(6):492-499.
336 Thomson A, Tiihonen J, Miettunen J, Virkkunen M, Lindberg N. Mortality of firesetters: a follow-up study of Finnish male firesetters who underwent a pretrial forensic examination in 1973-1998. Psychiatry Res 2015:225(3):638-42.
337 Lebel JL, Duxbury JA, Putkonen A, Sprague T, Rae C, Sharpe J. Multinational experiences in reducing and preventing the use of restraint and seclusion. J Psychosoc Nurs Ment Health Serv 2014:52(11):22-9.
338 Sun L, Lukkarinen L, Putkinen V, Karlsson HK, Hirvonen J, Tiihonen J, Lauerma H, Scott S, Nummenmaa L. Mu-opioid receptor system modulates responses to vocal bonding and distress signals in humans. Philos Trans R Soc Lond B Biol Sci 2022:377(1863):20210181.
339 Heikkinen M, Taipale H, Tanskanen A, Mittendorfer-rutz E, Lähteenvuo M, Tiihonen. Naltreksoni vähentää alkoholiongelmaisten sairaalahoitoja. Duodecim 2021:137(4):427.
340 Lumén K, Louheranta O, Kuosmanen L. A narrative of recovery in forensic hospitals. Arch Psychiatr Nurs 2024:51:120-126.
341 Tuppurainen H, Määttä S, Könönen M, Julkunen P, Kautiainen H, Hyvärinen S, Vaurio O, Joensuu M, Vanhanen M, Aho-Mustonen K, Mervaala E, Tiihonen J. Navigated and individual [alpha]-peak-frequency-guided transcranial magnetic stimulation in male patients with treatment-refractory schizophrenia. J Psychiatry Neurosci 2024:49(2):E87-E95.
342 Tiihonen J, Koskuvi M, Lähteenvuo M, Virtanen PL, Ojansuu I, Vaurio O, Gao Y, Hyötyläinen I, Puttonen KA, Repo-Tiihonen E, Paunio T, Rautiainen M, Tyni S, Koistinaho J, Lehtonen S. Neurobiological roots of psychopathy. Mol Psychiatry 2020:25(12):3432-3441.
343 Paljärvi T, McPherson T, Thompson C, Luciano S, Herttua K, Fazel S. Neuropsychiatric diagnoses after isotretinoin initiation in pediatric acne patients: A retrospective cohort study. J Am Acad Dermatol 2024:91(3):571-573.
344 Paljärvi T, Forton JT, Thompson C, Luciano S, Herttua K, Fazel S. Neuropsychiatric diagnoses after montelukast initiation in paediatric patients with asthma. Thorax 2025:80(1):9-15.
345 Taipale H, Tolppanen A-M, Tiihonen M, Tanskanen A, Lic P, Tiihonen J, Hartikainen S. No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer's Disease. Am J Gastroenterol 2017:112(12):1802-1808.
346 Lintunen J, Lähteenvuo M, Tanskanen A, Tiihonen J, Taipale H. Non-adherence to mood stabilizers and antipsychotics among persons with bipolar disorder - A nationwide cohort study. J Affect Disord 2023:333:403-408.
347 Tenkanen H, Taskinen H, Kontio R, Repo-Tiihonen E, Tiihonen J, Kinnunen J. Nurses' Time Use in Forensic Psychiatry: Core Interventions Outlined in the Finnish Clinical Practice Guideline on Schizophrenia. J Forensic Nurs 2016:12(2):64-73.
348 Kuosmanen A, Tiihonen J, Repo-Tiihonen E, Eronen M, Turunen H. Nurses' views highlight a need for the systematic development of patient safety culture in forensic psychiatry nursing. J Patient Saf 2021:17(3):e228-e233.
349 Gémes K, Björkenstam E, Rahman S, Gustafsson K, Taipale H, Tanskanen A, Ekselius L, Mittendorfer-Rutz E, Helgesson M. Occupational Branch and Labor Market Marginalization among Young Employees with Adult Onset of Attention Deficit Hyperactivity Disorder-A Population-Based Matched Cohort Study. Int J Environ Res Public Health 2022:19(12):7254.
350 Askola R, Louheranta O, Soininen P, Putkonen H, Åstedt-Kurki P, Paavilainen E. The Offense as Perceived by the Parents of Forensic Psychiatric Patients. Issues Ment Health Nurs 2017:38(9):705-711.
351 Tiihonen J. Oikeuspsykiatria. Kirjassa: Lönnqvist J, Henriksson M, Marttunen M, Partonen T, toim. Psykiatria, s. 697-715. Helsinki: Duodecim, 2014.
352 Tiihonen J. Oikeuspsykiatria. Kirjassa: Lönnqvist J, Marttunen M, Henriksson M, Partonen T, toim. Psykiatria, s. pkr02500. Duodecim, 2017.
353 Tiihonen J. Oikeuspsykiatria. Kirjassa: Lönnqvist J, Henriksson M, Marttunen M, Partonen T, toim. Psykiatria, s. 825-843. Helsinki: Duodecim, 2021.
354 Askola R, Nikkonen M, Vuorio O, Kylmä J. Oikeuspsykiatrisen potilaan toivottomuus ja toivo hoitosuhteessa. Pro terveys 2013(2):20-22.
355 Kivimies K, Repo-Tiihonen E, Kautiainen H, Maaranen P, Muhonen LH, Heikkinen M, Tiihonen J. Opioid abuse and hospitalization rates in patients with schizophrenia. Nord J Psychiatry 2016:70(2):128-32.
356 Lintula E, Tiihonen M, Taipale H, Tolppanen A, Tanskanen A, Tiihonen J, Hartikainen S, Hamina A. Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease. Drugs Aging 2020:37(3):193-203.
357 Taipale H, Tanskanen A, Luykx JJ, Solmi M, Leucht S, Correll CU, Tiihonen J. Optimal Doses of Specific Antipsychotics for Relapse Prevention in a Nationwide Cohort of Patients with Schizophrenia. Schizophr Bull 2022:48(4):774-784.
358 Mustonen A, Niemelä S, Denissoff A, Forti MDi, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J, Taipale H. Optimizing antipsychotic dosing for relapse prevention in cannabis-induced psychosis: A nationwide cohort study. Psychiatry Res 2026:358:116966.
359 Lagerberg T, Gustafsson TT, Molero Y, Forton J, Sariaslan A, Chang Z, Larsson H, Lichtenstein P, Fazel S. Oral glucocorticoids and risk of psychiatric and suicidal behaviour outcomes: population-based cohort study. Br J Psychiatry 2026:229(1):43-50.
360 Makkonen P, Putkonen A, Korhonen J, Kuosmanen L, Kärkkäinen J. Pakon käytön vähentäminen ja turvallisuuden lisääminen psykiatrisessa hoidossa. Helsinki: Terveydenhuollon ja hyvinvoinnin laitos, 2016. THL Työpaperi 35. 44 s.
361 Kuosmanen L, Laukkanen E. Pakon käytön vähentäminen psykiatrisessa sairaalahoidossa. Duodecim 2019:135(10):925-931.
362 Cullen AE, Lindsäter E, Rahman S, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Helgesson M. Patient factors associated with receipt of psychological and pharmacological treatments among individuals with common mental disorders in a Swedish primary care setting. BJPsych Open 2023:9(2):e40.
363 Hipp K, Repo-Tiihonen E, Kuosmanen L, Katajisto J, Kangasniemi M. Patient participation in pro re nata medication in forensic psychiatric care: A nursing document analysis. J Psychiatr Mental Health Nurs 2021:28(4):611-621.
364 Hipp K, Kuosmanen L, Repo-Tiihonen E, Leinonen M, Louheranta O, Kangasniemi M. Patient participation in pro re nata medication in psychiatric inpatient settings: An integrative review. Int J Ment Health Nurs 2018:27(2):536-554.
365 Kuosmanen A. Patient Safety Culture in Forensic Psychiatric Hospital Care. Health Care Staff Perceptions'. Doctoral dissertation. Kuopio: University of Eastern Finland, 2021. Publications of the University of Eastern Finland. Dissertations in Health Sciences 648. 89 p.
366 Kuosmanen A, Tiihonen J, Repo-Tiihonen E, Eronen M, Turunen H. Patient safety culture in two Finnish state-run forensic psychiatric hospitals. J Forensic Nurs 2013:9(4):207-216.
367 Asikainen J, Vehviläinen-Julkunen K, Repo-Tiihonen E, Louheranta O. Patients' Perceptions of Safety and Debriefing in Forensic Mental Health Care in Finland. J Forensic Nurs 2023:19(3):187-196.
368 Onyeka IN, Beynon CM, Hannila ML, Tiihonen J, Föhr J, Tuomola P, Kuikanmäki O, Tasa N, Paasolainen M, Kauhanen J. Patterns and 14-year trends in mortality among illicit drug users in Finland: the HUUTI study. Int J Drug Policy 2014:25(6):1047-53.
369 Popovic D, Wertz M, Geisler C, Kaufmann J, Lähteenvuo M, Lieslehto J, Witzel J, Bogerts B, Walter M, Falkai P, Koutsouleris N, Schiltz K. Patterns of risk-Using machine learning and structural neuroimaging to identify pedophilic offenders. Front Psychiatry 2023:14:1001085.
370 Taipale H, Niederkrotenthaler T, Tanskanen A, Cullen AE, Helgesson M, Berg L, Sijbrandij M, Klimek P, Mittendorfer-Rutz E. Persistence of antidepressant use among refugee youth with common mental disorder. J Affect Disord 2021:294:831-837.
371 Stam N, Taipale H, Tanskanen A, Isphording L, Okhuijsen-Pfeifer C, Schuiling-Veninga CC, Bos JH, Bijker BJ, Tiihonen J, Luykx JJ. Persistence of Antipsychotic Use After Clozapine Discontinuation: A Real-World Study Across Antipsychotics. Clin Transl Sci 2020:13(6):1170-1177.
372 Giuliani L, Pezzella P, Giordano GM, Perrottelli A, Mucci A, Bucci P, Bitter I, Arango C, Luykx JJ, Díaz-Caneja CM, Ebdrup BH, Davidson M, Tiihonen J, Winter-van Rossum I, Galderisi S. Persistent negative symptoms in the EULAST cohort: impact on functional outcome. Schizophrenia (Heidelb) 2026:12(1):36.
373 Tiihonen J, Tanskanen A, Hoti F, Vattulainen P, Taipale H, Mehtälä J, Lähteenvuo M. Pharmacological treatments and risk of readmission to hospital for unipolar depression in Finland: a nationwide cohort study. Lancet Psychiatry 2017:4(7):547-553.
374 Fabiano N, Gupta A, Wong S, Tran J, Mohammad IYz, Bal S, Fiedorowicz JG, Firth J, Stubbs B, Vancampfort D, Schuch FB, Carr LJ, Shorr R, Cortese S, Manchia M, Hartman CA, Høye A, Fusar-Poli P, Koyanagi A, ..., Taipale H, et al. Physical activity, suicidal ideation, suicide attempt and death among individuals with mental or other medical disorders: A systematic review of observational studies. Neurosci Biobehav Rev 2024:158:105547.
375 Solmi M, Estradé A , Thompson T, Agorastos A, Radua J, ..., Tiihonen J, et al. Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A). . J Affect Disord 2022:299:367-376.
376 Kuokkanen R, Aho-Mustonen K, Muotka J, Lappalainen R, Tiihonen J. A Pilot Study of Group Administered Metacognitive Training (MCT) for Schizophrenia Patients in a High-Security Forensic Setting: Subjective Training Success and Health-Related Quality of Life. J Forensic Psychol Pract 2015:15(4):344-362.
377 Jokinen J, Königsson J, Moberg T, Jönsson EG, Tiihonen J, Nordström P, Oreland L, Åsberg M. Platelet monoamine oxidase activity and interpersonal violence in male suicide attempters. Psychiatry Res 2018:260:173-176.
378 Luykx JJ, Correll CU, Manu P, Tanskanen A, Hasan A, Tiihonen J, Taipale H. Pneumonia Risk, Antipsychotic Dosing, and Anticholinergic Burden in Schizophrenia. JAMA Psychiatry 2024:81(10):967-975.
379 Paloneva J, Autti T, Hakola P, Haltia MJ. Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy. In: Adam MP, Ardinger HH, Pagon RA, et al, eds. GeneReviews [Internet], https://www.ncbi.nlm.nih.gov/books/. Seattle (WA), USA: University of Washington, 2020.
380 Koch E, Kämpe A, Alver M, Sigurðarson S, Einarsson G, Partanen J, Smith RL, Jaholkowski P, Taipale H, Lähteenvuo M, Steen NEiel, Smeland OB, Djurovic S, Molden E, Molden E, Molden E, Sigurdsson E, Stefánsson H, Stefánsson K, Palotie A, et al. Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study. Neuropsychopharmacology 2024:49(7):1113-1119.
381 Onyeka IN, Beynon CM, Vohlonen I, Tiihonen J, Föhr J, Ronkainen K, Kauhanen J. Potential Years of Life Lost Due to Premature Mortality Among Treatment-Seeking Illicit Drug Users in Finland. J Community Health 2015:40(6):1099-106.
382 Vattulainen P, Tanskanen A, Taipale H. PRE2DUP-R, advanced, open science method to estimate drug use periods for pharmacoepidemiology. Int J Med Inf 2026:212:106344.
383 Stenius J, Knekt P, Heinonen E, Holma J, Antikainen R, Lindfors O. Predicting the working alliance over the course of long-term psychodynamic psychotherapy with the Rorschach Ego Impairment Index, self-reported defense style, and performance-based intelligence: An evaluation of three methodological approaches. Psychoanal Psychol 2021:38(1):58-67.
384 Paavola J, Huuskonen T, von Und Zu Fraunberg M, Koivisto T, Kämäräinen O, Lång M, Lähteenvuo M, Jääskeläinen JE, Huttunen J, Lindgren A. The predictive role of family history of antipsychotic drug use in poor outcomes following aneurysmal subarachnoid hemorrhage (aSAH). Brain Spine 2025:5:104317.
385 Stenberg J-H, Terevnikov V, Joffe M, Tiihonen J, Chukhin E, Burkin M, Joffe G. Predictors and mediators of add-on mirtazapine-induced cognitive enhancement in schizophrenia - A path model investigation. Neuropharmacology 2013:64:248-253.
386 Scheen L, Brandt L, Bodén R, Tiihonen J, Andersen M, Kieler H, Reutfors J. Predictors for initiation of pharmacological prophylaxis in patients with newly diagnosed bipolar disorder - A nationwide cohort study. J Affect Disord 2015:172:204-210.
387 Kalamägi J, Lavikainen P, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. Predictors of high hospital care and medication costs and cost trajectories in community-dwellers with Alzheimer's disease. Ann Med 2019:51(5):294-305.
388 Hamina A, McDonald R, Skurtveit S. Pregabalin is associated with a higher overdose risk but the risk with gabapentin is not negligible. Pain 2025:166(2):463-464.
389 Hamina A, Muller AE, Clausen T, Skurtveit S, Hesse M, Tjagvad C, Thylstrup B, Odsbu I, Zoega H, Jónsdóttir HL, Taipale H. Prescription opioids among older adults: ten years of data across five countries. BMC Geriatr 2022:22(1):429.
390 van Deursen D, Mittendorfer-Rutz E, Taipale H, Pettersson E, McGuire P, Fusar-Poli P, Joyce DW, Albert N, Erlangsen A, Nordentoft M, Hjorthøj C, Cervenka S, Cullen AE. Prevalence and predictors of healthcare use for psychiatric disorders at 9 years after a first episode of psychosis: a Swedish national cohort study. BMJ Ment Health 2025:28(1):e301248.
391 Vu M, Koponen M, Taipale H, Tanskanen A, Tiihonen J, Kettunen R, Hartikainen S, Tolppanen A. Prevalence of cardiovascular drug use before and after diagnosis of Alzheimer's disease. Int J Cardiol 2020:300:221-225.
392 Taipale H, Vuorikari H, Tanskanen A, Koponen M, Tiihonen J, Kettunen R, Hartikainen S. Prevalence of Drug Combination Increasing Bleeding Risk Among Warfarin Users With and Without Alzheimer’s Disease. Drugs Aging 2015:32(11):937-45.
393 Babar BA, Vu M, Koponen M, Taipale H, Tanskanen A, Kettunen R, Tiihonen M, Hartikainen S, Tolppanen A. Prevalence of oral anticoagulant use among people with and without Alzheimer's disease. BMC Geriatr 2022:22(1):464.
394 Asikainen J. Prevention Of Coercive Action In Forensic Psychiatric Inpatient Care - Use Of Debriefing. Doctoral dissertation. Kuopio: University of Eastern Finland, 2022. Publications of the University of Eastern Finland. Dissertations in Health Sciences 696. 111 p.
395 Kivimies K, Repo-Tiihonen E, Kautiainen H, Tiihonen J. Previous forensic mental examination is a useful marker indicating effective violence relapse prevention among psychotic patients. Nord J Psychiatry 2014:68(5):311-5.
396 Lieslehto J, Tiihonen J, Lähteenvuo M, Tanskanen A, Taipale H. Primary Nonadherence to Antipsychotic Treatment Among Persons with Schizophrenia. Schizophr Bull 2022:48(3):655-663.
397 Hipp K, Repo-Tiihonen E, Kuosmanen L, Katajisto J, Kangasniemi M. PRN medication events in a forensic psychiatric hospital: a document analysis of the prevalence and reasons. Int J Forensic Ment Health 2020:19(4):329-340.
398 Bramness JG, Hjorthøj C, Niemelä S, Taipale H, Rognli EB. Problematic diagnosis of substance-induced disorders in ICD-11. Eur Psychiatry 2024:67(1):e51.
399 Koskinen L1, Likitalo H, Aho J, Vuorio O, Meretoja R. The professional competence profile of Finnish nurses practising in a forensic setting. J Psychiatr Mental Health Nurs 2014:21(4):320-6.
400 Hallikainen I, Martikainen J, Lin PJ, Cohen J T, Lahoz R, Välimäki T, Hongisto K, Väätäinen S, Vanhanen M, Neumann P J, Hänninen T, Koivisto AM. The Progression of Alzheimer's Disease Can Be Assessed with a Short Version of the CERAD Neuropsychological Battery: The Kuopio ALSOVA Study. Dement Geriatr Cogn Disord Extra 2014(4):494-508.
401 Lieslehto J, Jääskeläinen E, Kiviniemi V, Haapea M, Jones PB, Murray GK, Veijola J, Dannlowski U, Grotegerd D, Meinert S, Hahn T, Ruef A, Isohanni M, Falkai P, Miettunen J, Dwyer DB, Koutsouleris N. The progression of disorder-specific brain pattern expression in schizophrenia over 9 years. NPJ Schizophr 2021:7(1):32.
402 Tiihonen J, Kataja V, Lähteenvuo M, Taipale H. Prolaktiinipitoisuutta suurentavat psykoosilääkkeet ja rintasyöpäriski rekisteritiedon valossa. Duodecim 2022:138(4):296-298.
403 Touitou-Burckard E, Gondek T, Isayeva U, Ernst Nielsen R, Taipale H, Tiihonen J, Boyer L, Gandré C, Gandré C. Protocol for a Delphi consensus study to identify priority characteristics of integrated care for individuals with severe mental illness and comorbid physical disorders in Europe. PLoS ONE 2026:21(7):e0352089.
404 Torvinen-Kiiskinen S, Tolppanen A-M, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Taipale H. Proton pump inhibitor use and risk of hip fractures among community-dwelling persons with Alzheimer's disease-a nested case-control study. Aliment Pharmacol Ther 2018:47(8):1135-1142.
405 Laukkanen E, Kuosmanen L, Louheranta O, Vehviläinen-Julkunen K. Psychiatric nursing managers' attitudes towards containment methods in psychiatric inpatient care. J Nurs Manag 2020:28(3):699-709.
406 Laukkanen E, Vehviläinen-Julkunen K, Louheranta O, Kuosmanen L. Psychiatric nursing staffs' attitudes towards the use of containment methods in psychiatric inpatient care: An integrative review. Int J Ment Health Nurs 2019:28(2):390-406.
407 Thomson A, Tiihonen J, Miettunen J, Sailas E, Virkkunen M, Lindberg N. Psychopathic traits among a consecutive sample of Finnish pretrial fire-setting offenders. BMC Psychiatry 2015:15:44.
408 Vaurio O, Tiihonen J, Lähteenvuo M, Lieslehto J. Psychopathic traits associate with later schizophrenia. Acta Psychiatr Scand 2025:152(6):432-440.
409 Vaurio O, Repo-Tiihonen E, Kautiainen H, Tiihonen J. Psychopathy and Mortality. J Forensic Sci 2018:63(2):474-477.
410 Lähteenvuo M, Antolin-Concha D, Vattulainen P, Tanskanen A, Taipale H, Tiihonen J. Psychopharmacological treatment, mortality and suicide in bipolar disorder in a Finnish nationwide cohort of 18,018 patients. Psychiatr Fenn 2018:49:10-21.
411 Ojansuu I, Lähteenvuo M, Tiihonen J, Lehti M, Putkonen H. Psychosis and the risk of stranger homicides. Schizophr Bull 2022:3(1):sgac021.
412 Rubio JM, Taipale H, Correll CU, Tanskanen A, Kane JM, Tiihonen J. Psychosis breakthrough on antipsychotic maintenance: results from a nationwide study. Psychol Med 2020:50(8):1356-1367.
413 Rubio JM, Schoretsanitis G, John M, Tiihonen J, Taipale H, Guinart D, Malhotra AK, Correll CU, Kane JM. Psychosis relapse during treatment with long-acting injectable antipsychotics in individuals with schizophrenia-spectrum disorders: an individual participant data meta-analysis. Lancet Psychiatry 2020:7(9):749-761.
414 Paljärvi T, Tiihonen J, Lähteenvuo M, Tanskanen A, Fazel S, Taipale H. Psychotic depression and deaths due to suicide. J Affect Disord 2023:321:28-32.
415 Tiihonen J, Lehti M, Aaltonen M, Kivivuori J, Kautiainen H, Virta L, Hoti F, Tanskanen A, Korhonen P. Psychotropic drugs and homicide: A prospective cohort study from Finland. World Psychiatry 2015:14(2):245-247.
416 Orsel K, Taipale H, Tolppanen A-M, Koponen M, Tanskanen A, Tiihonen J, Gardarsdottir H, Hartikainen S. Psychotropic drugs use and psychotropic polypharmacy among persons with Alzheimer's disease. Eur Neuropsychopharmacology 2018:28(11):1260-1269.
417 Bergström T, Hulkko A, Hartikainen S, Koponen H, Lieslehto J, Jääskeläinen E, Isohanni M. Psykoosilääkehoidon ohjaus voi tehostaa skitsofrenian hoitoa. Duodecim 2022:138(9):787-793.
418 Tiihonen J, Mittendorfer-rutz E, Majak M, Mehtälä J, Hoti F, Jedenius E, Enkusson D, Leval A, Sermon J, Tanskanen A, Taipale H. Psykoosilääkityksen vaikuttavuus skitsofrenian hoidossa. Duodecim 2017:133(15):1412.
419 Liehu M, Tiihonen M, Taipale H, Tanskanen A, Tiihonen J, Tolppanen A-M, Hartikainen S, Koponen M. Psykoosilääkkeiden käyttö on pitkäkestoista Alzheimerin tautia sairastavilla. Dosis 2020:2020(36):6-23.
420 Hallikainen T, Repo-Tiihonen E. Psykoottisen potilaan aggressio - ehkäisy ja hoito. Duodecim 2015:131(15):1361-6.
421 Nummenmaa L, Lukkarinen L, Sun L, Putkinen V, Seppälä K, Karjalainen T, Karlsson HK, Hudson M, Venetjoki N, Salomaa M, Rautio P, Hirvonen J, Lauerma H, Tiihonen J. Psykopatian aivomekanismit selviävät. Duodecim 2021:137(9):991-992.
422 Kettunen R, Suvisaari J, Tiihonen J, Ruskoaho H, Huikuri H. Psyykenlääkkeet ja sydän. Duodecim 2020:136(2):1411-8.
423 Tiihonen J, Ojansuu I, Lehti M. Päihdekäyttö ja riski syyllistyä muita vaarantaviin tekoihin. Duodecim 2021:137(22):2461-2466.
424 Kuosmanen A, Liukka M, Aaltonen L-M, Roine RP, Kinnunen M. Pääsyy vai syypää - potilasturvallisuuskulttuuri ratkaisee. Suomen Lääkärilehti 2018:73(8):518-519.
425 Mazumder AH, Barnett J, Isometsä ET, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Ahola-Olli A, Hietala J, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, ..., Tiihonen J, et al. Reaction time and visual memory in connection to alcohol use in persons with bipolar disorder. Brain Sci 2021:11(9):1154.
426 Mazumder AH, Barnett J, Isometsä ET, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Ahola-Olli A, Hietala J, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, ..., Tiihonen J, et al. Reaction time and visual memory in connection to hazardous drinking polygenic scores in schizophrenia, schizoaffective disorder and bipolar disorder. Brain Sci 2021:11(11):1422.
427 Mazumder AH, Barnett J, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Hietala J, Isometsä ET, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, ..., Tiihonen J, et al. Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder. Brain Sci 2021:11(6):688.
428 Puranen A, Koponen M, Lähteenvuo M, Tanskanen A, Tiihonen J, Taipale H. Real-world effectiveness of antidepressant use in persons with schizophrenia: within-individual study of 61,889 subjects. Schizophrenia (Heidelb) 2023:9(1):34.
429 Taipale H, Lieslehto J, Lähteenvuo M, Hamina A, Tanskanen A, Mittendorfer-Rutz E, Paljärvi T, Solmi M, Cipriani A, Correll CU, Tiihonen J. Real-world effectiveness of antidepressants, antipsychotics and their combinations in the maintenance treatment of psychotic depression. Evidence from within-subject analyses of two nationwide cohorts. World Psychiatry 2024:23(2):276-284.
430 Taipale H, Tanskanen A, Correll CU, Tiihonen J. Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study. Lancet Psychiatry 2022:9(4):271-279.
431 Mustonen A, Taipale H, Denissoff A, Ellilä V, Di Forti M, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J, Niemelä S. Real-world effectiveness of antipsychotic medication in relapse prevention after cannabis-induced psychosis. Br J Psychiatry 2026:228(4):317-323.
432 Tiihonen J, Mittendorfer-Rutz E, Majak M, Mehtälä J, Hoti F, Jedenius E, Enkusson D, Leval A, Sermon J, Tanskanen A, Taipale H. Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29?823 Patients With Schizophrenia. JAMA Psychiatry 2017:74(7):686-693.
433 Tiihonen J, Tiihonen J. Real-world effectiveness of antipsychotics. Editorial. Acta Psychiatr Scand 2016:134(5):371-373.
434 Taipale H, Siskind D, Tanskanen A, Mittendorfer-Rutz E, Correll CU, Tiihonen J. Real-world effectiveness of clozapine augmentation with antidepressants: within-subject data evidence from two European nationwide cohorts. Lancet Psychiatry 2025:12(8):568-578.
435 Brand BA, Sommer IE, Gangadin SS, Tanskanen A, Tiihonen J, Taipale H. Real-World Effectiveness of Menopausal Hormone Therapy in Preventing Relapse in Women With Schizophrenia or Schizoaffective Disorder. Am J Psychiatry 2024:181(10):893-900.
436 Puranen A, Koponen M, Lähteenvuo M, Tanskanen A, Tiihonen J, Taipale H. Real-world effectiveness of mood stabilizer use in schizophrenia. Acta Psychiatr Scand 2023:147(3):257-266.
437 Lähteenvuo M, Tanskanen A, Taipale H, Hoti F, Vattulainen P, Vieta E, Tiihonen J. Real-world effectiveness of pharmacologic treatments for the prevention of rehospitalization in a Finnish nationwide cohort of patients with bipolar disorder. JAMA Psychiatry 2018:75(4):347-355.
438 Ermis C, Taipale H, Tanskanen A, Vieta E, Correll CU, Mittendorfer-Rutz E, Tiihonen J. Real-world effectiveness of pharmacological maintenance treatment of bipolar depression: a within-subject analysis in a Swedish nationwide cohort. Lancet Psychiatry 2025:12(3):198-207.
439 Lähteenvuo M, Paljärvi T, Tanskanen A, Taipale H, Tiihonen J. Real-world effectiveness of pharmacological treatments for bipolar disorder: register-based national cohort study. Br J Psychiatry 2023:223(4):456-464.
440 Hartikainen M. Real-World Effectiveness of Pharmacological Treatments of Alcohol, Opioid and Amphetamine Use Disorders - Findings from Swedish National Register-Based Studies. Doctoral dissertation. Kuopio: University of Eastern Finland, 2024. Publications of the University of Eastern Finland. Dissertations in Health Sciences 822. 132 p.
441 Heikkinen M, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Lähteenvuo M, Tiihonen J. Real-world effectiveness of pharmacological treatments of alcohol use disorders in a Swedish nation-wide cohort of 125 556 patients. Addiction 2021:116(8):1990-1998.
442 Heikkinen M, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Lähteenvuo M, Tiihonen J. Real-world effectiveness of pharmacological treatments of opioid use disorder in a national cohort. Addiction 2022:117(6):1683-1691.
443 Taipale H, Tanskanen A, Correll CU, Tiihonen J. Real-world effectiveness studies of low doses of antipsychotics - Authors' reply. Lancet Psychiatry 2022:9(7):536-537.
444 Koistinaho A, Poranen J, Tanskanen A, Tiihonen J, Taipale H, Lähteenvuo M. Real-world use of pharmacological treatments for incident bipolar disorder: A Finnish nationwide cohort study. J Affect Disord 2023:340:237-244.
445 Putkonen A. Recovery From Cervical Dystonia With Topiramate. J Med Cases 2015:6(8):373-375.
446 Ermis C, Tanskanen A, Corbeil O, Lieslehto J, Vieta E, Correll CU, Mittendorfer-Rutz E, Tiihonen J, Taipale H. Reduced risk of cause-specific hospitalisations and all-cause hospitalisation/mortality during treatment with attention-deficit/hyperactivity disorder medications in the course of bipolar disorder: a Swedish registry-based within-subject cohort study. BMJ Ment Health 2026:29(1):e302159.
447 Wingård L, Bodén R, Brandt L, Tiihonen J, Tanskanen A, Kieler H, Andersen M, Reutfors J. Reducing the rehospitalization risk after a manic episode: A population based cohort study of lithium, valproate, olanzapine, quetiapine and aripiprazole in monotherapy and combinations. J Affect Disord 2017:217:16-23.
448 Tuovinen S. Reduction of Seclusion and Restraint and Hospital Violence During Involuntary Forensic Psychiatric Care. Doctoral dissertation. Kuopio: UEF, 2017. Publications of the University of Eastern Finland. Dissertations in Health Sciences 446. 54., append.
449 de Montgomery CJ, Rasmussen AF, Bergström J, Taipale H, Akhtar A, Krasnik A, Nørredam M, Mittendorfer-Rutz E, Cullen AE. Refugee Migration Background and Healthcare Contacts Prior to First-Episode Psychosis in Young Adults in Denmark and Sweden: Are Patterns Consistent Across Countries? Early Interv Psychiatry 2025:19(4):e70039.
450 Tolppanen A, Voutilainen A, Taipale H, Tanskanen A, Lavikainen P, Koponen M, Tiihonen J, Hartikainen S. Regional changes in psychotropic use among Finnish persons with newly diagnosed Alzheimer's disease in 2005-2011. PLoS ONE 2017:12(3):e0173450.
451 Solmi M, Croatto G, Fornaro M, Schneider LK, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J, Cortese S, Dragioti E, Rietz E, Nielsen RE, Firth J, Fusar-Poli P, Hartman C, Holt RI, Høye A, et al. Regional differences in mortality risk and in attenuating or aggravating factors in schizophrenia: A systematic review and meta-analysis. Eur Neuropsychopharmacology 2024:80:55-69.
452 Taipale H, Tiihonen J. Registry-based studies: What they can tell us, and what they cannot. Eur Neuropsychopharmacology 2021:45:35-37.
453 Tiihonen J, Taipale H, Correll CU. Rejoinder to rejoinder to commentary. Psychol Med 2020:50(16):2812-2813.
454 Howes OD, Bukala BR, Chen EY, Correll CU, Hasan A, Honer WG, Kane JM, Leucht S, Siafis S, Agid O, Akena D, Arango C, Atwoli L, Barnes TR, Birnbaum ML, Bitter I, Breier A, Buchanan RW, ..., Tiihonen J, et al. Relapse in Schizophrenia: A Systematic Review of Criteria for Clinical Studies and International Consensus Guidelines to Improve Them. Am J Psychiatry 2025:182(11):969-983.
455 Ellilä V, Taipale H, Tiihonen J, Mittendorfer-Rutz E, Niemelä S. Relapse in substance-induced psychosis and associated risk factors. A Nationwide register-linkage study from Sweden. Addiction 2025:120(7):1422-1430.
456 Lieslehto J, Tiihonen J, Lähteenvuo M, Kautzky A, Akhtar A, Amin R, Ármannsdóttir B, Leucht S, Correll CU, Mittendorfer-Rutz E, Tanskanen A, Taipale H. Relapse risk prediction in patients with first-episode bipolar disorder: development, external validation, and pharmacotherapy associations of a machine learning model. Mol Psychiatry 2025:30(12):5722-5730.
457 Terevnikov V, Stenberg J-H, Tiihonen J, Chukhin E, Joffe M, Burkin M, Joffe G. Relationships between pharmacotherapy-induced metabolic changes and improved psychopathology in schizophrenia: data from a mirtazapine and first-genedation antipsychotics combination trial. Int J Neuropsychopharmacol 2013:16:1661-1666.
458 Taipale H, Solmi M, Correll CU, Tiihonen J. Relative Risk of Breast Cancer Associated With Prolactin-Increasing Antipsychotic Use. J Clin Psychiatry 2024:85(1):23lr15135.
459 Kallioniemi E, Kärkkäinen O, Määttä S, Könönen M, Kivimäki P, Kaarre O, Velagapudi V, Kekkonen V, Lehto SM, Laukkanen E, Tolmunen T. Repeated Transcranial Magnetic Stimulation-Induced Motor Evoked Potentials Correlate With the Subject-Specific Serum Metabolic Profile of Creatine. J Clin Neurophysiol 2019:36(3):229-235.
460 Rolová G, Engeland A, Pedersen L, Odsbu I, Hamina A, Skurtveit S. Reply to the Chen and Chen. Pain 2025:166(10):e493-e494.
461 Hamina A, Pinzón-Espinosa J, Taipale H, Schneider-Thoma J, Radua J, Efthimiou O, Cardoner N, Correll CU, Fusar-Poli P, Mittendorfer-Rutz E, Penninx BW, Ruhe HG, Tanskanen A, Vinkers CH, Leucht S, Vieta E, Cipriani A, Tiihonen J, Luykx JJ. Representation and outcomes of individuals with major depression in routine care who are ineligible for randomized controlled trials: a nationwide register-based study. World Psychiatry 2026:25(1):117-124.
462 Taipale H, Schneider-Thoma J, Pinzón-Espinosa J, Radua J, Efthimiou O, Vinkers CH, Mittendorfer-Rutz E, Cardoner N, Pintor L, Tanskanen A, Tomlinson A, Fusar-Poli P, Cipriani A, Vieta E, Leucht S, Tiihonen J, Luykx JJ. Representation and Outcomes of Individuals With Schizophrenia Seen in Everyday Practice Who Are Ineligible for Randomized Clinical Trials. JAMA Psychiatry 2022:79(3):210-218.
463 Lähteenvuo M, Tiihonen J, Solismaa A, Tanskanen A, Mittendorfer-Rutz E, Taipale H. Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder. JAMA Psychiatry 2025:82(1):94-98.
464 Fazel S, Paljarvi T. Response to 'Isotretinoin and adverse neuropsychiatric outcomes: retrospective cohort study using routine data': reply from authors. Br J Dermatol 2022:187(3):450-451.
465 Tiihonen J. Response to the editorial on antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia. Schizophr Res 2018:202:397.
466 Taipale H, Reutfors J, Tanskanen A, Brandt L, Tiihonen J, DiBernardo A, Mittendorfer-Rutz E, Brenner P. Risk and risk factors for disability pension among patients with treatment resistant depression- a matched cohort study. BMC Psychiatry 2020:20(1):232.
467 Chen L, Mittendorfer-Rutz E, Björkenstam E, Rahman S, Gustafsson K, Taipale H, Tanskanen A, Ekselius L, Helgesson M. Risk Factors for Disability Pension among Young Adults Diagnosed with Attention-deficit Hyperactivity Disorder (ADHD) in Adulthood. J Atten Disord 2022:26(5):723-734.
468 Hyttinen V, Taipale H, Tanskanen A, Tiihonen J, Tolppanen AM, Hartikainen S, Valtonen H. Risk Factors for Initiation of Potentially Inappropriate Medications in Community-Dwelling Older Adults with and without Alzheimer's Disease. Drugs Aging 2017:34(1):67-77.
469 Reutfors J, Andersson TM, Tanskanen A, DiBernardo A, Li G, Brandt L, Brenner P. Risk factors for suicide and suicide attempts among patients with treatment-resistant depression: nested case-control study. Arch Suicide Res 2021:25(3):424-438.
470 Guinart D, Taipale H, Rubio JM, Tanskanen A, Correll CU, Tiihonen J, Kane JM. Risk Factors, Incidence, and Outcomes of Neuroleptic Malignant Syndrome on Long-Acting Injectable vs Oral Antipsychotics in a Nationwide Schizophrenia Cohort. Schizophr Bull 2021:47(6):1621-1630.
471 Solmi M, Miola A, Capone F, Pallottino S, Højlund M, Firth J, Siskind D, Holt RI, Corbeil O, Cortese S, Dragioti E, Du Rietz E, Nielsen RE, Nordentoft M, Fusar-Poli P, Hartman CA, Høye A, ..., Taipale H, et al. Risk factors, prevention and treatment of weight gain associated with the use of antidepressants and antipsychotics: a state-of-the-art clinical review. Expert Opin Drug Saf 2024:23(10):1249-1269.
472 Imtiaz B, Taipale H, Tanskanen A, Tiihonen M, Kivipelto M, Heikkinen A, Tiihonen J, Soininen H, Hartikainen S, Tolppanen A. Risk of Alzheimer's disease among users of postmenopausal hormone therapy: A nationwide case-control study. Maturitas 2017:98:7-13.
473 Tapiainen V, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A-M. The risk of Alzheimer's disease associated with benzodiazepines and related drugs: a nested case-control study. Acta Psychiatr Scand 2018:138(2):91-100.
474 Saarelainen L, Tolppanen A-M, Koponen M, Tanskanen A, Tiihonen J, Hartikainen S, Taipale H. Risk of death associated with new benzodiazepine use among persons with Alzheimer disease: A matched cohort study. Int J Geriatr Psychiatry 2018:33(4):583-590.
475 Di Thiene D, Helgesson M, Alexanderson K, La Torre G, Tiihonen J, Mittendorfer-Rutz E. Risk of disability pension in first and second generation immigrants: the role of age and region of birth in a prospective population-based study from Sweden. BMC Public Health 2017:17(1):931.
476 Taipale H, Koponen M, Tanskanen A, Lavikainen P, Sund R, Tiihonen J, Hartikainen S, Tolppanen A. Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer's disease: a nationwide matched cohort study. Alzheimers Res Ther 2017:9(1):59.
477 Tapiainen V, Lavikainen P, Koponen M, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen A. The Risk of Head Injuries Associated With Antipsychotic Use Among Persons With Alzheimer's disease. J Am Geriatr Soc 2020:68(3):595-602.
478 Saarelainen L, Tolppanen A-M, Koponen M, Tanskanen A, Sund R, Tiihonen J, Hartikainen S, Taipale H. Risk of Hip Fracture in Benzodiazepine Users With and Without Alzheimer Disease. J Am Med Dir Assoc 2017:18(1):87.e15-87.e21.
479 Di Thiene D, Helgesson M, Rahman S, Alexanderson K, Tiihonen J, La Torre G, Mittendorfer-Rutz E. Risk of labour market marginalisation among young refugees and non-refugee migrants with common mental disorders. Soc Psychiatry Psychiatr Epidemiol 2021:56(6):1025-1034.
480 Nestvold H, Skurtveit S, Hamina A, Hjellvik V, Odsbu I. The risk of long-term opioid use among immigrants: a national registry-linkage study. Scand J Public Health 2025:53(7):764-775.
481 Koponen M, Taipale H, Lavikainen P, Tanskanen A, Tiihonen J, Tolppanen AM, Ahonen R, Hartikainen S. Risk of Mortality Associated with Antipsychotic Monotherapy and Polypharmacy Among Community-Dwelling Persons with Alzheimer's Disease. J Alzheimers Dis 2017:56(1):107-118.
482 Taipale H, Tolppanen A, Koponen M, Tanskanen A, Lavikainen P, Sund R, Tiihonen J, Hartikainen S. Risk of pneumonia associated with incident benzodiazepine use among community-dwelling adults with Alzheimer disease. Can Med Assoc J 2017:189(14):E519-E529.
483 Tiihonen J, Tanskanen A, Taipale H. Risk of Treatment Failure: Response to Czobor and Volavka. Am J Psychiatry 2018:175(9):909.
484 Mastafa S, Montgomery C, Pettersson E, Norredam M, Krasnik A, Taipale H, Mittendorfer-Rutz E, Cullen A. Risk of unemployment and work disability among refugee and non-refugee migrants with incident psychotic disorders in Sweden and Denmark. Eur J Public Health 2024:34(1):129-135.
485 Holm M, Tanskanen A, Tiihonen J, Taipale H. The Role of Antipsychotics and Mood Stabilizers in Preventing Sickness Absence Among Employed Individuals With Bipolar Disorder: A Nationwide Register-Based Study. Acta Psychiatr Scand 2025:152(2):104-111.
486 Herttua K, Thapa S, Juel Ahrenfeldt L, Paljarvi T. The role of modifiable risk factors in incident cancer in transport, rescue, and security industries. Ann Epidemiol 2023:83:71-77.e1.
487 Gémes K, Taipale H, Björkenstam E, Rahman S, Gustafsson K, Tanskanen A, Ekselius L, Mittendorfer-Rutz E, Helgesson M. The role of sociodemographic and clinical factors in the initiation and discontinuation of attention deficit hyperactivity disorder medication among young adults in Sweden. Front Psychiatry 2023:14:1152286.
488 Stenius J. The Rorschach Ego Impairment Index (EII-2) as a predictor of psychotherapy outcome and alliance development. Doctoral dissertation. Jyväskylä: University of Jyväskylä, 2021. JYU Dissertations 378. 74 p.
489 Taipale H, Tanskanen A, Tiihonen J. Safety of Antipsychotic Polypharmacy Versus Monotherapy in a Nationwide Cohort of 61,889 Patients With Schizophrenia. Am J Psychiatry 2023:180(5):377-385.
490 Tolppanen A-M, Taipale H, Koponen M, Tanskanen A, Lavikainen P, Paananen J, Tiihonen J, Hartikainen S. Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease. Pharmacoepidemiol Drug Saf 2017:26(8):875-889.
491 Kuivalainen S, Vehviläinen-Julkunen K, Louheranta O, Putkonen A, Repo-Tiihonen E, Tiihonen J. Seasonal variation of hospital violence, seclusion and restraint in a forensic psychiatric hospital. Int J Law Psychiatry 2017:52:1-6.
492 Laukkanen E, Kuosmanen L, Selander T, Vehviläinen-Julkunen K. Seclusion, restraint, and involuntary medication in Finnish psychiatric care: a register study with root-level data. Nord J Psychiatry 2020:74(6):439-443.
493 Joensuu M. Serotonin transporter availability in major depression. Single photon emission tomography studies on drug-naïve depressed subjects: comparison with healthy subjects, effect of genotype, and follow-up during psychodynamic psychotherapy. Doctoral dissertation. Kuopio: University of Eastern Finland, 2019. Publications of the University of Eastern Finland. Dissertations in Health Sciences 513. 74 p.
494 Tiihonen J, Koskuvi M, Storvik M, Hyötyläinen I, Gao Y, Puttonen KA, Giniatullina R, Poguzhelskaya E, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Cheng L, Hill AF, Lähteenvuo M, et al. Sex-specific transcriptional and proteomic signatures in schizophrenia. Nat Commun 2019:10(1):3933.
495 Solmi M, Croatto G, Fabiano N, Wong S, Gupta A, Fornaro M, Schneider LK, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J, Cortese S, Dragioti E, Rietz E, Nielsen RE, Firth J, Fusar-Poli P, et al. Sex-stratified mortality estimates in people with schizophrenia: A systematic review and meta-analysis of cohort studies of 2,700,825 people with schizophrenia. Eur Neuropsychopharmacology 2025:91:56-66.
496 Cullen AE, Pettersson E, Lindsäter E, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Helgesson M. Sick leave patterns before and after commencement of psychological therapy among individuals with common mental disorders: a register-based, quasi-experimental study. BMC Psychiatry 2026:26(1):87.
497 Kirchner S, Gémes K, Josefsson P, Haro JM, Felez-Nobrega M, Taipale H, Sijbrandij M, Witteveen AB, Melchior M, Caggiu G, Conflitti C, Lora A, Compagnoni MM, Bergström J, Mittendorfer-Rutz E. Sickness absence due to common mental disorders and antidepressant prescription among health and social care workers during compared with before the COVID-19 pandemic: a nationwide register study of the Swedish population. J Occup Health 2026:68(1):uiaf067.
498 Tuppurainen H, Kivistö P, Repo-Tiihonen E, Tiihonen J. Skitsofrenian Käypä hoito -suosituksen toteutuminen Niuvanniemen sairaalassa. Suomen Lääkärilehti 2014:69(40):2549-2553.
499 Tiihonen J. Skitsofrenian lääkehoito. Duodecim 2019:135(20):2021-7.
500 Lieslehto J, Tiihonen J, Lähteenvuo M, Tanskanen A, Taipale H. Skitsofreniapotilaiden sitoutuminen psykoosilääkitykseen vaihtelee. Duodecim 2022:138(8):731.
501 Cederlöf E, Holm M, Kämpe A, Ahola-Olli A, Kantojärvi K, Lähteenvuo M, Ahti J, Hietala J, Häkkinen K, Isometsä E, Tuulio-Henriksson A, Kampman O, Lahdensuo K, Lönnqvist J, Tiihonen J, Turunen H, Wegelius A, Veijola J, Kieseppä T, et al. Sleep and schizophrenia polygenic scores in non-affective and affective psychotic disorders. Psychol Med 2025:55:e117.
502 Cederlöf E, Holm M, Lähteenvuo M, Haaki W, Hietala J, Häkkinen K, Isometsä E, Jukuri T, Kajanne R, Kampman O, Kieseppä T, Lahdensuo K, Lönnqvist J, Männynsalo T, Niemi-Pynttäri J, Suokas K, Suvisaari J, Tiihonen J, Turunen H, et al. Sleep in psychotic disorders: Results from nationwide SUPER Finland study. Schizophr Bull 2022:3(1):sgac011.
503 Elling DL, Thern E, Mangot-Sala L, Tiihonen J, Hammarberg A, Falkstedt D, Taipale H. Socio-economic differences in the effectiveness of pharmacotherapy use in alcohol use disorder: A cohort study of 148?626 individuals in Sweden. Addiction 2026:121(3):597-605.
504 Nestvold HH, Skurtveit SS, Hamina A, Hjellvik V, Odsbu I. Socioeconomic risk factors for long-term opioid use: A national registry-linkage study. Eur J Pain 2024:28(1):95-104.
505 Leppänen H, Kampman O, Autio R, Tanskanen A, Taipale H, Karolaakso T, Rissanen P, Näppilä T, Pirkola S. Socioeconomic status, antidepressant use, and return to work after disability due to common mental disorders. Eur Psychiatry 2025:68(1):e79.
506 Vu M, Kettunen R, Tolppanen A, Hartikainen S, Taipale H. Statin discontinuation in persons with and without Alzheimer's disease. Eur J Clin Pharmacol 2022:78(7):1145-1153.
507 Ojansuu I, Putkonen H, Lähteenvuo M, Tiihonen J. Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study. Front Psychiatry 2019:10:678.
508 Cederlöf E, Holm M, Ahti J, Lähteenvuo M, Hietala J, Häkkinen K, Isometsä E, Kampman O, Lahdensuo K, Lönnqvist J, Suvisaari J, Tiihonen J, Wegelius A, Veijola J, Palotie A, Kieseppä T, Niemelä S, Paunio T. Substance use and sleep problems in patients with psychotic disorders. Schizophr Bull Open 2023:4(1):sgac073.
509 Ahti J, Haaki W, Kieseppä T, Suvisaari J, Niemelä S, Suokas K, Torniainen-Holm M, Wegelius A, Kampman O, Lähteenvuo M, Paunio T, Tiihonen J, Hietala J, Isometsä ET. Suicidal acts and thoughts among persons with psychotic disorders in the Finnish SUPER study. Eur Psychiatry 2025:68(1):e99.
510 Mittendorfer-Rutz E, Bergström J, Josefsson P, Taipale H, Sijbrandij M, Witteveen A, Monzio Compagnoni M, Lora A, Felez-Nobrega M, Haro J, et al. Suicidal behavior in patients with severe mental disorders prior to and during the COVID-19 pandemic. Psychol Med 2024:54(16):4759-4767.
511 Antolín-Concha D, Lähteenvuo M, Vattulainen P, Tanskanen A, Taipale H, Vieta E, Tiihonen J. Suicide mortality and use of psychotropic drugs in patients hospitalized due to bipolar disorder: A Finnish nationwide cohort study. J Affect Disord 2020:277:885-892.
512 Helgesson M, Kjeldgård L, Björkenstam E, Rahman S, Gustafsson K, Taipale H, Tanskanen A, Ekselius L, Mittendorfer-Rutz E. Sustainable labour market participation among working young adults with diagnosed attention deficit/hyperactivity disorder (ADHD). SSM Popul Health 2023:23:101444.
513 Sivak L, Ojansuu I, Tiihonen J, Lähteenvuo M, Forsman J. Sweden vs. Finland - forensic psychiatric care and subsequent recidivism in violent crime. Nord J Psychiatry 2025:79(4):314-320.
514 Lampela P, Tanskanen A, Lähteenvuo M, Tiihonen J, Taipale H. Switches and early discontinuations of antidepressant medication in young adults with depression. J Affect Disord 2021:295:1474-1481.
515 Johanson M, Vaurio O, Tiihonen J, Lähteenvuo M. A Systematic Literature Review of Neuroimaging of Psychopathic Traits. Front Psychiatry 2020:10:1027.
516 Räsänen J, Ojansuu I, Tiihonen J, Lieslehto J, Lähteenvuo M. Systematic review of stranger homicides by psychotic individuals. Schizophr Bull 2026:52(2):sbaf246.
517 Tolppanen A-M, Tiihonen M, Taipale H, Koponen M, Tanskanen A, Lavikainen P, Tiihonen J, Hartikainen S. Systemic Estrogen Use and Discontinuation After Alzheimer's Disease Diagnosis in Finland 2005-2012: A Nationwide Exposure-Matched Cohort Study. Drugs Aging 2018:35(11):985-992.
518 Tolmunen T, Suonmaa E, Ruusunen A, Voutilainen S, Lehto S. Tehoavatko omega-3-rasvahapot nuorten mielenterveys- ja oppimishäiriöihin? Suomen Lääkärilehti 2015:70(41):2695-2701.
519 Lieslehto J, Sanmark E, Tiihonen J, Seppänen A. Tekoäly psykiatrin työkaluna: haasteet, mahdollisuudet ja tulevaisuuden suuntaviivat. Suomen Lääkärilehti 2025:80(2):115-118.
520 Askola R, Nikkonen M, Putkonen H, Kylmä J, Louheranta O. The Therapeutic Approach to a Patient's Criminal Offense in a Forensic Mental Health Nurse-Patient Relationship-The Nurses' Perspectives. Perspect Psychiatr Care 2017:53(3):164-174.
521 Kautzky A, Gémes K, Ármannsdóttir B, Amin R, Akhtar A, Lieslehto J, Tanskanen A, Taipale H, Mittendorfer-Rutz E. Three years of medication-use sequences in incident bipolar disorder in Sweden reveal divergent patterns in native-born and immigrant populations. Transl Psychiatry 2026:16(1):38.
522 Verdoux H, Bittner RA, Hasan A, Qubad M, Wagner E, Lepetit A, Arrojo-Romero M, Bachmann C, Beex-Oosterhuis M, Bogers J, Celofiga A, Cohen D, de Berardis D, de Hert M, de Las Cuevas C, Ebdrup BH, ..., Taipale H, Tiihonen J, Tuppurainen H, et al. The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force. Eur Psychiatry 2025:68(1):e17.
523 Lehtonen J, Tiihonen J, Joensuu MMO, Lehto SM, Ahola PO, Saarinen PI, Valkonen-Korhonen M, Tolmunen T, Kuikka JT. Toward molecular psychotherapy of depression? In: Levy RA, Ablon JS, Kächele H, eds. Psychodynamic Psychotherapy Research, p. 219-232. New York: Springer, 2012.
524 Wang M, Vaez M, Dorner TE, Tiihonen J, Voss M, Ivert T, Mittendorfer-Rutz E. Trajectories and characteristics of work disability before and after acute myocardial infarction. Heart 2018:104(4):340-348.
525 Rahman S, Filatova S, Chen L, Bjökenstam E, Taipale H, Mittendorfner-Rutz E. Trajectories of antidepressant use and characteristics associated with trajectory groups among young refugees and their Swedish-born peers with diagnosed common mental disordersfindings from the REMAIN study. Soc Psychiatry Psychiatr Epidemiol 2022:57(2):305-317.
526 Helgesson M, Rahman S, Björkenstam E, Gustafsson K, Amin R, Taipale H, Tanskanen A, Ekselius L, Mittendorfer-Rutz E. Trajectories of labour market marginalisation among young adults with newly diagnosed attention-deficit/hyperactivity disorder (ADHD). Epidemiol Psychiatr Sci 2021:30:e67.
527 Di Thiene D, Mittendorfer-Rutz E, Rahman S, Wang M, Alexanderson K, Tiihonen J, La Torre G, Helgesson M. Trajectories of sickness absence, disability pension and unemployment in young immigrants with common mental disorders. Eur J Public Health 2019:29(6):1055-1062.
528 Helgesson M, Pettersson E, Lindsäter E, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Cullen AE. Trajectories of work disability among individuals with anxiety-, mood/affective-, or stress-related disorders in a primary healthcare setting. BMC Psychiatry 2024:24(1):623.
529 Luykx JJ, Colgan M, Vieta E, Hamina A, Schulte PF, Correll CU, Mittendorfer-Rutz E, Siskind D, Lieslehto J, Tanskanen A, Tiihonen J, Taipale H. Transdiagnostic effectiveness and safety of clozapine in individuals with psychotic, affective, and personality disorders: nationwide and meta-analytic comparisons with other antipsychotics. Lancet Psychiatry 2025:12(12):921-931.
530 Kautzky A, Petterson E, Amin R, Akhtar A, Tanskanen A, Taipale H, et al. Treatment Patterns for Incident Bipolar Disorder Among Nonrefugee Immigrants, Refugees, Second-Generation Immigrants, and Host Population in Sweden. Bipolar Disord 2025:27(3):192-204.
531 Kurko T, Saastamoinen LK, Tuulio-Henriksson A, Taiminen T, Tiihonen J, Airaksinen M, Hietala J. Trends in the long-term use of benzodiazepine anxiolytics and hypnotics: A national register study for 2006 to 2014. Pharmacoepidemiol Drug Saf 2018:27(6):674-682.
532 Uosukainen H, Kauhanen J, Voutilainen S, Föhr J, Paasolainen M, Tiihonen J, Laitinen K, Onyeka IN, Bell JS. Twelve-year trend in treatment seeking for buprenorphine abuse in Finland. Drug Alcohol Depend 2013:127:207-214.
533 Poranen J, Koistinaho A, Tanskanen A, Tiihonen J, Taipale H, Lähteenvuo M. Twenty-year medication use trends in first-episode bipolar disorder. Acta Psychiatr Scand 2022:146(6):583-593.
534 Lampela P, Tolppanen AM, Tanskanen A, Tiihonen J, Lavikainen P, Hartikainen S, Taipale H. Use of antidementia drugs and risk of pneumonia in older persons with Alzheimer's disease. Ann Med 2017:49(3):230-239.
535 Puranen A, Koponen M, Tanskanen A, Tiihonen J, Taipale H. Use of antidepressants and mood stabilizers in persons with first-episode schizophrenia. Eur J Clin Pharmacol 2020:76(5):711-718.
536 Taipale H, Gomm W, Broich K, Maier W, Tolppanen A-M, Tanskanen A, Tiihonen J, Hartikainen S, Haenisch B. Use of Antiepileptic Drugs and Dementia Risk-an Analysis of Finnish Health Register and German Health Insurance Data. J Am Geriatr Soc 2018:66(6):1123-1129.
537 Hamina A, Paljärvi T, Tanskanen A, Lähteenvuo M, Tiihonen J, Taipale H. Use of antipsychotics and antidepressants in first-episode psychotic depression: A nationwide register-based study. Acta Psychiatr Scand 2023:148(5):416-425.
538 Lehti V, Salama E, Niemelä S, Tanskanen A, Gissler M, Suvisaari J, Taipale H. Use of benzodiazepine and related drugs in migrants and Finnish-born persons: a nationwide register-based study. Scand J Public Health 2023:51(8):1222-1230.
539 Taipale H, Koponen M, Tanskanen A, Lavikainen P, Tolppanen AM, Sund R, Tiihonen J, Hartikainen S. Use of benzodiazepines and related drugs is associated with a risk of stroke among persons with Alzheimer's disease. Int Clin Psychopharmacol 2017:32(3):135-141.
540 Asikainen J, Louheranta O, Vehviläinen-Julkunen K, Repo-Tiihonen E. Use of coercion prevention tools in Finnish psychiatric wards. Arch Psychiatr Nurs 2020:34(5):412-420.
541 Asikainen J, Vehviläinen-Julkunen K, Repo-Tiihonen E, Louheranta O. Use of debriefing following restrictive practices in forensic psychiatric care. J Forensic Pract 2023:25(1):46-56.
542 Tolppanen A-M, Taipale H, Koponen M, Lavikainen P, Tanskanen A, Tiihonen J, Hartikainen S. Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - the Medication use among persons with Alzheimer's disease (MEDALZ-2005) study. Clin Epidemiol 2013:5:277-285.
543 Tiihonen J. Use of lithium in patients with unipolar depression - Author's reply. Lancet Psychiatry 2017:4(9):663.
544 Tiihonen J. The use of long-acting injectables in early-phase schizophrenia. Lancet Psychiatry 2023:10(7):481-482.
545 Michel SF, Riaz M, Webster C, Hart SD, Levander S, Müller-Isberner R, Tiihonen J, Repo-Tiihonen E, Tuninger E, Hodgins S. Using the HCR-20 to predict aggressive behavior among men with schizophrenia living in the community: Accuracy of prediction, general and forensic settings, and dynamic risk factors. Int J Forensic Ment Health 2013:12(1):1-13.
546 Ahlgrén-Rimpiläinen A, Joelsson P, Kaarre H, Rautanen M, Niinistö K, Lindberg N, Tiihonen J. Vaarallisuuden arviointi - sattuman summaako. Edilex 2020:41:1-30.
547 Repo-Tiihonen E. Vaikeaa psykiatrista sairautta sairastavat ja oikeuspsykiatriset potilaat. Kirjassa: Keränen Tapani, Amos Pasternack, toim. Kliinisen tutkimuksen etiikka: opas tutkijoille ja eettisille toimikunnille, s. 70-73. Helsinki: Duodecim, 2015.
548 Solmi M, Thompson T, Estrade A, ..., Tiihonen J, et al. Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults. J Affect Disord 2023:326:249-261.
549 Lindeman S, Kolari T, Tiihonen J. Valproate and Neuroleptic Malignant Syndrome in an Elderly Patient With Schizoaffective Disorder. Prim Care Companion CNS Disord 2020:22(3):19/02542.
550 Asikainen J, Vehviläinen-Julkunen K, Repo-Tiihonen E, Louheranta O. Violence factors and debriefing in psychiatric inpatient care: A Review . J Psychosoc Nurs Ment Health Serv 2020:58(5):39-49.
551 Kuivalainen S, Vehviläinen-Julkunen K, Putkonen A, Louheranta O, Tiihonen J. Violent behaviour in a forensic psychiatric hospital in Finland: an analysis of violence incident reports. J Psychiatr Mental Health Nurs 2014:21(3):214-8.
552 Tiihonen J. Voisiko luonnon oma säilöntäaine mullistaa psykoosin hoidon? Pääkirjoitus. Duodecim 2013:129:2098-2099.
553 Kuosmanen A, Tiihonen J, Repo-Tiihonen E, Turunen H. Voluntary patient safety incidents reporting in forensic psychiatry-What do the reports tell us? J Psychiatr Mental Health Nurs 2022:29(1):36-47.
554 Rossi R, Pievani M, Järvenpää T, Testa C, Koskenvuo M, Räihä I, Kaprio J, Frisoni GB, Rinne JO, Laakso MP, Laakso MP. Voxel-based morphometry study on monozygotic twins discordant for Alzheimer's disease. Acta Neurol Scand 2016:133(6):427-33.
555 Tiihonen J. Vuoden 2022 Matti Äyräpään palkinnon saaja Jari Tiihonen; Lääkehoitojen vaikuttavuustutkimus vie kohti dataohjautuvaa terveydenhuoltoa. Duodecim 2022:138(23):2091-2092.
556 Lumén K, Louheranta O, Kuosmanen L. 'We Are the Cornerstone of This Hospital': First-Hand Accounts of Expert-By-Experience Practices in Forensic Psychiatry in Finland. Int J Ment Health Nurs 2025:34(3):e70079.
557 Lindner P, Budhiraja M, Westerman J, Savic I, Jokinen J, Tiihonen J, Hodgins S. White matter correlates of psychopathic traits in a female community sample. Soc Cogn Affect Neurosci 2017:12(9):1500-1510.
558 Sommer IE, Brand BA, Gangadin S, Tanskanen A, Tiihonen J, Taipale H. Women with Schizophrenia-Spectrum Disorders After Menopause: A Vulnerable Group for Relapse. Schizophr Bull 2023:49(1):136-143.
559 Vanhanen M, Hakola P, Ilonen T, Tiihonen J. Word list learning in patients with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy. Dement Geriatr Cogn Disord 2013:3:10-15.
560 Paakinaho A, Tiihonen M, Koskela H, Koponen M, Tiihonen J , Hartikainen S, Tolppainen A-M. ß2-Adrenoceptor Agonists in Asthma or Chronic Obstructive Pulmonary Disease and Risk of Parkinson's Disease: Nested Case-Control Study. Clin Epidemiol 2023:15:695-705.

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